Q12872: Splicing factor, suppressor of white-apricot homolog
Protein names | - Splicing factor, suppressor of white-apricot homolog - Splicing factor, arginine/serine-rich 8 - Suppressor of white apricot protein homolog |
---|---|
Gene names | SFSWAP |
Organism | Homo sapiens |
Protease Family | |
Protease ID | |
Chromosome location | |
UniProt ID | Q12872 |
8
N-termini
3
C-termini
1
Cleavages
0
Substrates
Sequence
10 20 30 40 50 60
MYGASGGRAK PERKSGAKEE AGPGGAGGGG SRVELLVFGY ACKLFRDDER ALAQEQGQHL
70 80 90 100 110 120
IPWMGDHKIL IDRYDGRGHL HDLSEYDAEY STWNRDYQLS EEEARIEALC DEERYLALHT
130 140 150 160 170 180
DLLEEEARQE EEYKRLSEAL AEDGSYNAVG FTYGSDYYDP SEPTEEEEPS KQREKNEAEN
190 200 210 220 230 240
LEENEEPFVA PLGLSVPSDV ELPPTAKMHA IIERTASFVC RQGAQFEIML KAKQARNSQF
250 260 270 280 290 300
DFLRFDHYLN PYYKFIQKAM KEGRYTVLAE NKSDEKKKSG VSSDNEDDDD EEDGNYLHPS
310 320 330 340 350 360
LFASKKCNRL EELMKPLKVV DPDHPLAALV RKAQADSSTP TPHNADGAPV QPSQVEYTAD
370 380 390 400 410 420
STVAAMYYSY YMLPDGTYCL APPPPGIDVT TYYSTLPAGV TVSNSPGVTT TAPPPPGTTP
430 440 450 460 470 480
LPPPTTAETS SGATSTTTTT SALAPVAAII PPPPDVQPVI DKLAEYVARN GLKFETSVRA
490 500 510 520 530 540
KNDQRFEFLQ PWHQYNAYYE FKKQFFLQKE GGDSMQAVSA PEEAPTDSAP EKPSDAGEDG
550 560 570 580 590 600
APEDAAEVGA RAGSGGKKEA SSSKTVPDGK LVKASFAPIS FAIKAKENDL LPLEKNRVKL
610 620 630 640 650 660
DDDSDDDEES KEGQESSSSA ANTNPAVAPP CVVVEEKKPQ LTQEELEAKQ AKQKLEDRLA
670 680 690 700 710 720
AAAREKLAQA SKESKEKQLQ AERKRKAALF LQTLKNPLPE AEAGKIEESP FSVEESSTTP
730 740 750 760 770 780
CPLLTGGRPL PTLEVKPPDR PSSKSKDPPR EEEKEKKKKK HKKRSRTRSR SPKYHSSSKS
790 800 810 820 830 840
RSRSHSKAKH SLPSAYRTVR RSRSRSRSPR RRAHSPERRR EERSVPTAYR VSRSPGASRK
850 860 870 880 890 900
RTRSRSPHEK KKKRRSRSRT KSKARSQSVS PSKQAAPRPA APAAHSAHSA SVSPVESRGS
910 920 930 940 950
SQERSRGVSQ EKEAQISSAI VSSVQSKITQ DLMAKVRAML AASKNLQTSA S
Isoforms
- Isoform 2 of Splicing factor, suppressor of white-apricot homologSequence View
10 20 30 40 50 60
MYGASGGRAK PERKSGAKEE AGPGGAGGGG SRVELLVFGY ACKLFRDDER ALAQEQGQHL
70 80 90 100 110 120
IPWMGDHKIL IDRYDGRGHL HDLSEYDAEY STWNRDYQLS EEEARIEALC DEERYLALHT
130 140 150 160 170 180
DLLEEEARQE EEYKRLSEAL AEDGSYNAVG FTYGSDYYDP SEPTEEEEPS KQREKNEAEN
190 200 210 220 230 240
LEENEEPFVA PLGLSVPSDV ELPPTAKMHA IIERTASFVC RQGAQFEIML KAKQARNSQF
250 260 270 280 290 300
DFLRFDHYLN PYYKFIQKAM KEGRYTVLAE NKSDEKKKSG VSSDNEDDDD EEDGNYLHPS
310 320 330 340 350 360
LFASKKCNRL EELMKPLKVV DPDHPLAALV RKAQADSSTP TPHNADGAPV QPSQVEYTAD
370 380 390 400 410 420
STVAAMYYSY YMLPDGTYCL APPPPGIDVT TYYSTLPAGV TVSNSPGVTT TAPPPPGTTP
430 440 450 460 470 480
LPPPTTAETS SGATSTTTTT SALAPVAAII PPPPDVQPVI DKLAEYVARN GLKFETSVRA
490 500 510 520 530 540
KNDQRFEFLQ PWHQYNAYYE FKKQFFLQKE GGDSMQAVSA PEEAPTDSAP EKPSDAGEDG
