Q8NFY9: Kelch repeat and BTB domain-containing protein 8

General Information

Protein names	- Kelch repeat and BTB domain-containing protein 8 - T-cell activation kelch repeat protein - TA-KRP
Gene names	KBTBD8
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q8NFY9

4 N-termini

4 C-termini

1 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MAASADLSKS SPTPNGIPSS DPASDAMDPF HACSILKQLK TMYDEGQLTD IVVEVDHGKT
        70         80         90        100        110        120
FSCHRNVLAA ISPYFRSMFT SGLTESTQKE VRIVGVEAES MDLVLNYAYT SRVILTEANV
       130        140        150        160        170        180
QALFTAASIF QIPSIQDQCA KYMISHLDPQ NSIGVFIFAD HYGHQELGDR SKEYIRKKFL
       190        200        210        220        230        240
CVTKEQEFLQ LTKDQLISIL DSDDLNVDRE EHVYESIIRW FEHEQNEREV HLPEIFAKCI
       250        260        270        280        290        300
RFPLMEDTFI EKIPPQFAQA IAKSCVEKGP SNTNGCTQRL GMTASEMIIC FDAAHKHSGK
       310        320        330        340        350        360
KQTVPCLDIV TGRVFKLCKP PNDLREVGIL VSPDNDIYIA GGYRPSSSEV SIDHKAENDF
       370        380        390        400        410        420
WMYDHSTNRW LSKPSLLRAR IGCKLVYCCG KMYAIGGRVY EGDGRNSLKS VECYDSRENC
       430        440        450        460        470        480
WTTVCAMPVA MEFHNAVEYK EKIYVLQGEF FLFYEPQKDY WGFLTPMTVP RIQGLAAVYK
       490        500        510        520        530        540
DSIYYIAGTC GNHQRMFTVE AYDIELNKWT RKKDFPCDQS INPYLKLVLF QNKLHLFVRA
       550        560        570        580        590        600
TQVTVEEHVF RTSRKNSLYQ YDDIADQWMK VYETPDRLWD LGRHFECAVA KLYPQCLQKV

L

Isoforms

- Isoform 2 of Kelch repeat and BTB domain-containing protein 8

Sequence View

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Protein Neighborhood

Domains & Features

4 N-termini - 4 C-termini - 1 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
Q8NFY9-1-unknown	MAASAD...	1	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q8NFY9-27-unknown	MDPFHA...	27	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000418075
Q8NFY9-27-unknown	MDPFHA...	27	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000295568
Q8NFY9-78-unknown	MFTSGL...	78	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000417341
Q8NFY9-335-unknown	NDIYIA...	335	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC12914

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...GDRSKE	172	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000418075
...CIRFPL	243	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000417341
...LVSPDN	334	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC12914
...LQKVL	601	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
GRAB_HUMAN	334	SPDN.\|.NDIY	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:Analysis of protein processing ... (S01.010)	18836177,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)