P98175: RNA-binding protein 10 {ECO:0000305}

General Information

Protein names	- RNA-binding protein 10 {ECO:0000305} - G patch domain-containing protein 9 - RNA-binding motif protein 10 - RNA-binding protein S1-1 {ECO:0000250\|UniProtKB:P70501} - S1-1
Gene names	RBM10
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	P98175

7 N-termini

3 C-termini

2 Cleavages

0 Substrates

Sequence

Isoforms

- Isoform 2 of RNA-binding protein 10 - Isoform 3 of RNA-binding protein 10 - Isoform 4 of RNA-binding protein 10 - Isoform 5 of RNA-binding protein 10

Sequence View

        10         20         30         40         50         60
MEYERRGGRG DRTGRYGATD RSQDDGGENR SRDHDYRDMD YRSYPREYGS QEGKHDYDDS
        70         80         90        100        110        120
SEEQSAEDSY EASPGSETQR RRRRRHRHSP TGPPGFPRDG DYRDQDYRTE QGEEEEEEED
       130        140        150        160        170        180
EEEEEKASNI VMLRMLPQAA TEDDIRGQLQ SHGVQAREVR LMRNKSSGQS RGFAFVEFSH
       190        200        210        220        230        240
LQDATRWMEA NQHSLNILGQ KVSMHYSDPK PKINEDWLCN KCGVQNFKRR EKCFKCGVPK
       250        260        270        280        290        300
SEAEQKLPLG TRLDQQTLPL GGRELSQGLL PLPQPYQAQG VLASQALSQG SEPSSENAND
       310        320        330        340        350        360
TIILRNLNPH STMDSILGAL APYAVLSSSN VRVIKDKQTQ LNRGFAFIQL STIVEAAQLL
       370        380        390        400        410        420
QILQALHPPL TIDGKTINVE FAKGSKRDMA SNEGSRISAA SVASTAIAAA QWAISQASQG
       430        440        450        460        470        480
GEGTWATSEE PPVDYSYYQQ DEGYGNSQGT ESSLYAHGYL KGTKGPGITG TKGDPTGAGP
       490        500        510        520        530        540
EASLEPGADS VSMQAFSRAQ PGAAPGIYQQ SAEASSSQGT AANSQSYTIM SPAVLKSELQ
       550        560        570        580        590        600
SPTHPSSALP PATSPTAQES YSQYPVPDVS TYQYDETSGY YYDPQTGLYY DPNSQYYYNA
       610        620        630        640        650        660
QSQQYLYWDG ERRTYVPALE QSADGHKETG APSKEGKEKK EKHKTKTAQQ IAKDMERWAR
       670        680        690        700        710        720
SLNKQKENFK NSFQPISSLR DDERRESATA DAGYAILEKK GALAERQHTS MDLPKLASDD
       730        740        750        760        770        780
RPSPPRGLVA AYSGESDSEE EQERGGPERE EKLTDWQKLA CLLCRRQFPS KEALIRHQQL
       790        800        810        820        830        840
SGLHKQNLEI HRRAHLSENE LEALEKNDME QMKYRDRAAE RREKYGIPEP PEPKRRKYGG
       850        860        870        880        890        900
ISTASVDFEQ PTRDGLGSDN IGSRMLQAMG WKEGSGLGRK KQGIVTPIEA QTRVRGSGLG
       910        920        930
ARGSSYGVTS TESYKETLHK TMVTRFNEAQ         10         20         30         40         50         60
MEYERRGGRG DRTGRYGATD RSQDDGGENR SRDHDYRDMD YRSYPREYGS QEGKHDYDDS
        70         80         90        100        110        120
SEEQSAEDSY EASPGSETQR RRRRRHRHSP TGPPGFPRDG DYRDQDYRTE QGEEEEEEED
       130        140        150        160        170        180
EEEEEKASNI VMLRMLPQAA TEDDIRGQLQ SHGVQAREVR LMRNKSSGQS RGFAFVEFSH
       190        200        210        220        230        240
LQDATRWMEA NQHSLNILGQ KVSMHYSDPK PKINEDWLCN KCGVQNFKRR EKCFKCGVPK
       250        260        270        280        290        300
SEAEQKLPLG TRLDQQTLPL GGRELSQGLL PLPQPYQAQG VLASQALSQG SEPSSENAND
       310        320        330        340        350        360
TIILRNLNPH STMDSILGAL APYAVLSSSN VRVIKDKQTQ LNRGFAFIQL STIVEAAQLL
       370        380        390        400        410        420
QILQALHPPL TIDGKTINVE FAKGSKRDMA SNEGSRISAA SVASTAIAAA QWAISQASQG
       430        440        450        460        470        480
GEGTWATSEE PPVDYSYYQQ DEGYGNSQGT ESSLYAHGYL KGTKGPGITG TKGDPTGAGP
       490        500        510        520        530        540
EASLEPGADS VSMQAFSRAQ PGAAPGIYQQ SAEASSSQGT AANSQSYTIM SPAVLKSELQ
       550        560        570        580        590        600
SPTHPSSALP PATSPTAQES YSQYPVPDVS TYQYDETSGY YYDPQTGLYY DPNSQYYYNA
       610        620        630        640        650        660
QSQQYLYWDG ERRTYVPALE QSADGHKETG APSKEGKEKK EKHKTKTAQQ IAKDMERWAR
       670        680        690        700        710        720
SLNKQKENFK NSFQPISSLR DDERRESATA DAGYAILEKK GALAERQHTS MDLPKLASDD
       730        740        750        760        770        780
RPSPPRGLVA AYSGESDSEE EQERGGPERE EKLTDWQKLA CLLCRRQFPS KEALIRHQQL
       790        800        810        820        830        840
