Q03701: CCAAT/enhancer-binding protein zeta

General Information

Protein names	- CCAAT/enhancer-binding protein zeta - CCAAT-box-binding transcription factor - CBF - CCAAT-binding factor
Gene names	CEBPZ
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q03701

4 N-termini

4 C-termini

2 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MAAVKEPLEF HAKRPWRPEE AVEDPDEEDE DNTSEAENGF SLEEVLRLGG TKQDYLMLAT
        70         80         90        100        110        120
LDENEEVIDG GKKGAIDDLQ QGELEAFIQN LNLAKYTKAS LVEEDEPAEK ENSSKKEVKI
       130        140        150        160        170        180
PKINNKNTAE SQRTSVNKVK NKNRPEPHSD ENGSTTPKVK KDKQNIFEFF ERQTLLLRPG
       190        200        210        220        230        240
GKWYDLEYSN EYSLKPQPQD VVSKYKTLAQ KLYQHEINLF KSKTNSQKGA SSTWMKAIVS
       250        260        270        280        290        300
SGTLGDRMAA MILLIQDDAV HTLQFVETLV NLVKKKGSKQ QCLMALDTFK ELLITDLLPD
       310        320        330        340        350        360
NRKLRIFSQR PFDKLEQLSS GNKDSRDRRL ILWYFEHQLK HLVAEFVQVL ETLSHDTLVT
       370        380        390        400        410        420
TKTRALTVAH ELLCNKPEEE KALLVQVVNK LGDPQNRIAT KASHLLETLL CKHPNMKGVV
       430        440        450        460        470        480
SGEVERLLFR SNISSKAQYY AICFLNQMAL SHEESELANK LITVYFCFFR TCVKKKDVES
       490        500        510        520        530        540
KMLSALLTGV NRAYPYSQTG DDKVREQIDT LFKVLHIVNF NTSVQALMLL FQVMNSQQTI
       550        560        570        580        590        600
SDRYYTALYR KMLDPGLMTC SKQAMFLNLV YKSLKADIVL RRVKAFVKRL LQVTCQQMPP
       610        620        630        640        650        660
FICGALYLVS EILKAKPGLR SQLDDHPESD DEENFIDAND DEDMEKFTDA DKETEIVKKL
       670        680        690        700        710        720
ETEETVPETD VETKKPEVAS WVHFDNLKGG KQLNKYDPFS RNPLFCGAEN TSLWELKKLS
       730        740        750        760        770        780
VHFHPSVALF AKTILQGNYI QYSGDPLQDF TLMRFLDRFV YRNPKPHKGK ENTDSVVMQP
       790        800        810        820        830        840
KRKHFIKDIR HLPVNSKEFL AKEESQIPVD EVFFHRYYKK VAVKEKQKRD ADEESIEDVD
       850        860        870        880        890        900
DEEFEELIDT FEDDNCFSSG KDDMDFAGNV KKRTKGAKDN TLDEDSEGSD DELGNLDDDE
       910        920        930        940        950        960
VSLGSMDDEE FAEVDEDGGT FMDVLDDESE SVPELEVHSK VSTKKSKRKG TDDFDFAGSF
       970        980        990       1000       1010       1020
QGPRKKKRNL NDSSLFVSAE EFGHLLDENM GSKFDNIGMN AMANKDNASL KQLRWEAERD
      1030       1040       1050
DWLHNRDAKS IIKKKKHFKK KRIKTTQKTK KQRK

Isoforms

Sequence View

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

4 N-termini - 4 C-termini - 2 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q03701-1-unknown	MAAVKE...	1	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q03701-686-unknown	NLKGGK...	686	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC11895
Q03701-918-	GGTFMD...	918		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
Q03701-918-	GGTFMD...	918		Subtiligase Based Positive Selection		Wells	apoptotic_MM1SDBJurkat_Mix	23264352
Q03701-1035-unknown	KKHFKK...	1035	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC11896

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...EYSLKP	195	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000391881
...WVHFDN	685	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC11895
...SIIKKK	1034	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC11896
...KKQRK	1054	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
GRAB_HUMAN	685	HFDN.\|.NLKG	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:Complementary positional proteo... (M14.017)	20526345,
GRAB_HUMAN	1034	IKKK.\|.KKHF	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:Complementary positional proteo... (M14.017)	20526345,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)