TopFIND 4.0

O00154: Cytosolic acyl coenzyme A thioester hydrolase

General Information

Protein names
- Cytosolic acyl coenzyme A thioester hydrolase
- 3.1.2.2 {ECO:0000305|PubMed:10578051}
- Acyl-CoA thioesterase 7
- Brain acyl-CoA hydrolase
- BACH
- hBACH {ECO:0000303|PubMed:10578051}
- CTE-IIa
- CTE-II
- Long chain acyl-CoA thioester hydrolase
Gene names ACOT7
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID O00154

6

N-termini

3

C-termini

2

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MKLLARALRL CEFGRQASSR RLVAGQGCVG PRRGCCAPVQ VVGPRADLPP CGACITGRIM 
        70         80         90        100        110        120 
RPDDANVAGN VHGGTILKMI EEAGAIISTR HCNSQNGERC VAALARVERT DFLSPMCIGE 
       130        140        150        160        170        180 
VAHVSAEITY TSKHSVEVQV NVMSENILTG AKKLTNKATL WYVPLSLKNV DKVLEVPPVV 
       190        200        210        220        230        240 
YSRQEQEEEG RKRYEAQKLE RMETKWRNGD IVQPVLNPEP NTVSYSQSSL IHLVGPSDCT 
       250        260        270        280        290        300 
LHGFVHGGVT MKLMDEVAGI VAARHCKTNI VTASVDAINF HDKIRKGCVI TISGRMTFTS 
       310        320        330        340        350        360 
NKSMEIEVLV DADPVVDSSQ KRYRAASAFF TYVSLSQEGR SLPVPQLVPE TEDEKKRFEE 
       370        380    
GKGRYLQMKA KRQGHAEPQP 

Isoforms

- Isoform 2 of Cytosolic acyl coenzyme A thioester hydrolase - Isoform 3 of Cytosolic acyl coenzyme A thioester hydrolase - Isoform 4 of Cytosolic acyl coenzyme A thioester hydrolase - Isoform 5 of Cytosolic acyl coenzyme A thioester hydrolase - Isoform 6 of Cytosolic acyl coenzyme A thioester hydrolase - Isoform 7 of Cytosolic acyl coenzyme A thioester hydrolase

