O60784: Target of Myb protein 1
Protein names | - Target of Myb protein 1 |
---|---|
Gene names | TOM1 |
Organism | Homo sapiens |
Protease Family | |
Protease ID | |
Chromosome location | |
UniProt ID | O60784 |
9
N-termini
3
C-termini
1
Cleavages
0
Substrates
Sequence
10 20 30 40 50 60
MDFLLGNPFS SPVGQRIEKA TDGSLQSEDW ALNMEICDII NETEEGPKDA LRAVKKRIVG
70 80 90 100 110 120
NKNFHEVMLA LTVLETCVKN CGHRFHVLVA SQDFVESVLV RTILPKNNPP TIVHDKVLNL
130 140 150 160 170 180
IQSWADAFRS SPDLTGVVTI YEDLRRKGLE FPMTDLDMLS PIHTPQRTVF NSETQSGQDS
190 200 210 220 230 240
VGTDSSQQED SGQHAAPLPA PPILSGDTPI APTPEQIGKL RSELEMVSGN VRVMSEMLTE
250 260 270 280 290 300
LVPTQAEPAD LELLQELNRT CRAMQQRVLE LIPQIANEQL TEELLIVNDN LNNVFLRHER
310 320 330 340 350 360
FERFRTGQTT KAPSEAEPAA DLIDMGPDPA ATGNLSSQLA GMNLGSSSVR AGLQSLEASG
370 380 390 400 410 420
RLEDEFDMFA LTRGSSLADQ RKEVKYEAPQ ATDGLAGALD ARQQSTGAIP VTQACLMEDI
430 440 450 460 470 480
EQWLSTDVGN DAEEPKGVTS EEFDKFLEER AKAADRLPNL SSPSAEGPPG PPSGPAPRKK
490
TQEKDDDMLF AL
Isoforms
- Isoform 2 of Target of Myb protein 1 - Isoform 3 of Target of Myb protein 1 - Isoform 4 of Target of Myb protein 1Sequence View
10 20 30 40 50 60
MDFLLGNPFS SPVGQRIEKA TDGSLQSEDW ALNMEICDII NETEEGPKDA LRAVKKRIVG
70 80 90 100 110 120
NKNFHEVMLA LTVLETCVKN CGHRFHVLVA SQDFVESVLV RTILPKNNPP TIVHDKVLNL
130 140 150 160 170 180
IQSWADAFRS SPDLTGVVTI YEDLRRKGLE FPMTDLDMLS PIHTPQRTVF NSETQSGQDS
190 200 210 220 230 240
VGTDSSQQED SGQHAAPLPA PPILSGDTPI APTPEQIGKL RSELEMVSGN VRVMSEMLTE
250 260 270 280 290 300
LVPTQAEPAD LELLQELNRT CRAMQQRVLE LIPQIANEQL TEELLIVNDN LNNVFLRHER
310 320 330 340 350 360
FERFRTGQTT KAPSEAEPAA DLIDMGPDPA ATGNLSSQLA GMNLGSSSVR AGLQSLEASG
370 380 390 400 410 420
RLEDEFDMFA LTRGSSLADQ RKEVKYEAPQ ATDGLAGALD ARQQSTGAIP VTQACLMEDI
430 440 450 460 470 480
EQWLSTDVGN DAEEPKGVTS EEFDKFLEER AKAADRLPNL SSPSAEGPPG PPSGPAPRKK
490
TQEKDDDMLF AL
10 20 30 40 50 60
MDFLLGNPFS SPVGQRIEKA TDGSLQSEDW ALNMEICDII NETEEGPKDA LRAVKKRIVG
70 80 90 100 110 120
NKNFHEVMLA LTVLETCVKN CGHRFHVLVA SQDFVESVLV RTILPKNNPP TIVHDKVLNL
130 140 150 160 170 180
IQSWADAFRS SPDLTGVVTI YEDLRRKGLE FPMTDLDMLS PIHTPQRTVF NSETQSGQDS
190 200 210 220 230 240
VGTDSSQQED SGQHAAPLPA PPILSGDTPI APTPEQIGKL RSELEMVSGN VRVMSEMLTE
250 260 270 280 290 300
LVPTQAEPAD LELLQELNRT CRAMQQRVLE LIPQIANEQL TEELLIVNDN LNNVFLRHER
310 320 330 340 350 360
FERFRTGQTT KAPSEAEPAA DLIDMGPDPA ATGNLSSQLA GMNLGSSSVR AGLQSLEASG
370 380 390 400 410 420
RLEDEFDMFA LTRGSSLADQ RKEVKYEAPQ ATDGLAGALD ARQQSTGAIP VTQACLMEDI
430 440 450 460 470 480
EQWLSTDVGN DAEEPKGVTS EEFDKFLEER AKAADRLPNL SSPSAEGPPG PPSGPAPRKK
490
TQEKDDDMLF AL
10 20 30 40 50 60
MDFLLGNPFS SPVGQRIEKA TDGSLQSEDW ALNMEICDII NETEEGPKDA LRAVKKRIVG
70 80 90 100 110 120
NKNFHEVMLA LTVLETCVKN CGHRFHVLVA SQDFVESVLV RTILPKNNPP TIVHDKVLNL
130 140 150 160 170 180
IQSWADAFRS SPDLTGVVTI YEDLRRKGLE FPMTDLDMLS PIHTPQRTVF NSETQSGQDS
190 200 210 220 230 240
VGTDSSQQED SGQHAAPLPA PPILSGDTPI APTPEQIGKL RSELEMVSGN VRVMSEMLTE
250 260 270 280 290 300
LVPTQAEPAD LELLQELNRT CRAMQQRVLE LIPQIANEQL TEELLIVNDN LNNVFLRHER
310 320 330 340 350 360
FERFRTGQTT KAPSEAEPAA DLIDMGPDPA ATGNLSSQLA GMNLGSSSVR AGLQSLEASG
370 380 390 400 410 420
RLEDEFDMFA LTRGSSLADQ RKEVKYEAPQ ATDGLAGALD ARQQSTGAIP VTQACLMEDI
430 440 450 460 470 480
EQWLSTDVGN DAEEPKGVTS EEFDKFLEER AKAADRLPNL SSPSAEGPPG PPSGPAPRKK
490
TQEKDDDMLF AL
Protein Neighborhood
Domains & Features
9 N-termini - 3 C-termini - 1 Cleavages - 0 Substrates
N-termini
Name | Sequence | Position | Modification | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMID) |
---|---|---|---|---|---|---|---|---|---|
O60784-1-unknown | MDFLLG... | 1 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt92744 | |||
O60784-1-unknown | MDFLLG... | 1 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt92745 | |||
O60784-1-Acetylation | MDFLLG... | 1 | acetylation- | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | ||
O60784-1-Acetylation | MDFLLG... | 1 | acetylation- | COFRADIC | Gevaert K. | Van Damme P et al.: Complementary positional proteomics for screening substrates... | 20526345 | ||
