O43399: Tumor protein D54
Protein names | - Tumor protein D54 - hD54 - Tumor protein D52-like 2 |
---|---|
Gene names | TPD52L2 |
Organism | Homo sapiens |
Protease Family | |
Protease ID | |
Chromosome location | |
UniProt ID | O43399 |
16
N-termini
2
C-termini
2
Cleavages
0
Substrates
Sequence
10 20 30 40 50 60
MDSAGQDINL NSPNKGLLSD SMTDVPVDTG VAARTPAVEG LTEAEEEELR AELTKVEEEI
70 80 90 100 110 120
VTLRQVLAAK ERHCGELKRR LGLSTLGELK QNLSRSWHDV QVSSAYVKTS EKLGEWNEKV
130 140 150 160 170 180
TQSDLYKKTQ ETLSQAGQKT SAALSTVGSA ISRKLGDMRN SATFKSFEDR VGTIKSKVVG
190 200
DRENGSDNLP SSAGSGDKPL SDPAPF
Isoforms
- Isoform 2 of Tumor protein D54 - Isoform 3 of Tumor protein D54 - Isoform 4 of Tumor protein D54 - Isoform 5 of Tumor protein D54 - Isoform 6 of Tumor protein D54 - Isoform 7 of Tumor protein D54Sequence View
10 20 30 40 50 60
MDSAGQDINL NSPNKGLLSD SMTDVPVDTG VAARTPAVEG LTEAEEEELR AELTKVEEEI
70 80 90 100 110 120
VTLRQVLAAK ERHCGELKRR LGLSTLGELK QNLSRSWHDV QVSSAYVKTS EKLGEWNEKV
130 140 150 160 170 180
TQSDLYKKTQ ETLSQAGQKT SAALSTVGSA ISRKLGDMRN SATFKSFEDR VGTIKSKVVG
190 200
DRENGSDNLP SSAGSGDKPL SDPAPF
10 20 30 40 50 60
MDSAGQDINL NSPNKGLLSD SMTDVPVDTG VAARTPAVEG LTEAEEEELR AELTKVEEEI
70 80 90 100 110 120
VTLRQVLAAK ERHCGELKRR LGLSTLGELK QNLSRSWHDV QVSSAYVKTS EKLGEWNEKV
130 140 150 160 170 180
TQSDLYKKTQ ETLSQAGQKT SAALSTVGSA ISRKLGDMRN SATFKSFEDR VGTIKSKVVG
190 200
DRENGSDNLP SSAGSGDKPL SDPAPF
10 20 30 40 50 60
MDSAGQDINL NSPNKGLLSD SMTDVPVDTG VAARTPAVEG LTEAEEEELR AELTKVEEEI
70 80 90 100 110 120
VTLRQVLAAK ERHCGELKRR LGLSTLGELK QNLSRSWHDV QVSSAYVKTS EKLGEWNEKV
130 140 150 160 170 180
TQSDLYKKTQ ETLSQAGQKT SAALSTVGSA ISRKLGDMRN SATFKSFEDR VGTIKSKVVG
190 200
DRENGSDNLP SSAGSGDKPL SDPAPF
10 20 30 40 50 60
MDSAGQDINL NSPNKGLLSD SMTDVPVDTG VAARTPAVEG LTEAEEEELR AELTKVEEEI
70 80 90 100 110 120
VTLRQVLAAK ERHCGELKRR LGLSTLGELK QNLSRSWHDV QVSSAYVKTS EKLGEWNEKV
130 140 150 160 170 180
TQSDLYKKTQ ETLSQAGQKT SAALSTVGSA ISRKLGDMRN SATFKSFEDR VGTIKSKVVG
190 200
DRENGSDNLP SSAGSGDKPL SDPAPF
10 20 30 40 50 60
MDSAGQDINL NSPNKGLLSD SMTDVPVDTG VAARTPAVEG LTEAEEEELR AELTKVEEEI
70 80 90 100 110 120
VTLRQVLAAK ERHCGELKRR LGLSTLGELK QNLSRSWHDV QVSSAYVKTS EKLGEWNEKV
130 140 150 160 170 180
TQSDLYKKTQ ETLSQAGQKT SAALSTVGSA ISRKLGDMRN SATFKSFEDR VGTIKSKVVG
190 200
DRENGSDNLP SSAGSGDKPL SDPAPF
10 20 30 40 50 60
MDSAGQDINL NSPNKGLLSD SMTDVPVDTG VAARTPAVEG LTEAEEEELR AELTKVEEEI
70 80 90 100 110 120
VTLRQVLAAK ERHCGELKRR LGLSTLGELK QNLSRSWHDV QVSSAYVKTS EKLGEWNEKV
130 140 150 160 170 180
TQSDLYKKTQ ETLSQAGQKT SAALSTVGSA ISRKLGDMRN SATFKSFEDR VGTIKSKVVG
190 200
DRENGSDNLP SSAGSGDKPL SDPAPF
Protein Neighborhood
Domains & Features
16 N-termini - 2 C-termini - 2 Cleavages - 0 Substrates
N-termini
Name | Sequence | Position | Modification | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMID) |
---|---|---|---|---|---|---|---|---|---|
O43399-1-Acetylation | MDSAGQ... | 1 | acetylation- | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | ||
O43399-1-Acetylation | MDSAGQ... | 1 | acetylation- | COFRADIC | Gevaert K. | Van Damme P et al.: Complementary positional proteomics for screening substrates... | 20526345 | ||
O43399-1-Acetylation | MDSAGQ... | 1 | acetylation- | other | CNRS/ISV | Large_scale_NTA_Human | |||
O43399-1-Acetylation | MDSAGQ... | 1 | acetylation- | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt96280 | ||
O43399-1-Acetylation | MDSAGQ... | 1 | acetylation- | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt96281 | ||
O43399-1-Acetylation | MDSAGQ... | 1 | acetylation- | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt96282 | ||
O43399-1-Acetylation | MDSAGQ... | 1 | acetylation- | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt96283 | ||