550 560 570 580 590 600
APEDAAEVGA RAGSGGKKEA SSSKTVPDGK LVKASFAPIS FAIKAKENDL LPLEKNRVKL
610 620 630 640 650 660
DDDSDDDEES KEGQESSSSA ANTNPAVAPP CVVVEEKKPQ LTQEELEAKQ AKQKLEDRLA
670 680 690 700 710 720
AAAREKLAQA SKESKEKQLQ AERKRKAALF LQTLKNPLPE AEAGKIEESP FSVEESSTTP
730 740 750 760 770 780
CPLLTGGRPL PTLEVKPPDR PSSKSKDPPR EEEKEKKKKK HKKRSRTRSR SPKYHSSSKS
790 800 810 820 830 840
RSRSHSKAKH SLPSAYRTVR RSRSRSRSPR RRAHSPERRR EERSVPTAYR VSRSPGASRK
850 860 870 880 890 900
RTRSRSPHEK KKKRRSRSRT KSKARSQSVS PSKQAAPRPA APAAHSAHSA SVSPVESRGS
910 920 930 940 950
SQERSRGVSQ EKEAQISSAI VSSVQSKITQ DLMAKVRAML AASKNLQTSA S
Protein Neighborhood
Domains & Features
8 N-termini - 3 C-termini - 1 Cleavages - 0 Substrates
N-termini
Name | Sequence | Position | Modification | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMID) |
---|---|---|---|---|---|---|---|---|---|
Q12872-1-unknown | MYGASG... | 1 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
Q12872-1-unknown | MYGASG... | 1 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt89412 | |||
Q12872-157-unknown | YYDPSE... | 157 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC11958 | |||
Q12872-157-unknown | YYDPSE... | 157 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt145047 | |||
Q12872-528-unknown | SAPEKP... | 528 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt174018 | |||
Q12872-528- | SAPEKP... | 528 | Subtiligase Based Positive Selection | Wells | apoptotic_Jurkat_staurotrail | 23264352 | |||
Q12872-528- | SAPEKP... | 528 | Subtiligase Based Positive Selection | Wells | apoptotic_MM1s_bort | 23264352 | |||
Q12872-528- | SAPEKP... | 528 | Subtiligase Based Positive Selection | Wells | apoptotic_MM1SDBJurkat_Mix | 23264352 | |||
Q12872-575- | SFAPIS... | 575 | Subtiligase Based Positive Selection | Wells | DB_Untreated | 23264352 | |||
Q12872-575-unknown | SFAPIS... | 575 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt164751 | |||
Q12872-582-unknown | AIKAKE... | 582 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt168241 | |||
Q12872-582- | AIKAKE... | 582 | Subtiligase Based Positive Selection | Wells | apoptotic_Jurkat_bortezomib | 23264352 | |||
Q12872-582- | AIKAKE... | 582 | Subtiligase Based Positive Selection | Wells | apoptosis_U266_bortezomib_induced | 23264352 |
C-termini
Cleavages
Protease | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
---|---|---|---|---|---|---|---|---|
GRAB_HUMAN | 156 | GSDY.|.YYDP | inferred from experiment | unknown | MEROPS | Gevaert K | Van Damme P et al.:Complementary positional proteo... (M14.017) | 20526345, |
Substrates
Substrate | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
---|