Q9NWT1: p21-activated protein kinase-interacting protein 1

General Information

Protein names	- p21-activated protein kinase-interacting protein 1 - PAK/PLC-interacting protein 1 - hPIP1 - PAK1-interacting protein 1 - WD repeat-containing protein 84
Gene names	PAK1IP1
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q9NWT1

3 N-termini

4 C-termini

2 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MELVAGCYEQ VLFGFAVHPE PEACGDHEQW TLVADFTHHA HTASLSAVAV NSRFVVTGSK
        70         80         90        100        110        120
DETIHIYDMK KKIEHGALVH HSGTITCLKF YGNRHLISGA EDGLICIWDA KKWECLKSIK
       130        140        150        160        170        180
AHKGQVTFLS IHPSGKLALS VGTDKTLRTW NLVEGRSAFI KNIKQNAHIV EWSPRGEQYV
       190        200        210        220        230        240
VIIQNKIDIY QLDTASISGT ITNEKRISSV KFLSESVLAV AGDEEVIRFF DCDSLVCLCE
       250        260        270        280        290        300
FKAHENRVKD MFSFEIPEHH VIVSASSDGF IKMWKLKQDK KVPPSLLCEI NTNARLTCLG
       310        320        330        340        350        360
VWLDKVADMK ESLPPAAEPS PVSKEQSKIG KKEPGDTVHK EEKRSKPNTK KRGLTGDSKK
       370        380        390
ATKESGLIST KKRKMVEMLE KKRKKKKIKT MQ

Isoforms

Sequence View

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Protein Neighborhood

Domains & Features

3 N-termini - 4 C-termini - 2 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
Q9NWT1-1-unknown	MELVAG...	1	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q9NWT1-355-unknown	TGDSKK...	355	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC15061
Q9NWT1-358-unknown	SKKATK...	358	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC13431

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
...KKRGLT	354	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC15061
...GLTGDS	357	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC13431
...IKTMQ	392		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345,
...IKTMQ	392		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345,
...IKTMQ	392	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
...IKTMQ	392		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345,
...IKTMQ	392		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345,

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
GRAM_HUMAN	354	RGLT.\|.TGDS	inferred from experiment	unknown	MEROPS	Bovenschen N	de Poot SA et al.:Human and mouse granzyme M disp... (S01.139)	21564021,
GRAB_HUMAN	357	TGDS.\|.SKKA	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:Complementary positional proteo... (M14.017)	20526345,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)