Q8IX01: SURP and G-patch domain-containing protein 2

General Information

Protein names	- SURP and G-patch domain-containing protein 2 - Arginine/serine-rich-splicing factor 14 - Splicing factor, arginine/serine-rich 14
Gene names	SUGP2
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q8IX01

5 N-termini

4 C-termini

3 Cleavages

0 Substrates

Sequence

Isoforms

- Isoform 3 of SURP and G-patch domain-containing protein 2 - Isoform 4 of SURP and G-patch domain-containing protein 2

Sequence View

        10         20         30         40         50         60
MAARRITQET FDAVLQEKAK RYHMDASGEA VSETLQFKAQ DLLRAVPRSR AEMYDDVHSD
        70         80         90        100        110        120
GRYSLSGSVA HSRDAGREGL RSDVFPGPSF RSSNPSISDD SYFRKECGRD LEFSHSDSRD
       130        140        150        160        170        180
QVIGHRKLGH FRSQDWKFAL RGSWEQDFGH PVSQESSWSQ EYSFGPSAVL GDFGSSRLIE
       190        200        210        220        230        240
KECLEKESRD YDVDHPGEAD SVLRGGSQVQ ARGRALNIVD QEGSLLGKGE TQGLLTAKGG
       250        260        270        280        290        300
VGKLVTLRNV STKKIPTVNR ITPKTQGTNQ IQKNTPSPDV TLGTNPGTED IQFPIQKIPL
       310        320        330        340        350        360
GLDLKNLRLP RRKMSFDIID KSDVFSRFGI EIIKWAGFHT IKDDIKFSQL FQTLFELETE
       370        380        390        400        410        420
TCAKMLASFK CSLKPEHRDF CFFTIKFLKH SALKTPRVDN EFLNMLLDKG AVKTKNCFFE
       430        440        450        460        470        480
IIKPFDKYIM RLQDRLLKSV TPLLMACNAY ELSVKMKTLS NPLDLALALE TTNSLCRKSL
       490        500        510        520        530        540
ALLGQTFSLA SSFRQEKILE AVGLQDIAPS PAAFPNFEDS TLFGREYIDH LKAWLVSSGC
       550        560        570        580        590        600
PLQVKKAEPE PMREEEKMIP PTKPEIQAKA PSSLSDAVPQ RADHRVVGTI DQLVKRVIEG
       610        620        630        640        650        660
SLSPKERTLL KEDPAYWFLS DENSLEYKYY KLKLAEMQRM SENLRGADQK PTSADCAVRA
       670        680        690        700        710        720
MLYSRAVRNL KKKLLPWQRR GLLRAQGLRG WKARRATTGT QTLLSSGTRL KHHGRQAPGL
       730        740        750        760        770        780
SQAKPSLPDR NDAAKDCPPD PVGPSPQDPS LEASGPSPKP AGVDISEAPQ TSSPCPSADI
       790        800        810        820        830        840
DMKTMETAEK LARFVAQVGP EIEQFSIENS TDNPDLWFLH DQNSSAFKFY RKKVFELCPS
       850        860        870        880        890        900
ICFTSSPHNL HTGGGDTTGS QESPVDLMEG EAEFEDEPPP REAELESPEV MPEEEDEDDE
       910        920        930        940        950        960
DGGEEAPAPG GAGKSEGSTP ADGLPGEAAE DDLAGAPALS QASSGTCFPR KRISSKSLKV
       970        980        990       1000       1010       1020
GMIPAPKRVC LIQEPKVHEP VRIAYDRPRG RPMSKKKKPK DLDFAQQKLT DKNLGFQMLQ
      1030       1040       1050       1060       1070       1080
KMGWKEGHGL GSLGKGIREP VSVGTPSEGE GLGADGQEHK EDTFDVFRQR MMQMYRHKRA