Sequence View

        10         20         30         40         50         60 
MKLLARALRL CEFGRQASSR RLVAGQGCVG PRRGCCAPVQ VVGPRADLPP CGACITGRIM 
        70         80         90        100        110        120 
RPDDANVAGN VHGGTILKMI EEAGAIISTR HCNSQNGERC VAALARVERT DFLSPMCIGE 
       130        140        150        160        170        180 
VAHVSAEITY TSKHSVEVQV NVMSENILTG AKKLTNKATL WYVPLSLKNV DKVLEVPPVV 
       190        200        210        220        230        240 
YSRQEQEEEG RKRYEAQKLE RMETKWRNGD IVQPVLNPEP NTVSYSQSSL IHLVGPSDCT 
       250        260        270        280        290        300 
LHGFVHGGVT MKLMDEVAGI VAARHCKTNI VTASVDAINF HDKIRKGCVI TISGRMTFTS 
       310        320        330        340        350        360 
NKSMEIEVLV DADPVVDSSQ KRYRAASAFF TYVSLSQEGR SLPVPQLVPE TEDEKKRFEE 
       370        380    
GKGRYLQMKA KRQGHAEPQP          10         20         30         40         50         60 
MKLLARALRL CEFGRQASSR RLVAGQGCVG PRRGCCAPVQ VVGPRADLPP CGACITGRIM 
        70         80         90        100        110        120 
RPDDANVAGN VHGGTILKMI EEAGAIISTR HCNSQNGERC VAALARVERT DFLSPMCIGE 
       130        140        150        160        170        180 
VAHVSAEITY TSKHSVEVQV NVMSENILTG AKKLTNKATL WYVPLSLKNV DKVLEVPPVV 
       190        200        210        220        230        240 
YSRQEQEEEG RKRYEAQKLE RMETKWRNGD IVQPVLNPEP NTVSYSQSSL IHLVGPSDCT 
       250        260        270        280        290        300 
LHGFVHGGVT MKLMDEVAGI VAARHCKTNI VTASVDAINF HDKIRKGCVI TISGRMTFTS 
       310        320        330        340        350        360 
NKSMEIEVLV DADPVVDSSQ KRYRAASAFF TYVSLSQEGR SLPVPQLVPE TEDEKKRFEE 
       370        380    
GKGRYLQMKA KRQGHAEPQP          10         20         30         40         50         60 
MKLLARALRL CEFGRQASSR RLVAGQGCVG PRRGCCAPVQ VVGPRADLPP CGACITGRIM 
        70         80         90        100        110        120 
RPDDANVAGN VHGGTILKMI EEAGAIISTR HCNSQNGERC VAALARVERT DFLSPMCIGE 
       130        140        150        160        170        180 
VAHVSAEITY TSKHSVEVQV NVMSENILTG AKKLTNKATL WYVPLSLKNV DKVLEVPPVV 
       190        200        210        220        230        240 
YSRQEQEEEG RKRYEAQKLE RMETKWRNGD IVQPVLNPEP NTVSYSQSSL IHLVGPSDCT 
       250        260        270        280        290        300 
LHGFVHGGVT MKLMDEVAGI VAARHCKTNI VTASVDAINF HDKIRKGCVI TISGRMTFTS 
       310        320        330        340        350        360 
NKSMEIEVLV DADPVVDSSQ KRYRAASAFF TYVSLSQEGR SLPVPQLVPE TEDEKKRFEE 
       370        380    
GKGRYLQMKA KRQGHAEPQP          10         20         30         40         50         60 
MKLLARALRL CEFGRQASSR RLVAGQGCVG PRRGCCAPVQ VVGPRADLPP CGACITGRIM 
        70         80         90        100        110        120 
RPDDANVAGN VHGGTILKMI EEAGAIISTR HCNSQNGERC VAALARVERT DFLSPMCIGE 
       130        140        150        160        170        180 
VAHVSAEITY TSKHSVEVQV NVMSENILTG AKKLTNKATL WYVPLSLKNV DKVLEVPPVV 
       190        200        210        220        230        240 
YSRQEQEEEG RKRYEAQKLE RMETKWRNGD IVQPVLNPEP NTVSYSQSSL IHLVGPSDCT 
       250        260        270        280        290        300 
LHGFVHGGVT MKLMDEVAGI VAARHCKTNI VTASVDAINF HDKIRKGCVI TISGRMTFTS 
       310        320        330        340        350        360 
NKSMEIEVLV DADPVVDSSQ KRYRAASAFF TYVSLSQEGR SLPVPQLVPE TEDEKKRFEE 
       370        380    
GKGRYLQMKA KRQGHAEPQP          10         20         30         40         50         60 
MKLLARALRL CEFGRQASSR RLVAGQGCVG PRRGCCAPVQ VVGPRADLPP CGACITGRIM 
        70         80         90        100        110        120 
RPDDANVAGN VHGGTILKMI EEAGAIISTR HCNSQNGERC VAALARVERT DFLSPMCIGE 
       130        140        150        160        170        180 
VAHVSAEITY TSKHSVEVQV NVMSENILTG AKKLTNKATL WYVPLSLKNV DKVLEVPPVV 
       190        200        210        220        230        240 
YSRQEQEEEG RKRYEAQKLE RMETKWRNGD IVQPVLNPEP NTVSYSQSSL IHLVGPSDCT 
       250        260        270        280        290        300 
LHGFVHGGVT MKLMDEVAGI VAARHCKTNI VTASVDAINF HDKIRKGCVI TISGRMTFTS 
       310        320        330        340        350        360 
NKSMEIEVLV DADPVVDSSQ KRYRAASAFF TYVSLSQEGR SLPVPQLVPE TEDEKKRFEE 
       370        380    
GKGRYLQMKA KRQGHAEPQP          10         20         30         40         50         60 
MKLLARALRL CEFGRQASSR RLVAGQGCVG PRRGCCAPVQ VVGPRADLPP CGACITGRIM 
        70         80         90        100        110        120 
RPDDANVAGN VHGGTILKMI EEAGAIISTR HCNSQNGERC VAALARVERT DFLSPMCIGE 
       130        140        150        160        170        180 
VAHVSAEITY TSKHSVEVQV NVMSENILTG AKKLTNKATL WYVPLSLKNV DKVLEVPPVV 
       190        200        210        220        230        240 
YSRQEQEEEG RKRYEAQKLE RMETKWRNGD IVQPVLNPEP NTVSYSQSSL IHLVGPSDCT 
       250        260        270        280        290        300 
LHGFVHGGVT MKLMDEVAGI VAARHCKTNI VTASVDAINF HDKIRKGCVI TISGRMTFTS 
       310        320        330        340        350        360 
NKSMEIEVLV DADPVVDSSQ KRYRAASAFF TYVSLSQEGR SLPVPQLVPE TEDEKKRFEE 
       370        380    
GKGRYLQMKA KRQGHAEPQP 



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Protein Neighborhood

Domains & Features

6 N-termini - 3 C-termini - 2 Cleavages - 0 Substrates

N-termini

C-termini

Cleavages

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)