TopFIND 4.0

Q9NR50: Translation initiation factor eIF-2B subunit gamma

General Information

Protein names
- Translation initiation factor eIF-2B subunit gamma
- eIF-2B GDP-GTP exchange factor subunit gamma
Gene names EIF2B3
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID Q9NR50

7

N-termini

5

C-termini

2

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MEFQAVVMAV GGGSRMTDLT SSIPKPLLPV GNKPLIWYPL NLLERVGFEE VIVVTTRDVQ 
        70         80         90        100        110        120 
KALCAEFKMK MKPDIVCIPD DADMGTADSL RYIYPKLKTD VLVLSCDLIT DVALHEVVDL 
       130        140        150        160        170        180 
FRAYDASLAM LMRKGQDSIE PVPGQKGKKK AVEQRDFIGV DSTGKRLLFM ANEADLDEEL 
       190        200        210        220        230        240 
VIKGSILQKH PRIRFHTGLV DAHLYCLKKY IVDFLMENGS ITSIRSELIP YLVRKQFSSA 
       250        260        270        280        290        300 
SSQQGQEEKE EDLKKKELKS LDIYSFIKEA NTLNLAPYDA CWNACRGDRW EDLSRSQVRC 
       310        320        330        340        350        360 
YVHIMKEGLC SRVSTLGLYM EANRQVPKLL SALCPEEPPV HSSAQIVSKH LVGVDSLIGP 
       370        380        390        400        410        420 
ETQIGEKSSI KRSVIGSSCL IKDRVTITNC LLMNSVTVEE GSNIQGSVIC NNAVIEKGAD 
       430        440        450    
IKDCLIGSGQ RIEAKAKRVN EVIVGNDQLM EI

Isoforms

- Isoform 2 of Translation initiation factor eIF-2B subunit gamma - Isoform 3 of Translation initiation factor eIF-2B subunit gamma

Sequence View

        10         20         30         40         50         60 
MEFQAVVMAV GGGSRMTDLT SSIPKPLLPV GNKPLIWYPL NLLERVGFEE VIVVTTRDVQ 
        70         80         90        100        110        120 
KALCAEFKMK MKPDIVCIPD DADMGTADSL RYIYPKLKTD VLVLSCDLIT DVALHEVVDL 
       130        140        150        160        170        180 
FRAYDASLAM LMRKGQDSIE PVPGQKGKKK AVEQRDFIGV DSTGKRLLFM ANEADLDEEL 
       190        200        210        220        230        240 
VIKGSILQKH PRIRFHTGLV DAHLYCLKKY IVDFLMENGS ITSIRSELIP YLVRKQFSSA 
       250        260        270        280        290        300 
SSQQGQEEKE EDLKKKELKS LDIYSFIKEA NTLNLAPYDA CWNACRGDRW EDLSRSQVRC 
       310        320        330        340        350        360 
YVHIMKEGLC SRVSTLGLYM EANRQVPKLL SALCPEEPPV HSSAQIVSKH LVGVDSLIGP 
       370        380        390        400        410        420 
ETQIGEKSSI KRSVIGSSCL IKDRVTITNC LLMNSVTVEE GSNIQGSVIC NNAVIEKGAD 
       430        440        450    
IKDCLIGSGQ RIEAKAKRVN EVIVGNDQLM EI         10         20         30         40         50         60 
MEFQAVVMAV GGGSRMTDLT SSIPKPLLPV GNKPLIWYPL NLLERVGFEE VIVVTTRDVQ 
        70         80         90        100        110        120 
KALCAEFKMK MKPDIVCIPD DADMGTADSL RYIYPKLKTD VLVLSCDLIT DVALHEVVDL 
       130        140        150        160        170        180 
FRAYDASLAM LMRKGQDSIE PVPGQKGKKK AVEQRDFIGV DSTGKRLLFM ANEADLDEEL 
       190        200        210        220        230        240 
VIKGSILQKH PRIRFHTGLV DAHLYCLKKY IVDFLMENGS ITSIRSELIP YLVRKQFSSA 
       250        260        270        280        290        300 
SSQQGQEEKE EDLKKKELKS LDIYSFIKEA NTLNLAPYDA CWNACRGDRW EDLSRSQVRC 
       310        320        330        340        350        360 
YVHIMKEGLC SRVSTLGLYM EANRQVPKLL SALCPEEPPV HSSAQIVSKH LVGVDSLIGP 
       370        380        390        400        410        420 
ETQIGEKSSI KRSVIGSSCL IKDRVTITNC LLMNSVTVEE GSNIQGSVIC NNAVIEKGAD 
       430        440        450    
IKDCLIGSGQ RIEAKAKRVN EVIVGNDQLM EI



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Protein Neighborhood

Domains & Features

7 N-termini - 5 C-termini - 2 Cleavages - 0 Substrates

N-termini

C-termini

Cleavages

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)