O75821: Eukaryotic translation initiation factor 3 subunit G {ECO:0000255|HAMAP-Rule:MF_03006}

General Information

Protein names	- Eukaryotic translation initiation factor 3 subunit G {ECO:0000255\|HAMAP-Rule:MF_03006} - eIF3g {ECO:0000255\|HAMAP-Rule:MF_03006} - Eukaryotic translation initiation factor 3 RNA-binding subunit {ECO:0000255\|HAMAP-Rule:MF_03006} - eIF-3 RNA-binding subunit {ECO:0000255\|HAMAP-Rule:MF_03006} - Eukaryotic translation initiation factor 3 subunit 4 {ECO:0000255\|HAMAP-Rule:MF_03006} - eIF-3-delta {ECO:0000255\|HAMAP-Rule:MF_03006} - eIF3 p42 {ECO:0000255\|HAMAP-Rule:MF_03006} - eIF3 p44 {ECO:0000255\|HAMAP-Rule:MF_03006}
Gene names	EIF3G
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	O75821

5 N-termini

6 C-termini

2 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MPTGDFDSKP SWADQVEEEG EDDKCVTSEL LKGIPLATGD TSPEPELLPG APLPPPKEVI
        70         80         90        100        110        120
NGNIKTVTEY KIDEDGKKFK IVRTFRIETR KASKAVARRK NWKKFGNSEF DPPGPNVATT
       130        140        150        160        170        180
TVSDDVSMTF ITSKEDLNCQ EEEDPMNKLK GQKIVSCRIC KGDHWTTRCP YKDTLGPMQK
       190        200        210        220        230        240
ELAEQLGLST GEKEKLPGEL EPVQATQNKT GKYVPPSLRD GASRRGESMQ PNRRADDNAT
       250        260        270        280        290        300
IRVTNLSEDT RETDLQELFR PFGSISRIYL AKDKTTGQSK GFAFISFHRR EDAARAIAGV
       310        320
SGFGYDHLIL NVEWAKPSTN

Isoforms

Sequence View

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Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

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Protease Assignment Confidence:

Evidence Names:

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Protein Neighborhood

Domains & Features

5 N-termini - 6 C-termini - 2 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
O75821-2-unknown	PTGDFD...	2	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
O75821-33-	GIPLAT...	33		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_bortezomib	23264352
O75821-33-	GIPLAT...	33		Subtiligase Based Positive Selection		Wells	apoptotic_MM1s_bort	23264352
O75821-33-	GIPLAT...	33		Subtiligase Based Positive Selection		Wells	MM1SDBJurkat_Untreated	23264352
O75821-33-	GIPLAT...	33		Subtiligase Based Positive Selection		Wells	apoptotic_MM1SDBJurkat_Mix	23264352
O75821-33-	GIPLAT...	33		Subtiligase Based Positive Selection		Wells	apoptosis_U266_bortezomib_induced	23264352
O75821-151-unknown	GQKIVS...	151	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC5272
O75821-190-unknown	TGEKEK...	190	inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000467187
O75821-307-unknown	HLILNV...	307	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC10966

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...MNKLKG	150	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC5272
...QELFRP	260	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000465882
...LFRPFG	262	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000468159
...AARAIA	297	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000466860
...GFGYDH	306	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC10966
...KPSTN	320	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
CATL1_HUMAN	150	KLKG.\|.GQKI	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,
GRAB_HUMAN	306	GYDH.\|.HLIL	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:Complementary positional proteo... (M14.017)	20526345,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)