Q86XL3: Ankyrin repeat and LEM domain-containing protein 2

General Information

Protein names	- Ankyrin repeat and LEM domain-containing protein 2 - LEM domain-containing protein 4
Gene names	ANKLE2
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q86XL3

3 N-termini

2 C-termini

1 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MLWPRLAAAE WAALAWELLG ASVLLIAVRW LVRRLGPRPG GLGRSGTPVP PPSAAAAPAS
        70         80         90        100        110        120
GEMTMDALLA RLKLLNPDDL REEIVKAGLK CGPITSTTRF IFEKKLAQAL LEQGGRLSSF
       130        140        150        160        170        180
YHHEAGVTAL SQDPQRILKP AEGNPTDQAG FSEDRDFGYS VGLNPPEEEA VTSKTCSVPP
       190        200        210        220        230        240
SDTDTYRAGA TASKEPPLYY GVCPVYEDVP ARNERIYVYE NKKEALQAVK MIKGSRFKAF
       250        260        270        280        290        300
STREDAEKFA RGICDYFPSP SKTSLPLSPV KTAPLFSNDR LKDGLCLSES ETVNKERANS
       310        320        330        340        350        360
YKNPRTQDLT AKLRKAVEKG EEDTFSDLIW SNPRYLIGSG DNPTIVQEGC RYNVMHVAAK
       370        380        390        400        410        420
ENQASICQLT LDVLENPDFM RLMYPDDDEA MLQKRIRYVV DLYLNTPDKM GYDTPLHFAC
       430        440        450        460        470        480
KFGNADVVNV LSSHHLIVKN SRNKYDKTPE DVICERSKNK SVELKERIRE YLKGHYYVPL
       490        500        510        520        530        540
LRAEETSSPV IGELWSPDQT AEASHVSRYG GSPRDPVLTL RAFAGPLSPA KAEDFRKLWK
       550        560        570        580        590        600
TPPREKAGFL HHVKKSDPER GFERVGRELA HELGYPWVEY WEFLGCFVDL SSQEGLQRLE
       610        620        630        640        650        660
EYLTQQEIGK KAQQETGERE ASCRDKATTS GSNSISVRAF LDEDDMSLEE IKNRQNAARN
       670        680        690        700        710        720
NSPPTVGAFG HTRCSAFPLE QEADLIEAAE PGGPHSSRNG LCHPLNHSRT LAGKRPKAPR
       730        740        750        760        770        780
GEEAHLPPVS DLTVEFDKLN LQNIGRSVSK TPDESTKTKD QILTSRINAV ERDLLEPSPA
       790        800        810        820        830        840
DQLGNGHRRT ESEMSARIAK MSLSPSSPRH EDQLEVTREP ARRLFLFGEE PSKLDQDVLA
       850        860        870        880        890        900
ALECADVDPH QFPAVHRWKS AVLCYSPSDR QSWPSPAVKG RFKSQLPDLS GPHSYSPGRN
       910        920        930
SVAGSNPAKP GLGSPGRYSP VHGSQLRRMA RLAELAAL

Isoforms

- Isoform 2 of Ankyrin repeat and LEM domain-containing protein 2 - Isoform 3 of Ankyrin repeat and LEM domain-containing protein 2

