Q63ZY3: KN motif and ankyrin repeat domain-containing protein 2

General Information

Protein names	- KN motif and ankyrin repeat domain-containing protein 2 - Ankyrin repeat domain-containing protein 25 - Matrix-remodeling-associated protein 3 - SRC-1-interacting protein - SIP - SRC-interacting protein - SRC1-interacting protein
Gene names	KANK2
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q63ZY3

2 N-termini

2 C-termini

1 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MAQVLHVPAP FPGTPGPASP PAFPAKDPDP PYSVETPYGY RLDLDFLKYV DDIEKGHTLR
        70         80         90        100        110        120
RVAVQRRPRL SSLPRGPGSW WTSTESLCSN ASGDSRHSAY SYCGRGFYPQ YGALETRGGF
       130        140        150        160        170        180
NPRVERTLLD ARRRLEDQAA TPTGLGSLTP SAAGSTASLV GVGLPPPTPR SSGLSTPVPP
       190        200        210        220        230        240
SAGHLAHVRE QMAGALRKLR QLEEQVKLIP VLQVKLSVLQ EEKRQLTVQL KSQKFLGHPT
       250        260        270        280        290        300
AGRGRSELCL DLPDPPEDPV ALETRSVGTW VRERDLGMPD GEAALAAKVA VLETQLKKAL
       310        320        330        340        350        360
QELQAAQARQ ADPQPQAWPP PDSPVRVDTV RVVEGPREVE VVASTAAGAP AQRAQSLEPY
       370        380        390        400        410        420
GTGLRALAMP GRPESPPVFR SQEVVETMCP VPAAATSNVH MVKKISITER SCDGAAGLPE
       430        440        450        460        470        480
VPAESSSSPP GSEVASLTQP EKSTGRVPTQ EPTHREPTRQ AASQESEEAG GTGGPPAGVR
       490        500        510        520        530        540
SIMKRKEEVA DPTAHRRSLQ FVGVNGGYES SSEDSSTAEN ISDNDSTENE APEPRERVPS
       550        560        570        580        590        600
VAEAPQLRPA GTAAAKTSRQ ECQLSRESQH IPTAEGASGS NTEEEIRMEL SPDLISACLA
       610        620        630        640        650        660
LEKYLDNPNA LTERELKVAY TTVLQEWLRL ACRSDAHPEL VRRHLVTFRA MSARLLDYVV
       670        680        690        700        710        720
NIADSNGNTA LHYSVSHANF PVVQQLLDSG VCKVDKQNRA GYSPIMLTAL ATLKTQDDIE
       730        740        750        760        770        780
TVLQLFRLGN INAKASQAGQ TALMLAVSHG RVDVVKALLA CEADVNVQDD DGSTALMCAC
       790        800        810        820        830        840
EHGHKEIAGL LLAVPSCDIS LTDRDGSTAL MVALDAGQSE IASMLYSRMN IKCSFAPMSD
       850
DESPTSSSAE E

Isoforms

- Isoform 2 of KN motif and ankyrin repeat domain-containing protein 2 - Isoform 3 of KN motif and ankyrin repeat domain-containing protein 2

