P35658: Nuclear pore complex protein Nup214
Protein names | - Nuclear pore complex protein Nup214 - 214 kDa nucleoporin - Nucleoporin Nup214 - Protein CAN |
---|---|
Gene names | NUP214 |
Organism | Homo sapiens |
Protease Family | |
Protease ID | |
Chromosome location | |
UniProt ID | P35658 |
15
N-termini
3
C-termini
2
Cleavages
0
Substrates
Sequence
10 20 30 40 50 60
MGDEMDAMIP EREMKDFQFR ALKKVRIFDS PEELPKERSS LLAVSNKYGL VFAGGASGLQ
70 80 90 100 110 120
IFPTKNLLIQ NKPGDDPNKI VDKVQGLLVP MKFPIHHLAL SCDNLTLSAC MMSSEYGSII
130 140 150 160 170 180
AFFDVRTFSN EAKQQKRPFA YHKLLKDAGG MVIDMKWNPT VPSMVAVCLA DGSIAVLQVT
190 200 210 220 230 240
ETVKVCATLP STVAVTSVCW SPKGKQLAVG KQNGTVVQYL PTLQEKKVIP CPPFYESDHP
250 260 270 280 290 300
VRVLDVLWIG TYVFAIVYAA ADGTLETSPD VVMALLPKKE EKHPEIFVNF MEPCYGSCTE
310 320 330 340 350 360
RQHHYYLSYI EEWDLVLAAS AASTEVSILA RQSDQINWES WLLEDSSRAE LPVTDKSDDS
370 380 390 400 410 420
LPMGVVVDYT NQVEITISDE KTLPPAPVLM LLSTDGVLCP FYMINQNPGV KSLIKTPERL
430 440 450 460 470 480
SLEGERQPKS PGSTPTTPTS SQAPQKLDAS AAAAPASLPP SSPAAPIATF SLLPAGGAPT
490 500 510 520 530 540
VFSFGSSSLK SSATVTGEPP SYSSGSDSSK AAPGPGPSTF SFVPPSKASL APTPAASPVA
550 560 570 580 590 600
PSAASFSFGS SGFKPTLEST PVPSVSAPNI AMKPSFPPST SAVKVNLSEK FTAAATSTPV
610 620 630 640 650 660
SSSQSAPPMS PFSSASKPAA SGPLSHPTPL SAPPSSVPLK SSVLPSPSGR SAQGSSSPVP
670 680 690 700 710 720
SMVQKSPRIT PPAAKPGSPQ AKSLQPAVAE KQGHQWKDSD PVMAGIGEEI AHFQKELEEL
730 740 750 760 770 780
KARTSKACFQ VGTSEEMKML RTESDDLHTF LLEIKETTES LHGDISSLKT TLLEGFAGVE
790 800 810 820 830 840
EAREQNERNR DSGYLHLLYK RPLDPKSEAQ LQEIRRLHQY VKFAVQDVND VLDLEWDQHL
850 860 870 880 890 900
EQKKKQRHLL VPERETLFNT LANNREIINQ QRKRLNHLVD SLQQLRLYKQ TSLWSLSSAV
910 920 930 940 950 960
PSQSSIHSFD SDLESLCNAL LKTTIESHTK SLPKVPAKLS PMKQAQLRNF LAKRKTPPVR
970 980 990 1000 1010 1020
STAPASLSRS AFLSQRYYED LDEVSSTSSV SQSLESEDAR TSCKDDEAVV QAPRHAPVVR
1030 1040 1050 1060 1070 1080
TPSIQPSLLP HAAPFAKSHL VHGSSPGVMG TSVATSASKI IPQGADSTML ATKTVKHGAP
1090 1100 1110 1120 1130 1140
SPSHPISAPQ AAAAAALRRQ MASQAPAVNT LTESTLKNVP QVVNVQELKN NPATPSTAMG
1150 1160 1170 1180 1190 1200