SGLHKQNLEI HRRAHLSENE LEALEKNDME QMKYRDRAAE RREKYGIPEP PEPKRRKYGG
       850        860        870        880        890        900
ISTASVDFEQ PTRDGLGSDN IGSRMLQAMG WKEGSGLGRK KQGIVTPIEA QTRVRGSGLG
       910        920        930
ARGSSYGVTS TESYKETLHK TMVTRFNEAQ         10         20         30         40         50         60
MEYERRGGRG DRTGRYGATD RSQDDGGENR SRDHDYRDMD YRSYPREYGS QEGKHDYDDS
        70         80         90        100        110        120
SEEQSAEDSY EASPGSETQR RRRRRHRHSP TGPPGFPRDG DYRDQDYRTE QGEEEEEEED
       130        140        150        160        170        180
EEEEEKASNI VMLRMLPQAA TEDDIRGQLQ SHGVQAREVR LMRNKSSGQS RGFAFVEFSH
       190        200        210        220        230        240
LQDATRWMEA NQHSLNILGQ KVSMHYSDPK PKINEDWLCN KCGVQNFKRR EKCFKCGVPK
       250        260        270        280        290        300
SEAEQKLPLG TRLDQQTLPL GGRELSQGLL PLPQPYQAQG VLASQALSQG SEPSSENAND
       310        320        330        340        350        360
TIILRNLNPH STMDSILGAL APYAVLSSSN VRVIKDKQTQ LNRGFAFIQL STIVEAAQLL
       370        380        390        400        410        420
QILQALHPPL TIDGKTINVE FAKGSKRDMA SNEGSRISAA SVASTAIAAA QWAISQASQG
       430        440        450        460        470        480
GEGTWATSEE PPVDYSYYQQ DEGYGNSQGT ESSLYAHGYL KGTKGPGITG TKGDPTGAGP
       490        500        510        520        530        540
EASLEPGADS VSMQAFSRAQ PGAAPGIYQQ SAEASSSQGT AANSQSYTIM SPAVLKSELQ
       550        560        570        580        590        600
SPTHPSSALP PATSPTAQES YSQYPVPDVS TYQYDETSGY YYDPQTGLYY DPNSQYYYNA
       610        620        630        640        650        660
QSQQYLYWDG ERRTYVPALE QSADGHKETG APSKEGKEKK EKHKTKTAQQ IAKDMERWAR
       670        680        690        700        710        720
SLNKQKENFK NSFQPISSLR DDERRESATA DAGYAILEKK GALAERQHTS MDLPKLASDD
       730        740        750        760        770        780
RPSPPRGLVA AYSGESDSEE EQERGGPERE EKLTDWQKLA CLLCRRQFPS KEALIRHQQL
       790        800        810        820        830        840
SGLHKQNLEI HRRAHLSENE LEALEKNDME QMKYRDRAAE RREKYGIPEP PEPKRRKYGG
       850        860        870        880        890        900
ISTASVDFEQ PTRDGLGSDN IGSRMLQAMG WKEGSGLGRK KQGIVTPIEA QTRVRGSGLG
       910        920        930
ARGSSYGVTS TESYKETLHK TMVTRFNEAQ         10         20         30         40         50         60
MEYERRGGRG DRTGRYGATD RSQDDGGENR SRDHDYRDMD YRSYPREYGS QEGKHDYDDS
        70         80         90        100        110        120
SEEQSAEDSY EASPGSETQR RRRRRHRHSP TGPPGFPRDG DYRDQDYRTE QGEEEEEEED
       130        140        150        160        170        180
EEEEEKASNI VMLRMLPQAA TEDDIRGQLQ SHGVQAREVR LMRNKSSGQS RGFAFVEFSH
       190        200        210        220        230        240
LQDATRWMEA NQHSLNILGQ KVSMHYSDPK PKINEDWLCN KCGVQNFKRR EKCFKCGVPK
       250        260        270        280        290        300
SEAEQKLPLG TRLDQQTLPL GGRELSQGLL PLPQPYQAQG VLASQALSQG SEPSSENAND
       310        320        330        340        350        360
TIILRNLNPH STMDSILGAL APYAVLSSSN VRVIKDKQTQ LNRGFAFIQL STIVEAAQLL
       370        380        390        400        410        420
QILQALHPPL TIDGKTINVE FAKGSKRDMA SNEGSRISAA SVASTAIAAA QWAISQASQG
       430        440        450        460        470        480
GEGTWATSEE PPVDYSYYQQ DEGYGNSQGT ESSLYAHGYL KGTKGPGITG TKGDPTGAGP
       490        500        510        520        530        540
EASLEPGADS VSMQAFSRAQ PGAAPGIYQQ SAEASSSQGT AANSQSYTIM SPAVLKSELQ
       550        560        570        580        590        600
SPTHPSSALP PATSPTAQES YSQYPVPDVS TYQYDETSGY YYDPQTGLYY DPNSQYYYNA
       610        620        630        640        650        660
QSQQYLYWDG ERRTYVPALE QSADGHKETG APSKEGKEKK EKHKTKTAQQ IAKDMERWAR
       670        680        690        700        710        720
SLNKQKENFK NSFQPISSLR DDERRESATA DAGYAILEKK GALAERQHTS MDLPKLASDD
       730        740        750        760        770        780
RPSPPRGLVA AYSGESDSEE EQERGGPERE EKLTDWQKLA CLLCRRQFPS KEALIRHQQL
       790        800        810        820        830        840
SGLHKQNLEI HRRAHLSENE LEALEKNDME QMKYRDRAAE RREKYGIPEP PEPKRRKYGG
       850        860        870        880        890        900
ISTASVDFEQ PTRDGLGSDN IGSRMLQAMG WKEGSGLGRK KQGIVTPIEA QTRVRGSGLG
       910        920        930
ARGSSYGVTS TESYKETLHK TMVTRFNEAQ