Sequence View

        10         20         30         40         50         60
MLWPRLAAAE WAALAWELLG ASVLLIAVRW LVRRLGPRPG GLGRSGTPVP PPSAAAAPAS
        70         80         90        100        110        120
GEMTMDALLA RLKLLNPDDL REEIVKAGLK CGPITSTTRF IFEKKLAQAL LEQGGRLSSF
       130        140        150        160        170        180
YHHEAGVTAL SQDPQRILKP AEGNPTDQAG FSEDRDFGYS VGLNPPEEEA VTSKTCSVPP
       190        200        210        220        230        240
SDTDTYRAGA TASKEPPLYY GVCPVYEDVP ARNERIYVYE NKKEALQAVK MIKGSRFKAF
       250        260        270        280        290        300
STREDAEKFA RGICDYFPSP SKTSLPLSPV KTAPLFSNDR LKDGLCLSES ETVNKERANS
       310        320        330        340        350        360
YKNPRTQDLT AKLRKAVEKG EEDTFSDLIW SNPRYLIGSG DNPTIVQEGC RYNVMHVAAK
       370        380        390        400        410        420
ENQASICQLT LDVLENPDFM RLMYPDDDEA MLQKRIRYVV DLYLNTPDKM GYDTPLHFAC
       430        440        450        460        470        480
KFGNADVVNV LSSHHLIVKN SRNKYDKTPE DVICERSKNK SVELKERIRE YLKGHYYVPL
       490        500        510        520        530        540
LRAEETSSPV IGELWSPDQT AEASHVSRYG GSPRDPVLTL RAFAGPLSPA KAEDFRKLWK
       550        560        570        580        590        600
TPPREKAGFL HHVKKSDPER GFERVGRELA HELGYPWVEY WEFLGCFVDL SSQEGLQRLE
       610        620        630        640        650        660
EYLTQQEIGK KAQQETGERE ASCRDKATTS GSNSISVRAF LDEDDMSLEE IKNRQNAARN
       670        680        690        700        710        720
NSPPTVGAFG HTRCSAFPLE QEADLIEAAE PGGPHSSRNG LCHPLNHSRT LAGKRPKAPR
       730        740        750        760        770        780
GEEAHLPPVS DLTVEFDKLN LQNIGRSVSK TPDESTKTKD QILTSRINAV ERDLLEPSPA
       790        800        810        820        830        840
DQLGNGHRRT ESEMSARIAK MSLSPSSPRH EDQLEVTREP ARRLFLFGEE PSKLDQDVLA
       850        860        870        880        890        900
ALECADVDPH QFPAVHRWKS AVLCYSPSDR QSWPSPAVKG RFKSQLPDLS GPHSYSPGRN
       910        920        930
SVAGSNPAKP GLGSPGRYSP VHGSQLRRMA RLAELAAL         10         20         30         40         50         60
MLWPRLAAAE WAALAWELLG ASVLLIAVRW LVRRLGPRPG GLGRSGTPVP PPSAAAAPAS
        70         80         90        100        110        120
GEMTMDALLA RLKLLNPDDL REEIVKAGLK CGPITSTTRF IFEKKLAQAL LEQGGRLSSF
       130        140        150        160        170        180
YHHEAGVTAL SQDPQRILKP AEGNPTDQAG FSEDRDFGYS VGLNPPEEEA VTSKTCSVPP
       190        200        210        220        230        240
SDTDTYRAGA TASKEPPLYY GVCPVYEDVP ARNERIYVYE NKKEALQAVK MIKGSRFKAF
       250        260        270        280        290        300
STREDAEKFA RGICDYFPSP SKTSLPLSPV KTAPLFSNDR LKDGLCLSES ETVNKERANS
       310        320        330        340        350        360
YKNPRTQDLT AKLRKAVEKG EEDTFSDLIW SNPRYLIGSG DNPTIVQEGC RYNVMHVAAK
       370        380        390        400        410        420
ENQASICQLT LDVLENPDFM RLMYPDDDEA MLQKRIRYVV DLYLNTPDKM GYDTPLHFAC
       430        440        450        460        470        480
KFGNADVVNV LSSHHLIVKN SRNKYDKTPE DVICERSKNK SVELKERIRE YLKGHYYVPL
       490        500        510        520        530        540
LRAEETSSPV IGELWSPDQT AEASHVSRYG GSPRDPVLTL RAFAGPLSPA KAEDFRKLWK
       550        560        570        580        590        600
TPPREKAGFL HHVKKSDPER GFERVGRELA HELGYPWVEY WEFLGCFVDL SSQEGLQRLE
       610        620        630        640        650        660
EYLTQQEIGK KAQQETGERE ASCRDKATTS GSNSISVRAF LDEDDMSLEE IKNRQNAARN
       670        680        690        700        710        720
NSPPTVGAFG HTRCSAFPLE QEADLIEAAE PGGPHSSRNG LCHPLNHSRT LAGKRPKAPR
       730        740        750        760        770        780
GEEAHLPPVS DLTVEFDKLN LQNIGRSVSK TPDESTKTKD QILTSRINAV ERDLLEPSPA
       790        800        810        820        830        840
DQLGNGHRRT ESEMSARIAK MSLSPSSPRH EDQLEVTREP ARRLFLFGEE PSKLDQDVLA
       850        860        870        880        890        900
ALECADVDPH QFPAVHRWKS AVLCYSPSDR QSWPSPAVKG RFKSQLPDLS GPHSYSPGRN
       910        920        930
SVAGSNPAKP GLGSPGRYSP VHGSQLRRMA RLAELAAL

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
Q86XL3-1-unknown	MLWPRL...	1	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q86XL3-1-unknown	MLWPRL...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt66948
Q86XL3-646-unknown	MSLEEI...	646	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt66949
Q86XL3-738-unknown	KLNLQN...	738	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC12768
Q86XL3-738-unknown	KLNLQN...	738	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt142046

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...TVEFDK	737	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC12768
...TVEFDK	737	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt125229
...ELAAL	938	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...ELAAL	938	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt62567

TopFIND

Q86XL3: Ankyrin repeat and LEM domain-containing protein 2

General Information

3

N-termini

2

C-termini

1

Cleavages

0

Substrates

Sequence

Isoforms

Filter Information:

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Physiological Relevance:

Evidence Codes:

Methodology:

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Protein Neighborhood

Domains & Features

3 N-termini - 2 C-termini - 1 Cleavages - 0 Substrates

N-termini

C-termini

Cleavages

Substrates