SSVPYSTAKT PHPVLTPVAA NQAKQGSLIN SLKPSGPTPA SGQLSSGDKA SGTAKIETAV
1210 1220 1230 1240 1250 1260
TSTPSASGQF SKPFSFSPSG TGFNFGIITP TPSSNFTAAQ GATPSTKESS QPDAFSSGGG
1270 1280 1290 1300 1310 1320
SKPSYEAIPE SSPPSGITSA SNTTPGEPAA SSSRPVAPSG TALSTTSSKL ETPPSKLGEL
1330 1340 1350 1360 1370 1380
LFPSSLAGET LGSFSGLRVG QADDSTKPTN KASSTSLTST QPTKTSGVPS GFNFTAPPVL
1390 1400 1410 1420 1430 1440
GKHTEPPVTS SATTTSVAPP AATSTSSTAV FGSLPVTSAG SSGVISFGGT SLSAGKTSFS
1450 1460 1470 1480 1490 1500
FGSQQTNSTV PPSAPPPTTA ATPLPTSFPT LSFGSLLSSA TTPSLPMSAG RSTEEATSSA
1510 1520 1530 1540 1550 1560
LPEKPGDSEV SASAASLLEE QQSAQLPQAP PQTSDSVKKE PVLAQPAVSN SGTAASSTSL
1570 1580 1590 1600 1610 1620
VALSAEATPA TTGVPDARTE AVPPASSFSV PGQTAVTAAA ISSAGPVAVE TSSTPIASST
1630 1640 1650 1660 1670 1680
TSIVAPGPSA EAAAFGTVTS GSSVFAQPPA ASSSSAFNQL TNNTATAPSA TPVFGQVAAS
1690 1700 1710 1720 1730 1740
TAPSLFGQQT GSTASTAAAT PQVSSSGFSS PAFGTTAPGV FGQTTFGQAS VFGQSASSAA
1750 1760 1770 1780 1790 1800
SVFSFSQPGF SSVPAFGQPA SSTPTSTSGS VFGAASSTSS SSSFSFGQSS PNTGGGLFGQ
1810 1820 1830 1840 1850 1860
SNAPAFGQSP GFGQGGSVFG GTSAATTTAA TSGFSFCQAS GFGSSNTGSV FGQAASTGGI
1870 1880 1890 1900 1910 1920
VFGQQSSSSS GSVFGSGNTG RGGGFFSGLG GKPSQDAANK NPFSSASGGF GSTATSNTSN
1930 1940 1950 1960 1970 1980
LFGNSGAKTF GGFASSSFGE QKPTGTFSSG GGSVASQGFG FSSPNKTGGF GAAPVFGSPP
1990 2000 2010 2020 2030 2040
TFGGSPGFGG VPAFGSAPAF TSPLGSTGGK VFGEGTAAAS AGGFGFGSSS NTTSFGTLAS
2050 2060 2070 2080 2090
QNAPTFGSLS QQTSGFGTQS SGFSGFGSGT GGFSFGSNNS SVQGFGGWRS
Isoforms
- Isoform 2 of Nuclear pore complex protein Nup214 - Isoform 3 of Nuclear pore complex protein Nup214 - Isoform 4 of Nuclear pore complex protein Nup214 - Isoform 5 of Nuclear pore complex protein Nup214Sequence View
10 20 30 40 50 60
MGDEMDAMIP EREMKDFQFR ALKKVRIFDS PEELPKERSS LLAVSNKYGL VFAGGASGLQ
70 80 90 100 110 120
IFPTKNLLIQ NKPGDDPNKI VDKVQGLLVP MKFPIHHLAL SCDNLTLSAC MMSSEYGSII
130 140 150 160 170 180
AFFDVRTFSN EAKQQKRPFA YHKLLKDAGG MVIDMKWNPT VPSMVAVCLA DGSIAVLQVT
190 200 210 220 230 240
ETVKVCATLP STVAVTSVCW SPKGKQLAVG KQNGTVVQYL PTLQEKKVIP CPPFYESDHP
250 260 270 280 290 300
VRVLDVLWIG TYVFAIVYAA ADGTLETSPD VVMALLPKKE EKHPEIFVNF MEPCYGSCTE