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

7 N-termini - 3 C-termini - 2 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
P98175-1-unknown	MEYERR...	1	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P98175-1-unknown	MEYERR...	1	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt87080
P98175-1-unknown	MEYERR...	1	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt87081
P98175-1-unknown	MEYERR...	1	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt87082
P98175-135-unknown	MLPQAA...	135	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt167922
P98175-135-	MLPQAA...	135		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_bortezomib	23264352
P98175-135-	MLPQAA...	135		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
P98175-135-	MLPQAA...	135		Subtiligase Based Positive Selection		Wells	apoptotic_MM1SDBJurkat_Mix	23264352
P98175-135-	MLPQAA...	135		Subtiligase Based Positive Selection		Wells	apoptosis_U266_bortezomib_induced	23264352
P98175-277-unknown	QAQGVL...	277	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC11852
P98175-277-unknown	QAQGVL...	277	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt146565
P98175-277-unknown	QAQGVL...	277	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt146566
P98175-277-unknown	QAQGVL...	277	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt149265
P98175-729-unknown	VAAYSG...	729	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC14338
P98175-729-unknown	VAAYSG...	729	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt155321
P98175-729-unknown	VAAYSG...	729	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt155334
P98175-729-unknown	VAAYSG...	729	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt156117
P98175-840-unknown	GISTAS...	840	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt170941
P98175-840-unknown	GISTAS...	840	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt170942
P98175-840-unknown	GISTAS...	840	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt170943
P98175-840-	GISTAS...	840		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
P98175-840-	GISTAS...	840		Subtiligase Based Positive Selection		Wells	apoptosis_U266_bortezomib_induced	23264352

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...LPQPYQ	276	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC11852
...LPQPYQ	276	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt129871
...LPQPYQ	276	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt129872
...LPQPYQ	276	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt132651
...PPRGLV	728	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC14338
...PPRGLV	728	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt138754
...PPRGLV	728	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt138767
...PPRGLV	728	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt139580
...FNEAQ	930	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...FNEAQ	930	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt82700
...FNEAQ	930	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt82699
...FNEAQ	930	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt82698

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
GRAB_HUMAN	276	QPYQ.\|.QAQG	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:Analysis of protein processing ... (S01.010)	18836177,
GRAM_HUMAN	728	RGLV.\|.VAAY	inferred from experiment	unknown	MEROPS	Bovenschen N	de Poot SA et al.:Human and mouse granzyme M disp... (S01.139)	21564021,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)