Q9Y5X2: Sorting nexin-8

General Information

Protein names	- Sorting nexin-8
Gene names	SNX8
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q9Y5X2

3 N-termini

7 C-termini

1 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MTGRAMDPLP AAAVGAAAEA EADEEADPPA SDLPTPQAIE PQAIVQQVPA PSRMQMPQGN
        70         80         90        100        110        120
PLLLSHTLQE LLARDTVQVE LIPEKKGLFL KHVEYEVSSQ RFKSSVYRRY NDFVVFQEML
       130        140        150        160        170        180
LHKFPYRMVP ALPPKRMLGA DREFIEARRR ALKRFVNLVA RHPLFSEDVV LKLFLSFSGS
       190        200        210        220        230        240
DVQNKLKESA QCVGDEFLNC KLATRAKDFL PADIQAQFAI SRELIRNIYN SFHKLRDRAE
       250        260        270        280        290        300
RIASRAIDNA ADLLIFGKEL SAIGSDTTPL PSWAALNSST WGSLKQALKG LSVEFALLAD
       310        320        330        340        350        360
KAAQQGKQEE NDVVEKLNLF LDLLQSYKDL CERHEKGVLH KHQRALHKYS LMKRQMMSAT
       370        380        390        400        410        420
AQNREPESVE QLESRIVEQE NAIQTMELRN YFSLYCLHQE TQLIHVYLPL TSHILRAFVN
       430        440        450        460
SQIQGHKEMS KVWNDLRPKL SCLFAGPHST LTPPCSPPED GLCPH

Isoforms

Sequence View

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

3 N-termini - 7 C-termini - 1 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
Q9Y5X2-1-unknown	MTGRAM...	1	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q9Y5X2-43-unknown	AIVQQV...	43	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC13658
Q9Y5X2-54-unknown	MQMPQG...	54	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000406954
Q9Y5X2-54-unknown	MQMPQG...	54	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000406212
Q9Y5X2-54-unknown	MQMPQG...	54	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000403608
Q9Y5X2-54-unknown	MQMPQG...	54	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000399127

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...AIEPQA	42	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC13658
...KHVEYE	95	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000399127
...PKRMLG	138	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000403608
...FLPADI	213	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000406212
...IRNIYN	229	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000406954
...KLRDRA	238	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000392437
...GLCPH	465	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
GRAB_HUMAN	42	EPQA.\|.AIVQ	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:Analysis of protein processing ... (S01.010)	18836177,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)