NK         10         20         30         40         50         60
MAARRITQET FDAVLQEKAK RYHMDASGEA VSETLQFKAQ DLLRAVPRSR AEMYDDVHSD
        70         80         90        100        110        120
GRYSLSGSVA HSRDAGREGL RSDVFPGPSF RSSNPSISDD SYFRKECGRD LEFSHSDSRD
       130        140        150        160        170        180
QVIGHRKLGH FRSQDWKFAL RGSWEQDFGH PVSQESSWSQ EYSFGPSAVL GDFGSSRLIE
       190        200        210        220        230        240
KECLEKESRD YDVDHPGEAD SVLRGGSQVQ ARGRALNIVD QEGSLLGKGE TQGLLTAKGG
       250        260        270        280        290        300
VGKLVTLRNV STKKIPTVNR ITPKTQGTNQ IQKNTPSPDV TLGTNPGTED IQFPIQKIPL
       310        320        330        340        350        360
GLDLKNLRLP RRKMSFDIID KSDVFSRFGI EIIKWAGFHT IKDDIKFSQL FQTLFELETE
       370        380        390        400        410        420
TCAKMLASFK CSLKPEHRDF CFFTIKFLKH SALKTPRVDN EFLNMLLDKG AVKTKNCFFE
       430        440        450        460        470        480
IIKPFDKYIM RLQDRLLKSV TPLLMACNAY ELSVKMKTLS NPLDLALALE TTNSLCRKSL
       490        500        510        520        530        540
ALLGQTFSLA SSFRQEKILE AVGLQDIAPS PAAFPNFEDS TLFGREYIDH LKAWLVSSGC
       550        560        570        580        590        600
PLQVKKAEPE PMREEEKMIP PTKPEIQAKA PSSLSDAVPQ RADHRVVGTI DQLVKRVIEG
       610        620        630        640        650        660
SLSPKERTLL KEDPAYWFLS DENSLEYKYY KLKLAEMQRM SENLRGADQK PTSADCAVRA
       670        680        690        700        710        720
MLYSRAVRNL KKKLLPWQRR GLLRAQGLRG WKARRATTGT QTLLSSGTRL KHHGRQAPGL
       730        740        750        760        770        780
SQAKPSLPDR NDAAKDCPPD PVGPSPQDPS LEASGPSPKP AGVDISEAPQ TSSPCPSADI
       790        800        810        820        830        840
DMKTMETAEK LARFVAQVGP EIEQFSIENS TDNPDLWFLH DQNSSAFKFY RKKVFELCPS
       850        860        870        880        890        900
ICFTSSPHNL HTGGGDTTGS QESPVDLMEG EAEFEDEPPP REAELESPEV MPEEEDEDDE
       910        920        930        940        950        960
DGGEEAPAPG GAGKSEGSTP ADGLPGEAAE DDLAGAPALS QASSGTCFPR KRISSKSLKV
       970        980        990       1000       1010       1020
GMIPAPKRVC LIQEPKVHEP VRIAYDRPRG RPMSKKKKPK DLDFAQQKLT DKNLGFQMLQ
      1030       1040       1050       1060       1070       1080
KMGWKEGHGL GSLGKGIREP VSVGTPSEGE GLGADGQEHK EDTFDVFRQR MMQMYRHKRA

NK

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

5 N-termini - 4 C-termini - 3 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q8IX01-1-unknown	MAARRI...	1	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q8IX01-1-unknown	MAARRI...	1	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt91055
Q8IX01-1-unknown	MAARRI...	1	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt91056
Q8IX01-301-unknown	GLDLKN...	301	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC14721
Q8IX01-301-unknown	GLDLKN...	301	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt149891
Q8IX01-301-unknown	GLDLKN...	301	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt149892
Q8IX01-656-unknown	CAVRAM...	656	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC12814
Q8IX01-656-unknown	CAVRAM...	656	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt155386
Q8IX01-656-unknown	CAVRAM...	656	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt155387
Q8IX01-802-unknown	IEQFSI...	802	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC12817
Q8IX01-802-unknown	IEQFSI...	802	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt156487
Q8IX01-802-unknown	IEQFSI...	802	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt156488
Q8IX01-902-	GGEEAP...	902		Subtiligase Based Positive Selection		Wells	apoptotic_DB_Doxo	23264352

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...QKIPLG	300	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC14721
...QKIPLG	300	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt133283
...QKIPLG	300	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt133284
...PTSADC	655	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC12814
...PTSADC	655	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt138821
...PTSADC	655	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt138822
...QVGPEI	801	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC12817
...QVGPEI	801	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt139969
...QVGPEI	801	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt139970
...KRANK	1082	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...KRANK	1082	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt86674

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
GRAM_HUMAN	300	IPLG.\|.GLDL	inferred from experiment	unknown	MEROPS	Bovenschen N	de Poot SA et al.:Human and mouse granzyme M disp... (S01.139)	21564021,
GRAB_HUMAN	655	SADC.\|.CAVR	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:Complementary positional proteo... (M14.017)	20526345,
GRAB_HUMAN	801	GPEI.\|.IEQF	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:Analysis of protein processing ... (S01.010)	18836177,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)