Q9NXV6: CDKN2A-interacting protein

General Information

Protein names	- CDKN2A-interacting protein - Collaborator of ARF
Gene names	CDKN2AIP
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q9NXV6

8 N-termini

4 C-termini

3 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MAQEVSEYLS QNPRVAAWVE ALRCDGETDK HWRHRRDFLL RNAGDLAPAG GAASASTDEA
        70         80         90        100        110        120
ADAESGTRNR QLQQLISFSM AWANHVFLGC RYPQKVMDKI LSMAEGIKVT DAPTYTTRDE
       130        140        150        160        170        180
LVAKVKKRGI SSSNEGVEEP SKKRVIEGKN SSAVEQDHAK TSAKTERASA QQENSSTCIG
       190        200        210        220        230        240
SAIKSESGNS ARSSGISSQN SSTSDGDRSV SSQSSSSVSS QVTTAGSGKA SEAEAPDKHG
       250        260        270        280        290        300
SASFVSLLKS SVNSHMTQST DSRQQSGSPK KSALEGSSAS ASQSSSEIEV PLLGSSGSSE
       310        320        330        340        350        360
VELPLLSSKP SSETASSGLT SKTSSEASVS SSVAKNSSSS GTSLLTPKSS SSTNTSLLTS
       370        380        390        400        410        420
KSTSQVAASL LASKSSSQTS GSLVSKSTSL ASVSQLASKS SSQTSTSQLP SKSTSQSSES
       430        440        450        460        470        480
SVKFSCKLTN EDVKQKQPFF NRLYKTVAWK LVAVGGFSPN VNHGELLNAA IEALKATLDV
       490        500        510        520        530        540
FFVPLKELAD LPQNKSSQES IVCELRCKSV YLGTGCGKSK ENAKAVASRE ALKLFLKKKV
       550        560        570        580
VVKICKRKYR GSEIEDLVLL DEESRPVNLP PALKHPQELL

Isoforms

Sequence View

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Protein Neighborhood

Domains & Features

8 N-termini - 4 C-termini - 3 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q9NXV6-2-unknown	MAQEVS...	1		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q9NXV6-2-Acetylation	AQEVSE...	2	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q9NXV6-2-Acetylation	AQEVSE...	2	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345
Q9NXV6-2-Acetylation	AQEVSE...	2	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345
Q9NXV6-129-	GISSSN...	129			Subtiligase Based Positive Selection		Wells	Jurkat_untreated	23264352
Q9NXV6-158-unknown	HAKTSA...	158		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC13434
Q9NXV6-249-unknown	KSSVNS...	249		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC15066
Q9NXV6-308-unknown	SKPSSE...	308		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC6821
Q9NXV6-386-unknown	KSTSLA...	386			unknown			Mahrus S. et al.: nonapototic Jurkat cells, Global Sequencing of Proteolytic Cleavage...	18722006
Q9NXV6-387-	STSLAS...	387			Subtiligase Based Positive Selection		Wells	Jurkat_untreated	23264352

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...AVEQDH	157	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC13434
...FVSLLK	248	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC15066
...LPLLSS	307	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC6821
...PQELL	580	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
GRAB_HUMAN	157	EQDH.\|.HAKT	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:Complementary positional proteo... (M14.017)	20526345,
GRAM_HUMAN	248	SLLK.\|.KSSV	inferred from experiment	unknown	MEROPS	Bovenschen N	de Poot SA et al.:Human and mouse granzyme M disp... (S01.139)	21564021,
CATL1_HUMAN	307	LLSS.\|.SKPS	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)