O43399-1-Acetylation | MDSAGQ... | 1 | acetylation- | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt96284 | ||
O43399-1-unknown | MDSAGQ... | 1 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt92832 | |||
O43399-1-unknown | MDSAGQ... | 1 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt92833 | |||
O43399-1-unknown | MDSAGQ... | 1 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt92834 | |||
O43399-1-unknown | MDSAGQ... | 1 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt92835 | |||
O43399-1-unknown | MDSAGQ... | 1 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt92837 | |||
O43399-1-unknown | MDSAGQ... | 1 | COFRADIC | Gevaert K. | Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates... | 20526345 | |||
O43399-3- | SAGQDI... | 3 | Subtiligase Based Positive Selection | Wells | apoptotic_DB_Doxo | 23264352 | |||
O43399-3- | SAGQDI... | 3 | Subtiligase Based Positive Selection | Wells | apoptotic_Jurkat_staurotrail | 23264352 | |||
O43399-3- | SAGQDI... | 3 | Subtiligase Based Positive Selection | Wells | apoptotic_MM1s_bort | 23264352 | |||
O43399-3-unknown | SAGQDI... | 3 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt165939 | |||
O43399-3-unknown | SAGQDI... | 3 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt165940 | |||
O43399-3-unknown | SAGQDI... | 3 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt165941 | |||
O43399-3-unknown | SAGQDI... | 3 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt165942 | |||
O43399-3-unknown | SAGQDI... | 3 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt165943 | |||
O43399-21- | SMTDVP... | 21 | Subtiligase Based Positive Selection | Wells | apoptotic_Jurkat_staurotrail | 23264352 | |||
O43399-21- | SMTDVP... | 21 | Subtiligase Based Positive Selection | Wells | apoptotic_MM1s_bort | 23264352 | |||
O43399-21- | SMTDVP... | 21 | Subtiligase Based Positive Selection | Wells | apoptotic_MM1SDBJurkat_Mix | 23264352 | |||
O43399-21- | SMTDVP... | 21 | Subtiligase Based Positive Selection | Wells | apoptosis_U266_bortezomib_induced | 23264352 | |||
O43399-21-unknown | SMTDVP... | 21 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC10753 | |||
O43399-21-unknown | SMTDVP... | 21 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC1092 | |||
O43399-21-unknown | SMTDVP... | 21 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt136892 | |||
O43399-21-unknown | SMTDVP... | 21 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt136893 | |||
O43399-21-unknown | SMTDVP... | 21 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt136894 | |||
O43399-21-unknown | SMTDVP... | 21 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt136895 | |||
O43399-21-unknown | SMTDVP... | 21 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt136896 | |||
O43399-27-unknown | VDTGVA... | 27 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt165872 | |||
O43399-27-unknown | VDTGVA... | 27 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt165873 | |||
O43399-27-unknown | VDTGVA... | 27 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt165874 | |||
O43399-27-unknown | VDTGVA... | 27 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt165875 | |||
O43399-27-unknown | VDTGVA... | 27 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt165876 | |||
O43399-27- | VDTGVA... | 27 | Subtiligase Based Positive Selection | Wells | apoptotic_DB_Doxo | 23264352 | |||
O43399-27- | VDTGVA... | 27 | Subtiligase Based Positive Selection | Wells | apoptotic_RPMI_Dox | 23264352 | |||
O43399-81- | LGLSTL... | 81 | Subtiligase Based Positive Selection | Wells | DB_Untreated | 23264352 | |||
O43399-81- | LGLSTL... | 81 | Subtiligase Based Positive Selection | Wells | apoptotic_RPMI_Dox | 23264352 | |||
