Q9Y508: E3 ubiquitin-protein ligase RNF114

General Information

Protein names	- E3 ubiquitin-protein ligase RNF114 - 2.3.2.27 - RING finger protein 114 - RING-type E3 ubiquitin transferase RNF114 {ECO:0000305} - Zinc finger protein 228 - Zinc finger protein 313
Gene names	RNF114
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q9Y508

4 N-termini

2 C-termini

1 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MAAQQRDCGG AAQLAGPAAE ADPLGRFTCP VCLEVYEKPV QVPCGHVFCS ACLQECLKPK
        70         80         90        100        110        120
KPVCGVCRSA LAPGVRAVEL ERQIESTETS CHGCRKNFFL SKIRSHVATC SKYQNYIMEG
       130        140        150        160        170        180
VKATIKDASL QPRNVPNRYT FPCPYCPEKN FDQEGLVEHC KLFHSTDTKS VVCPICASMP
       190        200        210        220
WGDPNYRSAN FREHIQRRHR FSYDTFVDYD VDEEDMMNQV LQRSIIDQ

Isoforms

- Isoform 2 of E3 ubiquitin-protein ligase RNF114

Sequence View

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Protein Neighborhood

Domains & Features

4 N-termini - 2 C-termini - 1 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q9Y508-1-unknown	MAAQQR...	1	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q9Y508-1-unknown	MAAQQR...	1	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt87885
Q9Y508-15-unknown	AGPAAE...	15	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt172790
Q9Y508-15-	AGPAAE...	15		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
Q9Y508-211-unknown	VDEEDM...	211	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC13645

C-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
	...FVDYDV	210	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC13645
	...SIIDQ	228	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
GRAB_HUMAN	210	DYDV.\|.VDEE	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:Complementary positional proteo... (M14.017)	20526345,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)