TopFIND 4.0

Q9BXV9: EKC/KEOPS complex subunit GON7 {ECO:0000305}

General Information

Protein names	- EKC/KEOPS complex subunit GON7 {ECO:0000305}
Gene names	C14orf142
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q9BXV9

3

N-termini

3

C-termini

2

Cleavages

0

Substrates

Sequence

10 20 30 40 50 60
MELLGEYVGQ EGKPQKLRVS CEAPGDGDPF QGLLSGVAQM KDMVTELFDP LVQGEVQHRV
70 80 90 100
AAAPDEDLDG DDEDDAEDEN NIDNRTNFDG PSAKRPKTPS

Isoforms

Sequence View

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Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

3 N-termini - 3 C-termini - 2 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q9BXV9-1-Acetylation	MELLGE...	1	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q9BXV9-1-Acetylation	MELLGE...	1	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345
Q9BXV9-1-Acetylation	MELLGE...	1	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345
Q9BXV9-6-unknown	EYVGQE...	6		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC6755
Q9BXV9-72-unknown	DEDDAE...	72		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC13254

C-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
	...MELLGE	5	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC6755
	...DLDGDD	71	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC13254
	...PKTPS	100	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
	...PKTPS	100		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345,

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
CATL1_HUMAN	5	LLGE.\|.EYVG	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,
GRAB_HUMAN	71	DGDD.\|.DEDD	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:Complementary positional proteo... (M14.017)	20526345,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)