Q99426: Tubulin-folding cofactor B

General Information

Protein names	- Tubulin-folding cofactor B - Cytoskeleton-associated protein 1 - Cytoskeleton-associated protein CKAPI - Tubulin-specific chaperone B
Gene names	TBCB
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q99426

4 N-termini

3 C-termini

1 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MEVTGVSAPT VTVFISSSLN TFRSEKRYSR SLTIAEFKCK LELLVGSPAS CMELELYGVD
        70         80         90        100        110        120
DKFYSKLDQE DALLGSYPVD DGCRIHVIDH SGARLGEYED VSRVEKYTIS QEAYDQRQDT
       130        140        150        160        170        180
VRSFLKRSKL GRYNEEERAQ QEAEAAQRLA EEKAQASSIP VGSRCEVRAA GQSPRRGTVM
       190        200        210        220        230        240
YVGLTDFKPG YWIGVRYDEP LGKNDGSVNG KRYFECQAKY GAFVKPAVVT VGDFPEEDYG

LDEI

Isoforms

- Isoform 2 of Tubulin-folding cofactor B

Sequence View

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Physiological Relevance:

Evidence Codes:

Methodology:

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Biological System:

Protease Assignment Confidence:

Evidence Names:

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Protein Neighborhood

Domains & Features

4 N-termini - 3 C-termini - 1 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name
Q99426-1-Acetylation	MEVTGV...	1	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q99426-1-Acetylation	MEVTGV...	1	acetylation-		other		CNRS/ISV	Large_scale_NTA_Human
Q99426-18-unknown	SLNTFR...	18		inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000465979
Q99426-52-unknown	MELELY...	52		inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000467172
Q99426-52-unknown	MELELY...	52		inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000467487
Q99426-52-unknown	MELELY...	52		inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000468055
Q99426-113-unknown	AYDQRQ...	113		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC13128

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...TISQEA	112	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC13128
...CQAKYG	220	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000467172
...GLDEI	244	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
GRAB_HUMAN	112	SQEA.\|.AYDQ	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:Complementary positional proteo... (M14.017)	20526345,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)