Q9BZE4: Nucleolar GTP-binding protein 1

General Information

Protein names	- Nucleolar GTP-binding protein 1 - Chronic renal failure gene protein - GTP-binding protein NGB
Gene names	GTPBP4
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q9BZE4

6 N-termini

4 C-termini

2 Cleavages

0 Substrates

Sequence

Isoforms

- Isoform 2 of Nucleolar GTP-binding protein 1 - Isoform 3 of Nucleolar GTP-binding protein 1

Sequence View

        10         20         30         40         50         60
MAHYNFKKIT VVPSAKDFID LTLSKTQRKT PTVIHKHYQI HRIRHFYMRK VKFTQQNYHD
        70         80         90        100        110        120
RLSQILTDFP KLDDIHPFYA DLMNILYDKD HYKLALGQIN IAKNLVDNVA KDYVRLMKYG
       130        140        150        160        170        180
DSLYRCKQLK RAALGRMCTV IKRQKQSLEY LEQVRQHLSR LPTIDPNTRT LLLCGYPNVG
       190        200        210        220        230        240
KSSFINKVTR ADVDVQPYAF TTKSLFVGHM DYKYLRWQVV DTPGILDHPL EDRNTIEMQA
       250        260        270        280        290        300
ITALAHLRAA VLYVMDLSEQ CGHGLREQLE LFQNIRPLFI NKPLIVVANK CDVKRIAELS
       310        320        330        340        350        360
EDDQKIFTDL QSEGFPVIET STLTEEGVIK VKTEACDRLL AHRVETKMKG NKVNEVLNRL
       370        380        390        400        410        420
HLAIPTRRDD KERPPFIPEG VVARRKRMET EESRKKRERD LELEMGDDYI LDLQKYWDLM
       430        440        450        460        470        480
NLSEKHDKIP EIWEGHNIAD YIDPAIMKKL EELEKEEELR TAAGEYDSVS ESEDEEMLEI
       490        500        510        520        530        540
RQLAKQIREK KKLKILESKE KNTQGPRMPR TAKKVQRTVL EKEMRSLGVD MDDKDDAHYA
       550        560        570        580        590        600
VQARRSRSIT RKRKREDSAP PSSVARSGSC SRTPRDVSGL RDVKMVKKAK TMMKNAQKKM
       610        620        630
NRLGKKGEAD RHVFDMKPKH LLSGKRKAGK KDRR         10         20         30         40         50         60
MAHYNFKKIT VVPSAKDFID LTLSKTQRKT PTVIHKHYQI HRIRHFYMRK VKFTQQNYHD
        70         80         90        100        110        120
RLSQILTDFP KLDDIHPFYA DLMNILYDKD HYKLALGQIN IAKNLVDNVA KDYVRLMKYG
       130        140        150        160        170        180
DSLYRCKQLK RAALGRMCTV IKRQKQSLEY LEQVRQHLSR LPTIDPNTRT LLLCGYPNVG
       190        200        210        220        230        240
KSSFINKVTR ADVDVQPYAF TTKSLFVGHM DYKYLRWQVV DTPGILDHPL EDRNTIEMQA
       250        260        270        280        290        300
ITALAHLRAA VLYVMDLSEQ CGHGLREQLE LFQNIRPLFI NKPLIVVANK CDVKRIAELS
       310        320        330        340        350        360
EDDQKIFTDL QSEGFPVIET STLTEEGVIK VKTEACDRLL AHRVETKMKG NKVNEVLNRL
       370        380        390        400        410        420
HLAIPTRRDD KERPPFIPEG VVARRKRMET EESRKKRERD LELEMGDDYI LDLQKYWDLM
       430        440        450        460        470        480
NLSEKHDKIP EIWEGHNIAD YIDPAIMKKL EELEKEEELR TAAGEYDSVS ESEDEEMLEI
       490        500        510        520        530        540
RQLAKQIREK KKLKILESKE KNTQGPRMPR TAKKVQRTVL EKEMRSLGVD MDDKDDAHYA
       550        560        570        580        590        600
VQARRSRSIT RKRKREDSAP PSSVARSGSC SRTPRDVSGL RDVKMVKKAK TMMKNAQKKM
       610        620        630
NRLGKKGEAD RHVFDMKPKH LLSGKRKAGK KDRR

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

6 N-termini - 4 C-termini - 2 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Evidence name
Q9BZE4-2-unknown	MAHYNF...	1		inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q9BZE4-2-Acetylation	AHYNFK...	2	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q9BZE4-48-unknown	MRKVKF...	48		inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000353168
Q9BZE4-48-unknown	MRKVKF...	48		inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000445473
Q9BZE4-117-unknown	MKYGDS...	117		inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000444277
Q9BZE4-528-unknown	GVDMDD...	528		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC14977
Q9BZE4-531-unknown	MDDKDD...	531		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC13265

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...SFINKV	187	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000353168
...EMRSLG	527	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC14977
...SLGVDM	530	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC13265
...KKDRR	634	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
GRAM_HUMAN	527	RSLG.\|.GVDM	inferred from experiment	unknown	MEROPS	Bovenschen N	de Poot SA et al.:Human and mouse granzyme M disp... (S01.139)	21564021,
GRAB_HUMAN	530	GVDM.\|.MDDK	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:Complementary positional proteo... (M14.017)	20526345,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)