O60784-1-Acetylation | MDFLLG... | 1 | acetylation- | other | CNRS/ISV | Large_scale_NTA_Human | |||
O60784-1-Acetylation | MDFLLG... | 1 | acetylation- | COFRADIC | Gevaert K. | Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates... | 20526345 | ||
O60784-1-Acetylation | MDFLLG... | 1 | acetylation- | N-TAILS | Overall Laboratory | Lange_Huesgen_et_al-RBC | |||
O60784-1-Acetylation | MDFLLG... | 1 | acetylation- | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt107184 | ||
O60784-1-Acetylation | MDFLLG... | 1 | acetylation- | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt107185 | ||
O60784-34-unknown | MEICDI... | 34 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt92746 | |||
O60784-34-unknown | MEICDI... | 34 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt100116 | |||
O60784-34-unknown | MEICDI... | 34 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt100117 | |||
O60784-158- | MLSPIH... | 158 | Subtiligase Based Positive Selection | Wells | apoptotic_Jurkat_Etoposide | 23264352 | |||
O60784-158- | MLSPIH... | 158 | Subtiligase Based Positive Selection | Wells | apoptotic_Jurkat_staurotrail | 23264352 | |||
O60784-158- | MLSPIH... | 158 | Subtiligase Based Positive Selection | Wells | apoptotic_MM1s_bort | 23264352 | |||
O60784-158- | MLSPIH... | 158 | Subtiligase Based Positive Selection | Wells | apoptotic_MM1SDBJurkat_Mix | 23264352 | |||
O60784-158-unknown | MLSPIH... | 158 | unknown | Mahrus S. et al.: apototic Jurkat cells, Global Sequencing of Proteolytic Cleavage... | 18722006 | ||||
O60784-158-unknown | MLSPIH... | 158 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt162232 | |||
O60784-158-unknown | MLSPIH... | 158 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt162233 | |||
O60784-185- | SSQQED... | 185 | Subtiligase Based Positive Selection | Wells | apoptotic_MM1s_bort | 23264352 | |||
O60784-185-unknown | SSQQED... | 185 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC10864 | |||
O60784-185-unknown | SSQQED... | 185 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt144302 | |||
O60784-185-unknown | SSQQED... | 185 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt144819 | |||
O60784-185-unknown | SSQQED... | 185 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt146071 | |||
O60784-461- | SSPSAE... | 461 | Subtiligase Based Positive Selection | Wells | apoptotic_Jurkat_bortezomib | 23264352 | |||
O60784-461-unknown | SSPSAE... | 461 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt167756 | |||
O60784-461-unknown | SSPSAE... | 461 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt167755 | |||
O60784-461-unknown | SSPSAE... | 461 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt167757 |
C-termini
Name | Sequence | Position | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
---|---|---|---|---|---|---|---|---|
...SVGTDS | 184 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC10864 | |||
...SVGTDS | 184 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt128095 | |||
...SVGTDS | 184 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt129371 | |||
...MLFAL | 492 | COFRADIC | Gevaert K. | Van Damme P et al.: Complementary positional proteomics for screening substrates... | 20526345, | |||
...MLFAL | 492 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
...MLFAL | 492 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt88363 | |||
...MLFAL | 492 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt88364 | |||
...MLFAL | 492 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt88362 | |||
...MLFAL | 492 | COFRADIC | Gevaert K. | Van Damme P et al.: Complementary positional proteomics for screening substrates... | 20526345, |
Cleavages
Protease | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
---|---|---|---|---|---|---|---|---|
GRAB_HUMAN | 184 | GTDS.|.SSQQ | inferred from experiment | unknown | MEROPS | Gevaert K | Van Damme P et al.:Complementary positional proteo... (M14.017) | 20526345, |
Substrates
Substrate | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
---|