Q9BWU0: Kanadaptin

General Information

Protein names	- Kanadaptin - Human lung cancer oncogene 3 protein - HLC-3 - Kidney anion exchanger adapter protein - Solute carrier family 4 anion exchanger member 1 adapter protein
Gene names	SLC4A1AP
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q9BWU0

8 N-termini

5 C-termini

4 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MLAPLRNAPG REGATSPSPP TDATGSLGEW DVDRNVKTEG WVSKERISKL HRLRMADILS
        70         80         90        100        110        120
QSETLASQDL SGDFKKPALP VSPAARSKAP ASSSSNPEEV QKEGPTALQD SNSGEPDIPP
       130        140        150        160        170        180
PQPDCGDFRS LQEEQSRPPT AVSSPGGPAR APPYQEPPWG GPATAPYSLE TLKGGTILGT
       190        200        210        220        230        240
RSLKGTSYCL FGRLSGCDVC LEHPSVSRYH AVLQHRASGP DGECDSNGPG FYLYDLGSTH
       250        260        270        280        290        300
GTFLNKTRIP PRTYCRVHVG HVVRFGGSTR LFILQGPEED REAESELTVT QLKELRKQQQ
       310        320        330        340        350        360
ILLEKKMLGE DSDEEEEMDT SERKINAGSQ DDEMGCTWGM GEDAVEDDAE ENPIVLEFQQ
       370        380        390        400        410        420
EREAFYIKDP KKALQGFFDR EGEELEYEFD EQGHSTWLCR VRLPVDDSTG KQLVAEAIHS
       430        440        450        460        470        480
GKKKEAMIQC SLEACRILDT LGLLRQEAVS RKRKAKNWED EDFYDSDDDT FLDRTGLIEK
       490        500        510        520        530        540
KRLNRMKKAG KIDEKPETFE SLVAKLNDAE RELSEISERL KASSQVLSES PSQDSLDAFM
       550        560        570        580        590        600
SEMKSGSTLD GVSRKKLHLR TFELRKEQQR LKGLIKIVKP AEIPELKKTE TQTTGAENKA
       610        620        630        640        650        660
KKLTLPLFGA MKGGSKFKLK TGTVGKLPPK RPELPPTLMR MKDEPEVEEE EEEEEEEEKE
       670        680        690        700        710        720
KEEHEKKKLE DGSLSRPQPE IEPEAAVQEM RPPTDLTHFK ETQTHENMSQ LSEEEQNKDY
       730        740        750        760        770        780
QDCSKTTSLC AGPSASKNEY EKSRGELKKK KTPGPGKLPP TLSSKYPEDD PDYCVWVPPE
       790
GQSGDGRTHL NDKYGY

Isoforms

Sequence View

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

8 N-termini - 5 C-termini - 4 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q9BWU0-1-unknown	MLAPLR...	1		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q9BWU0-56-acetylation	ADILSQ...	56	acetylation-		other		CNRS/ISV	Large_scale_NTA_Human
Q9BWU0-141-	AVSSPG...	141			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_bortezomib	23264352
Q9BWU0-141-	AVSSPG...	141			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
Q9BWU0-344-unknown	AVEDDA...	344		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC13242
Q9BWU0-349-unknown	AEENPI...	349		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC13243
Q9BWU0-535-unknown	SLDAFM...	535		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC13244
Q9BWU0-538-	AFMSEM...	538			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
Q9BWU0-538-unknown	AFMSEM...	538		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC2323

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...GMGEDA	343	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC13242
...AVEDDA	348	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC13243
...SPSQDS	534	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC13244
...QDSLDA	537	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC2323
...DKYGY	796	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
GRAB_HUMAN	343	GEDA.\|.AVED	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:Complementary positional proteo... (M14.017)	20526345,
GRAB_HUMAN	348	EDDA.\|.AEEN	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:Analysis of protein processing ... (S01.010)	18836177,
GRAB_HUMAN	534	SQDS.\|.SLDA	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:Complementary positional proteo... (M14.017)	20526345,
CASP3_HUMAN	537	SLDA.\|.AFMS	inferred from experiment	unknown	MEROPS		Merops CASP3_HUMAN -> NADAP_HUMAN @537

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)