TopFIND 4.0

P42285: Exosome RNA helicase MTR4 {ECO:0000305}

General Information

Protein names
- Exosome RNA helicase MTR4 {ECO:0000305}
- 3.6.4.13
- ATP-dependent RNA helicase DOB1 {ECO:0000303|PubMed:16782053}
- ATP-dependent RNA helicase SKIV2L2
- Superkiller viralicidic activity 2-like 2
- TRAMP-like complex helicase
Gene names SKIV2L2
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID P42285

6

N-termini

3

C-termini

2

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MADAFGDELF SVFEGDSTTA AGTKKDKEKD KGKWKGPPGS ADKAGKRFDG KLQSESTNNG 
        70         80         90        100        110        120 
KNKRDVDFEG TDEPIFGKKP RIEESITEDL SLADLMPRVK VQSVETVEGC THEVALPAEE 
       130        140        150        160        170        180 
DYLPLKPRVG KAAKEYPFIL DAFQREAIQC VDNNQSVLVS AHTSAGKTVC AEYAIALALR 
       190        200        210        220        230        240 
EKQRVIFTSP IKALSNQKYR EMYEEFQDVG LMTGDVTINP TASCLVMTTE ILRSMLYRGS 
       250        260        270        280        290        300 
EVMREVAWVI FDEIHYMRDS ERGVVWEETI ILLPDNVHYV FLSATIPNAR QFAEWICHLH 
       310        320        330        340        350        360 
KQPCHVIYTD YRPTPLQHYI FPAGGDGLHL VVDENGDFRE DNFNTAMQVL RDAGDLAKGD 
       370        380        390        400        410        420 
QKGRKGGTKG PSNVFKIVKM IMERNFQPVI IFSFSKKDCE AYALQMTKLD FNTDEEKKMV 
       430        440        450        460        470        480 
EEVFSNAIDC LSDEDKKLPQ VEHVLPLLKR GIGIHHGGLL PILKETIEIL FSEGLIKALF 
       490        500        510        520        530        540 
ATETFAMGIN MPARTVLFTN ARKFDGKDFR WISSGEYIQM SGRAGRRGMD DRGIVILMVD 
       550        560        570        580        590        600 
EKMSPTIGKQ LLKGSADPLN SAFHLTYNMV LNLLRVEEIN PEYMLEKSFY QFQHYRAIPG 
       610        620        630        640        650        660 
VVEKVKNSEE QYNKIVIPNE ESVVIYYKIR QQLAKLGKEI EEYIHKPKYC LPFLQPGRLV 
       670        680        690        700        710        720 
KVKNEGDDFG WGVVVNFSKK SNVKPNSGEL DPLYVVEVLL RCSKESLKNS ATEAAKPAKP 
       730        740        750        760        770        780 
DEKGEMQVVP VLVHLLSAIS SVRLYIPKDL RPVDNRQSVL KSIQEVQKRF PDGIPLLDPI 
       790        800        810        820        830        840 
DDMGIQDQGL KKVIQKVEAF EHRMYSHPLH NDPNLETVYT LCEKKAQIAI DIKSAKRELK 
       850        860        870        880        890        900 
KARTVLQMDE LKCRKRVLRR LGFATSSDVI EMKGRVACEI SSADELLLTE MMFNGLFNDL 
       910        920        930        940        950        960 
SAEQATALLS CFVFQENSSE MPKLTEQLAG PLRQMQECAK RIAKVSAEAK LEIDEETYLS 
       970        980        990       1000       1010       1020 
SFKPHLMDVV YTWATGATFA HICKMTDVFE GSIIRCMRRL EELLRQMCQA AKAIGNTELE 
      1030       1040    
NKFAEGITKI KRDIVFAASL YL

Isoforms



Sequence View



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Protein Neighborhood

Domains & Features

6 N-termini - 3 C-termini - 2 Cleavages - 0 Substrates

N-termini

C-termini

Cleavages

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)