Q9UBU9: Nuclear RNA export factor 1

General Information

Protein names	- Nuclear RNA export factor 1 - Tip-associated protein - Tip-associating protein - mRNA export factor TAP
Gene names	NXF1
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q9UBU9

4 N-termini

2 C-termini

1 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MADEGKSYSE HDDERVNFPQ RKKKGRGPFR WKYGEGNRRS GRGGSGIRSS RLEEDDGDVA
        70         80         90        100        110        120
MSDAQDGPRV RYNPYTTRPN RRGDTWHDRD RIHVTVRRDR APPERGGAGT SQDGTSKNWF
       130        140        150        160        170        180
KITIPYGRKY DKAWLLSMIQ SKCSVPFTPI EFHYENTRAQ FFVEDASTAS ALKAVNYKIL
       190        200        210        220        230        240
DRENRRISII INSSAPPHTI LNELKPEQVE QLKLIMSKRY DGSQQALDLK GLRSDPDLVA
       250        260        270        280        290        300
QNIDVVLNRR SCMAATLRII EENIPELLSL NLSNNRLYRL DDMSSIVQKA PNLKILNLSG
       310        320        330        340        350        360
NELKSERELD KIKGLKLEEL WLDGNSLCDT FRDQSTYISA IRERFPKLLR LDGHELPPPI
       370        380        390        400        410        420
AFDVEAPTTL PPCKGSYFGT ENLKSLVLHF LQQYYAIYDS GDRQGLLDAY HDGACCSLSI
       430        440        450        460        470        480
PFIPQNPARS SLAEYFKDSR NVKKLKDPTL RFRLLKHTRL NVVAFLNELP KTQHDVNSFV
       490        500        510        520        530        540
VDISAQTSTL LCFSVNGVFK EVDGKSRDSL RAFTRTFIAV PASNSGLCIV NDELFVRNAS
       550        560        570        580        590        600
SEEIQRAFAM PAPTPSSSPV PTLSPEQQEM LQAFSTQSGM NLEWSQKCLQ DNNWDYTRSA
       610
QAFTHLKAKG EIPEVAFMK

Isoforms

- Isoform 2 of Nuclear RNA export factor 1

Sequence View

Protein Neighborhood

Domains & Features

4 N-termini - 2 C-termini - 1 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Evidence name
Q9UBU9-2-unknown	MADEGK...	1		inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q9UBU9-1-unknown	MADEGK...	1		inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt83583
Q9UBU9-2-Acetylation	ADEGKS...	2	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q9UBU9-2-Acetylation	ADEGKS...	2	acetylation-	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt110048
Q9UBU9-56-unknown	DGDVAM...	56		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC13499
Q9UBU9-56-unknown	DGDVAM...	56		inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt139614

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...RLEEDD	55	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC13499
...RLEEDD	55	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt122709
...VAFMK	619	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
GRAB_HUMAN	55	EEDD.\|.DGDV	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:Complementary positional proteo... (M14.017)	20526345,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

TopFIND

Q9UBU9: Nuclear RNA export factor 1

General Information

4

N-termini

2

C-termini

1

Cleavages

0

Substrates

Sequence

Isoforms

Filter Information:

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

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Protein Neighborhood

Domains & Features

4 N-termini - 2 C-termini - 1 Cleavages - 0 Substrates

N-termini

C-termini

Cleavages

Substrates