Q15021: Condensin complex subunit 1

General Information

Protein names	- Condensin complex subunit 1 - Chromosome condensation-related SMC-associated protein 1 - Chromosome-associated protein D2 - hCAP-D2 - Non-SMC condensin I complex subunit D2 - XCAP-D2 homolog
Gene names	NCAPD2
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q15021

3 N-termini

5 C-termini

2 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MAPQMYEFHL PLSPEELLKS GGVNQYVVQE VLSIKHLPPQ LRAFQAAFRA QGPLAMLQHF
        70         80         90        100        110        120
DTIYSILHHF RSIDPGLKED TLQFLIKVVS RHSQELPAIL DDTTLSGSDR NAHLNALKMN
       130        140        150        160        170        180
CYALIRLLES FETMASQTNL VDLDLGGKGK KARTKAAHGF DWEEERQPIL QLLTQLLQLD
       190        200        210        220        230        240
IRHLWNHSII EEEFVSLVTG CCYRLLENPT INHQKNRPTR EAITHLLGVA LTRYNHMLSA
       250        260        270        280        290        300
TVKIIQMLQH FEHLAPVLVA AVSLWATDYG MKSIVGEIVR EIGQKCPQEL SRDPSGTKGF
       310        320        330        340        350        360
AAFLTELAER VPAILMSSMC ILLDHLDGEN YMMRNAVLAA MAEMVLQVLS GDQLEAAARD
       370        380        390        400        410        420
TRDQFLDTLQ AHGHDVNSFV RSRVLQLFTR IVQQKALPLT RFQAVVALAV GRLADKSVLV
       430        440        450        460        470        480
CKNAIQLLAS FLANNPFSCK LSDADLAGPL QKETQKLQEM RAQRRTAAAS AVLDPEEEWE
       490        500        510        520        530        540
AMLPELKSTL QQLLQLPQGE EEIPEQIANT ETTEDVKGRI YQLLAKASYK KAIILTREAT
       550        560        570        580        590        600
GHFQESEPFS HIDPEESEET RLLNILGLIF KGPAASTQEK NPRESTGNMV TGQTVCKNKP
       610        620        630        640        650        660
NMSDPEESRG NDELVKQEML VQYLQDAYSF SRKITEAIGI ISKMMYENTT TVVQEVIEFF
       670        680        690        700        710        720
VMVFQFGVPQ ALFGVRRMLP LIWSKEPGVR EAVLNAYRQL YLNPKGDSAR AKAQALIQNL
       730        740        750        760        770        780
SLLLVDASVG TIQCLEEILC EFVQKDELKP AVTQLLWERA TEKVACCPLE RCSSVMLLGM
       790        800        810        820        830        840
MARGKPEIVG SNLDTLVSIG LDEKFPQDYR LAQQVCHAIA NISDRRKPSL GKRHPPFRLP
       850        860        870        880        890        900
QEHRLFERLR ETVTKGFVHP DPLWIPFKEV AVTLIYQLAE GPEVICAQIL QGCAKQALEK
       910        920        930        940        950        960
LEEKRTSQED PKESPAMLPT FLLMNLLSLA GDVALQQLVH LEQAVSGELC RRRVLREEQE
       970        980        990       1000       1010       1020
HKTKDPKEKN TSSETTMEEE LGLVGATADD TEAELIRGIC EMELLDGKQT LAAFVPLLLK
      1030       1040       1050       1060       1070       1080
VCNNPGLYSN PDLSAAASLA LGKFCMISAT FCDSQLRLLF TMLEKSPLPI VRSNLMVATG
      1090       1100       1110       1120       1130       1140
DLAIRFPNLV DPWTPHLYAR LRDPAQQVRK TAGLVMTHLI LKDMVKVKGQ VSEMAVLLID
      1150       1160       1170       1180       1190       1200
PEPQIAALAK NFFNELSHKG NAIYNLLPDI ISRLSDPELG VEEEPFHTIM KQLLSYITKD
      1210       1220       1230       1240       1250       1260
KQTESLVEKL CQRFRTSRTE RQQRDLAYCV SQLPLTERGL RKMLDNFDCF GDKLSDESIF
      1270       1280       1290       1300       1310       1320
SAFLSVVGKL RRGAKPEGKA IIDEFEQKLR ACHTRGLDGI KELEIGQAGS QRAPSAKKPS
      1330       1340       1350       1360       1370       1380
TGSRYQPLAS TASDNDFVTP EPRRTTRRHP NTQQRASKKK PKVVFSSDES SEEDLSAEMT
      1390       1400
EDETPKKTTP ILRASARRHR S

Isoforms

Sequence View

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Evidence Names:

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Protein Neighborhood

Domains & Features

3 N-termini - 5 C-termini - 2 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
Q15021-1-unknown	MAPQMY...	1	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q15021-1329-unknown	ASTASD...	1329	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC14519
Q15021-1335-unknown	NDFVTP...	1335	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC12334

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...LNALKM	118	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000444377
...KFCMIS	1047	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000371895
...RYQPLA	1328	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC14519
...STASDN	1334	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC12334
...RRHRS	1401	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
GRAM_HUMAN	1328	QPLA.\|.ASTA	inferred from experiment	unknown	MEROPS	Bovenschen N	de Poot SA et al.:Human and mouse granzyme M disp... (S01.139)	21564021,
GRAB_HUMAN	1334	ASDN.\|.NDFV	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:Complementary positional proteo... (M14.017)	20526345,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)