TopFIND 4.0

P41250: Glycine--tRNA ligase

General Information

Protein names
- Glycine--tRNA ligase
- 6.1.1.14 {ECO:0000269|PubMed:17544401, ECO:0000269|PubMed:24898252, ECO:0000269|PubMed:28675565}
- Diadenosine tetraphosphate synthetase {ECO:0000305|PubMed:19710017}
- Ap4A synthetase {ECO:0000305|PubMed:19710017}
- 2.7.7.- {ECO:0000269|PubMed:19710017}
- Glycyl-tRNA synthetase {ECO:0000303|PubMed:19710017}
- GlyRS {ECO:0000303|PubMed:19710017}
Gene names GARS
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID P41250

10

N-termini

2

C-termini

1

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MPSPRPVLLR GARAALLLLL PPRLLARPSL LLRRSLSAAS CPPISLPAAA SRSSMDGAGA 
        70         80         90        100        110        120 
EEVLAPLRLA VRQQGDLVRK LKEDKAPQVD VDKAVAELKA RKRVLEAKEL ALQPKDDIVD 
       130        140        150        160        170        180 
RAKMEDTLKR RFFYDQAFAI YGGVSGLYDF GPVGCALKNN IIQTWRQHFI QEEQILEIDC 
       190        200        210        220        230        240 
TMLTPEPVLK TSGHVDKFAD FMVKDVKNGE CFRADHLLKA HLQKLMSDKK CSVEKKSEME 
       250        260        270        280        290        300 
SVLAQLDNYG QQELADLFVN YNVKSPITGN DLSPPVSFNL MFKTFIGPGG NMPGYLRPET 
       310        320        330        340        350        360 
AQGIFLNFKR LLEFNQGKLP FAAAQIGNSF RNEISPRSGL IRVREFTMAE IEHFVDPSEK 
       370        380        390        400        410        420 
DHPKFQNVAD LHLYLYSAKA QVSGQSARKM RLGDAVEQGV INNTVLGYFI GRIYLYLTKV 
       430        440        450        460        470        480 
GISPDKLRFR QHMENEMAHY ACDCWDAESK TSYGWIEIVG CADRSCYDLS CHARATKVPL 
       490        500        510        520        530        540 
VAEKPLKEPK TVNVVQFEPS KGAIGKAYKK DAKLVMEYLA ICDECYITEM EMLLNEKGEF 
       550        560        570        580        590        600 
TIETEGKTFQ LTKDMINVKR FQKTLYVEEV VPNVIEPSFG LGRIMYTVFE HTFHVREGDE 
       610        620        630        640        650        660 
QRTFFSFPAV VAPFKCSVLP LSQNQEFMPF VKELSEALTR HGVSHKVDDS SGSIGRRYAR 
       670        680        690        700        710        720 
TDEIGVAFGV TIDFDTVNKT PHTATLRDRD SMRQIRAEIS ELPSIVQDLA NGNITWADVE 
       730    
ARYPLFEGQE TGKKETIEE

Isoforms



Sequence View



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Protein Neighborhood

Domains & Features

10 N-termini - 2 C-termini - 1 Cleavages - 0 Substrates

N-termini

C-termini

Cleavages

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)