Q14692: Ribosome biogenesis protein BMS1 homolog

General Information

Protein names	- Ribosome biogenesis protein BMS1 homolog - Ribosome assembly protein BMS1 homolog
Gene names	BMS1
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q14692

6 N-termini

4 C-termini

2 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MEAKDQKKHR KKNSGPKAAK KKKRLLQDLQ LGDEEDARKR NPKAFAVQSA VRMARSFHRT
        70         80         90        100        110        120
QDLKTKKHHI PVVDRTPLEP PPIVVVVMGP PKVGKSTLIQ CLIRNFTRQK LTEIRGPVTI
       130        140        150        160        170        180
VSGKKRRLTI IECGCDINMM IDLAKVADLV LMLIDASFGF EMETFEFLNI CQVHGFPKIM
       190        200        210        220        230        240
GVLTHLDSFK HNKQLKKTKK RLKHRFWTEV YPGAKLFYLS GMVHGEYQNQ EIHNLGRFIT
       250        260        270        280        290        300
VMKFRPLTWQ TSHPYILADR MEDLTNPEDI RTNIKCDRKV SLYGYLRGAH LKNKSQIHMP
       310        320        330        340        350        360
GVGDFAVSDI SFLPDPCALP EQQKKRCLNE KEKLVYAPLS GVGGVLYDKD AVYVDLGGSH
       370        380        390        400        410        420
VFQDEVGPTH ELVQSLISTH STIDAKMASS RVTLFSDSKP LGSEDIDNQG LMMPKEEKQM
       430        440        450        460        470        480
DLNTGRMRRK AIFGDEDESG DSDDEEDDEM SEDDGLENGS SDEEAEEEEN AEMTDQYMAV
       490        500        510        520        530        540
KGIKRRKLEL EEDSEMDLPA FADSDDDLER SSAEEGEAEE ADESSEEEDC TAGEKGISGS
       550        560        570        580        590        600
KAAGEGSKAG LSPANCQSDR VNLEKSLLMK KAALPTFDSG HCTAEEVFAS EDESEESSSL
       610        620        630        640        650        660
SAEEEDSENE EAIRKKLSKP SQVSSGQKLG PQNFIDETSD IENLLKEEED YKEENNDSKE
       670        680        690        700        710        720
TSGALKWKED LSRKAAEAFL RQQQAAPNLR KLIYGTVTED NEEEDDDTLE ELGGLFRVNQ
       730        740        750        760        770        780
PDRECKHKAD SLDCSRFLVE APHDWDLEEV MNSIRDCFVT GKWEDDKDAA KVLAEDEELY
       790        800        810        820        830        840
GDFEDLETGD VHKGKSGPNT QNEDIEKEVK EEIDPDEEES AKKKHLDKKR KLKEMFDAEY
       850        860        870        880        890        900
DEGESTYFDD LKGEMQKQAQ LNRAEFEDQD DEARVQYEGF RPGMYVRIEI ENVPCEFVQN
       910        920        930        940        950        960
FDPHYPIILG GLGNSEGNVG YVQMRLKKHR WYKKILKSRD PIIFSVGWRR FQTIPLYYIE
       970        980        990       1000       1010       1020
DHNGRQRLLK YTPQHMHCGA AFWGPITPQG TGFLAIQSVS GIMPDFRIAA TGVVLDLDKS
      1030       1040       1050       1060       1070       1080
IKIVKKLKLT GFPYKIFKNT SFIKGMFNSA LEVAKFEGAV IRTVSGIRGQ IKKALRAPEG
      1090       1100       1110       1120       1130       1140
AFRASFEDKL LMSDIVFMRT WYPVSIPAFY NPVTSLLKPV GEKDTWSGMR TTGQLRLAHG
      1150       1160       1170       1180       1190       1200
VRLKANKDSL YKPILRQKKH FNSLHIPKAL QKALPFKNKP KTQAKAGKVP KDRRRPAVIR
      1210       1220       1230       1240       1250       1260
EPHERKILAL LDALSTVHSQ KMKKAKEQRH LHNKEHFRAK QKEEEEKLKR QKDLRKKLFR
      1270       1280
IQGQKERRNQ KSSLKGAEGQ LQ

Isoforms

Sequence View

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Evidence Names:

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Protein Neighborhood

Domains & Features

6 N-termini - 4 C-termini - 2 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q14692-1-unknown	MEAKDQ...	1	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q14692-412-unknown	MMPKEE...	412	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC14496
Q14692-476-unknown	QYMAVK...	476	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC12264
Q14692-500-	AFADSD...	500		Subtiligase Based Positive Selection		Wells	apoptotic_MM1s_bort	23264352
Q14692-769-	AAKVLA...	769		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
Q14692-769-	AAKVLA...	769		Subtiligase Based Positive Selection		Wells	apoptotic_MM1SDBJurkat_Mix	23264352
Q14692-772-	VLAEDE...	772		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
...DNQGLM	411	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC14496
...AEMTDQ	475	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC12264
...EGQLQ	1282	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
...EGQLQ	1282		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345,
...EGQLQ	1282		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345,
...EGQLQ	1282		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345,
...EGQLQ	1282		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345,

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
GRAM_HUMAN	411	QGLM.\|.MMPK	inferred from experiment	unknown	MEROPS	Bovenschen N	de Poot SA et al.:Human and mouse granzyme M disp... (S01.139)	21564021,
GRAB_HUMAN	475	MTDQ.\|.QYMA	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:Complementary positional proteo... (M14.017)	20526345,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)