O43399-81-unknown | LGLSTL... | 81 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt164245 | |||
O43399-81-unknown | LGLSTL... | 81 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt164244 | |||
O43399-81-unknown | LGLSTL... | 81 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt164246 | |||
O43399-81-unknown | LGLSTL... | 81 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt164247 | |||
O43399-81-unknown | LGLSTL... | 81 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt164248 | |||
O43399-81-unknown | LGLSTL... | 81 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt164249 | |||
O43399-109- | TSEKLG... | 109 | Subtiligase Based Positive Selection | Wells | DB_Untreated | 23264352 | |||
O43399-109-unknown | TSEKLG... | 109 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt164234 | |||
O43399-109-unknown | TSEKLG... | 109 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt164235 | |||
O43399-128-unknown | KTQETL... | 128 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt164228 | |||
O43399-128-unknown | KTQETL... | 128 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt164230 | |||
O43399-128-unknown | KTQETL... | 128 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt164231 | |||
O43399-128-unknown | KTQETL... | 128 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt164232 | |||
O43399-128-unknown | KTQETL... | 128 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt164227 | |||
O43399-128-unknown | KTQETL... | 128 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt164229 | |||
O43399-128- | KTQETL... | 128 | Subtiligase Based Positive Selection | Wells | DB_Untreated | 23264352 | |||
O43399-160-unknown | NSATFK... | 160 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt164238 | |||
O43399-160-unknown | NSATFK... | 160 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt164242 | |||
O43399-160-unknown | NSATFK... | 160 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt164240 | |||
O43399-160-unknown | NSATFK... | 160 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt164241 | |||
O43399-160-unknown | NSATFK... | 160 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt164239 | |||
O43399-160-unknown | NSATFK... | 160 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt164237 | |||
O43399-160- | NSATFK... | 160 | Subtiligase Based Positive Selection | Wells | DB_Untreated | 23264352 |
C-termini
Name | Sequence | Position | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
---|---|---|---|---|---|---|---|---|
...GLLSDS | 20 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC10753 | |||
...GLLSDS | 20 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC1092 | |||
...DPAPF | 206 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
...DPAPF | 206 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt88454 | |||
...DPAPF | 206 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt88450 | |||
...DPAPF | 206 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt88452 | |||
...DPAPF | 206 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt88451 | |||
...DPAPF | 206 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt88453 | |||
...DPAPF | 206 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt88455 |
Cleavages
Protease | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
---|---|---|---|---|---|---|---|---|
GRAB_HUMAN | 20 | LSDS.|.SMTD | inferred from experiment | unknown | MEROPS | Gevaert K | Van Damme P et al.:Complementary positional proteo... (M14.017) | 20526345, |
CASP1_HUMAN | 20 | LSDS.|.SMTD | inferred from experiment | unknown | MEROPS | Wells JA | Agard NJ et al.:Inflammatory stimuli regulate c... (C14.001) | 20173201, |
Substrates
Substrate | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
---|