P09543: 2',3'-cyclic-nucleotide 3'-phosphodiesterase

General Information

Protein names	- 2',3'-cyclic-nucleotide 3'-phosphodiesterase - CNP - CNPase - 3.1.4.37
Gene names	CNP
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	P09543

3 N-termini

3 C-termini

1 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MNRGFSRKSH TFLPKIFFRK MSSSGAKDKP ELQFPFLQDE DTVATLLECK TLFILRGLPG
        70         80         90        100        110        120
SGKSTLARVI VDKYRDGTKM VSADAYKITP GARGAFSEEY KRLDEDLAAY CRRRDIRILV
       130        140        150        160        170        180
LDDTNHERER LEQLFEMADQ YQYQVVLVEP KTAWRLDCAQ LKEKNQWQLS ADDLKKLKPG
       190        200        210        220        230        240
LEKDFLPLYF GWFLTKKSSE TLRKAGQVFL EELGNHKAFK KELRQFVPGD EPREKMDLVT
       250        260        270        280        290        300
YFGKRPPGVL HCTTKFCDYG KAPGAEEYAQ QDVLKKSYSK AFTLTISALF VTPKTTGARV
       310        320        330        340        350        360
ELSEQQLQLW PSDVDKLSPT DNLPRGSRAH ITLGCAADVE AVQTGLDLLE ILRQEKGGSR
       370        380        390        400        410        420
GEEVGELSRG KLYSLGNGRW MLTLAKNMEV RAIFTGYYGK GKPVPTQGSR KGGALQSCTI

I

Isoforms

- Isoform CNPI of 2',3'-cyclic-nucleotide 3'-phosphodiesterase

Sequence View

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Protein Neighborhood

Domains & Features

3 N-termini - 3 C-termini - 1 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
P09543-1-unknown	MNRGFS...	1	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
P09543-21-unknown	MSSSGA...	21	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt71101
P09543-21-unknown	MSSSGA...	21	inferred from electronic annotation	unknown	TISdb	inferred from TISdb
P09543-85-unknown	AYKITP...	85	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC11151
P09543-85-unknown	AYKITP...	85	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt140308

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...MVSADA	84	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC11151
...MVSADA	84	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt123430
...ALQSCT	418	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...ALQSCT	418	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt92709
...SCTII	421	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt66719

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
GRAB_HUMAN	84	SADA.\|.AYKI	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:Complementary positional proteo... (M14.017)	20526345,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)