Q96HR8: H/ACA ribonucleoprotein complex non-core subunit NAF1

General Information

Protein names	- H/ACA ribonucleoprotein complex non-core subunit NAF1 - hNAF1
Gene names	NAF1
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q96HR8

4 N-termini

3 C-termini

2 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MEVVEAAAAQ LETLKFNGTD FGVGEGPAAP SPGSAPVPGT QPPLQSFEGS PDAGQTVEVK
        70         80         90        100        110        120
PAGEQPLQPV LNAVAAGTPA PQPQPPAESP ACGDCVTSPG AAEPARAPDS LETSDSDSDS
       130        140        150        160        170        180
DSETDSDSSS SSSSSSSSSS SSSSSCISLP PVLSDGDDDL QIEKENKNFP LKTKDELLLN
       190        200        210        220        230        240
ELPSVEELTI ILPEDIELKP LGMVSSIIEQ LVIIESMTNL PPVNEETVIF KSDRQAAGKI
       250        260        270        280        290        300
FEIFGPVAHP FYVLRFNSSD HIESKGIKIK ETMYFAPSMK DFTQYIFTEK LKQDKGSDAS
       310        320        330        340        350        360
WKNDQEPPPE ALDFSDDEKE KEAKQRKKSQ IQGRKKLKSE FNEPGEDFTE VHQNWNAHSS
       370        380        390        400        410        420
ASEHAKGYRN REFTRGFSRA RYPRSCHGRP PPQHFYNSEH MVSQETSGFP SQRQNNPIMP
       430        440        450        460        470        480
QYPFPLPVFD MHNFPLRPPP PPPPPPVNMG WATPNMAAHP LLNLPYSLPP PPPPPPLPPP
       490
PSSGDSNSHF GPYY

Isoforms

- Isoform 2 of H/ACA ribonucleoprotein complex non-core subunit NAF1

Sequence View

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Protein Neighborhood

Domains & Features

4 N-termini - 3 C-termini - 2 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Evidence name
Q96HR8-1-unknown	MEVVEA...	1		inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt82206
Q96HR8-1-Acetylation	MEVVEA...	1	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q96HR8-1-Acetylation	MEVVEA...	1	acetylation-	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt105018
Q96HR8-313-unknown	DFSDDE...	313		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC14837
Q96HR8-313-unknown	DFSDDE...	313		inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt150198
Q96HR8-348-unknown	FTEVHQ...	348		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC13071

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...PPEALD	312	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC14837
...PPEALD	312	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt133592
...EPGEDF	347	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC13071
...FGPYY	494	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
GRAM_HUMAN	312	EALD.\|.DFSD	inferred from experiment	unknown	MEROPS	Bovenschen N	de Poot SA et al.:Human and mouse granzyme M disp... (S01.139)	21564021,
GRAB_HUMAN	347	GEDF.\|.FTEV	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:Analysis of protein processing ... (S01.010)	18836177,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)