Sequence View

        10         20         30         40         50         60
MAQVLHVPAP FPGTPGPASP PAFPAKDPDP PYSVETPYGY RLDLDFLKYV DDIEKGHTLR
        70         80         90        100        110        120
RVAVQRRPRL SSLPRGPGSW WTSTESLCSN ASGDSRHSAY SYCGRGFYPQ YGALETRGGF
       130        140        150        160        170        180
NPRVERTLLD ARRRLEDQAA TPTGLGSLTP SAAGSTASLV GVGLPPPTPR SSGLSTPVPP
       190        200        210        220        230        240
SAGHLAHVRE QMAGALRKLR QLEEQVKLIP VLQVKLSVLQ EEKRQLTVQL KSQKFLGHPT
       250        260        270        280        290        300
AGRGRSELCL DLPDPPEDPV ALETRSVGTW VRERDLGMPD GEAALAAKVA VLETQLKKAL
       310        320        330        340        350        360
QELQAAQARQ ADPQPQAWPP PDSPVRVDTV RVVEGPREVE VVASTAAGAP AQRAQSLEPY
       370        380        390        400        410        420
GTGLRALAMP GRPESPPVFR SQEVVETMCP VPAAATSNVH MVKKISITER SCDGAAGLPE
       430        440        450        460        470        480
VPAESSSSPP GSEVASLTQP EKSTGRVPTQ EPTHREPTRQ AASQESEEAG GTGGPPAGVR
       490        500        510        520        530        540
SIMKRKEEVA DPTAHRRSLQ FVGVNGGYES SSEDSSTAEN ISDNDSTENE APEPRERVPS
       550        560        570        580        590        600
VAEAPQLRPA GTAAAKTSRQ ECQLSRESQH IPTAEGASGS NTEEEIRMEL SPDLISACLA
       610        620        630        640        650        660
LEKYLDNPNA LTERELKVAY TTVLQEWLRL ACRSDAHPEL VRRHLVTFRA MSARLLDYVV
       670        680        690        700        710        720
NIADSNGNTA LHYSVSHANF PVVQQLLDSG VCKVDKQNRA GYSPIMLTAL ATLKTQDDIE
       730        740        750        760        770        780
TVLQLFRLGN INAKASQAGQ TALMLAVSHG RVDVVKALLA CEADVNVQDD DGSTALMCAC
       790        800        810        820        830        840
EHGHKEIAGL LLAVPSCDIS LTDRDGSTAL MVALDAGQSE IASMLYSRMN IKCSFAPMSD
       850
DESPTSSSAE E         10         20         30         40         50         60
MAQVLHVPAP FPGTPGPASP PAFPAKDPDP PYSVETPYGY RLDLDFLKYV DDIEKGHTLR
        70         80         90        100        110        120
RVAVQRRPRL SSLPRGPGSW WTSTESLCSN ASGDSRHSAY SYCGRGFYPQ YGALETRGGF
       130        140        150        160        170        180
NPRVERTLLD ARRRLEDQAA TPTGLGSLTP SAAGSTASLV GVGLPPPTPR SSGLSTPVPP
       190        200        210        220        230        240
SAGHLAHVRE QMAGALRKLR QLEEQVKLIP VLQVKLSVLQ EEKRQLTVQL KSQKFLGHPT
       250        260        270        280        290        300
AGRGRSELCL DLPDPPEDPV ALETRSVGTW VRERDLGMPD GEAALAAKVA VLETQLKKAL
       310        320        330        340        350        360
QELQAAQARQ ADPQPQAWPP PDSPVRVDTV RVVEGPREVE VVASTAAGAP AQRAQSLEPY
       370        380        390        400        410        420
GTGLRALAMP GRPESPPVFR SQEVVETMCP VPAAATSNVH MVKKISITER SCDGAAGLPE
       430        440        450        460        470        480
VPAESSSSPP GSEVASLTQP EKSTGRVPTQ EPTHREPTRQ AASQESEEAG GTGGPPAGVR
       490        500        510        520        530        540
SIMKRKEEVA DPTAHRRSLQ FVGVNGGYES SSEDSSTAEN ISDNDSTENE APEPRERVPS
       550        560        570        580        590        600
VAEAPQLRPA GTAAAKTSRQ ECQLSRESQH IPTAEGASGS NTEEEIRMEL SPDLISACLA
       610        620        630        640        650        660
LEKYLDNPNA LTERELKVAY TTVLQEWLRL ACRSDAHPEL VRRHLVTFRA MSARLLDYVV
       670        680        690        700        710        720
NIADSNGNTA LHYSVSHANF PVVQQLLDSG VCKVDKQNRA GYSPIMLTAL ATLKTQDDIE
       730        740        750        760        770        780
TVLQLFRLGN INAKASQAGQ TALMLAVSHG RVDVVKALLA CEADVNVQDD DGSTALMCAC
       790        800        810        820        830        840
EHGHKEIAGL LLAVPSCDIS LTDRDGSTAL MVALDAGQSE IASMLYSRMN IKCSFAPMSD
       850
DESPTSSSAE E

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
Q63ZY3-1-unknown	MAQVLH...	1	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q63ZY3-1-unknown	MAQVLH...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt78538
Q63ZY3-1-unknown	MAQVLH...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt78539
Q63ZY3-506-unknown	GGYESS...	506	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC12544
Q63ZY3-506-unknown	GGYESS...	506	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt153482
Q63ZY3-506-unknown	GGYESS...	506	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt153572

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...FVGVNG	505	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC12544
...FVGVNG	505	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt136905
...FVGVNG	505	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt136994
...SSAEE	851	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...SSAEE	851	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt74156

TopFIND

Q63ZY3: KN motif and ankyrin repeat domain-containing protein 2

General Information

2

N-termini

2

C-termini

1

Cleavages

0

Substrates

Sequence

Isoforms

Filter Information:

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

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Protease Assignment Confidence:

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Protein Neighborhood

Domains & Features

2 N-termini - 2 C-termini - 1 Cleavages - 0 Substrates

N-termini

C-termini

Cleavages

Substrates