310 320 330 340 350 360
RQHHYYLSYI EEWDLVLAAS AASTEVSILA RQSDQINWES WLLEDSSRAE LPVTDKSDDS
370 380 390 400 410 420
LPMGVVVDYT NQVEITISDE KTLPPAPVLM LLSTDGVLCP FYMINQNPGV KSLIKTPERL
430 440 450 460 470 480
SLEGERQPKS PGSTPTTPTS SQAPQKLDAS AAAAPASLPP SSPAAPIATF SLLPAGGAPT
490 500 510 520 530 540
VFSFGSSSLK SSATVTGEPP SYSSGSDSSK AAPGPGPSTF SFVPPSKASL APTPAASPVA
550 560 570 580 590 600
PSAASFSFGS SGFKPTLEST PVPSVSAPNI AMKPSFPPST SAVKVNLSEK FTAAATSTPV
610 620 630 640 650 660
SSSQSAPPMS PFSSASKPAA SGPLSHPTPL SAPPSSVPLK SSVLPSPSGR SAQGSSSPVP
670 680 690 700 710 720
SMVQKSPRIT PPAAKPGSPQ AKSLQPAVAE KQGHQWKDSD PVMAGIGEEI AHFQKELEEL
730 740 750 760 770 780
KARTSKACFQ VGTSEEMKML RTESDDLHTF LLEIKETTES LHGDISSLKT TLLEGFAGVE
790 800 810 820 830 840
EAREQNERNR DSGYLHLLYK RPLDPKSEAQ LQEIRRLHQY VKFAVQDVND VLDLEWDQHL
850 860 870 880 890 900
EQKKKQRHLL VPERETLFNT LANNREIINQ QRKRLNHLVD SLQQLRLYKQ TSLWSLSSAV
910 920 930 940 950 960
PSQSSIHSFD SDLESLCNAL LKTTIESHTK SLPKVPAKLS PMKQAQLRNF LAKRKTPPVR
970 980 990 1000 1010 1020
STAPASLSRS AFLSQRYYED LDEVSSTSSV SQSLESEDAR TSCKDDEAVV QAPRHAPVVR
1030 1040 1050 1060 1070 1080
TPSIQPSLLP HAAPFAKSHL VHGSSPGVMG TSVATSASKI IPQGADSTML ATKTVKHGAP
1090 1100 1110 1120 1130 1140
SPSHPISAPQ AAAAAALRRQ MASQAPAVNT LTESTLKNVP QVVNVQELKN NPATPSTAMG
1150 1160 1170 1180 1190 1200
SSVPYSTAKT PHPVLTPVAA NQAKQGSLIN SLKPSGPTPA SGQLSSGDKA SGTAKIETAV
1210 1220 1230 1240 1250 1260
TSTPSASGQF SKPFSFSPSG TGFNFGIITP TPSSNFTAAQ GATPSTKESS QPDAFSSGGG
1270 1280 1290 1300 1310 1320
SKPSYEAIPE SSPPSGITSA SNTTPGEPAA SSSRPVAPSG TALSTTSSKL ETPPSKLGEL
1330 1340 1350 1360 1370 1380
LFPSSLAGET LGSFSGLRVG QADDSTKPTN KASSTSLTST QPTKTSGVPS GFNFTAPPVL
1390 1400 1410 1420 1430 1440
GKHTEPPVTS SATTTSVAPP AATSTSSTAV FGSLPVTSAG SSGVISFGGT SLSAGKTSFS
1450 1460 1470 1480 1490 1500
FGSQQTNSTV PPSAPPPTTA ATPLPTSFPT LSFGSLLSSA TTPSLPMSAG RSTEEATSSA
1510 1520 1530 1540 1550 1560
LPEKPGDSEV SASAASLLEE QQSAQLPQAP PQTSDSVKKE PVLAQPAVSN SGTAASSTSL
1570 1580 1590 1600 1610 1620
VALSAEATPA TTGVPDARTE AVPPASSFSV PGQTAVTAAA ISSAGPVAVE TSSTPIASST
1630 1640 1650 1660 1670 1680
TSIVAPGPSA EAAAFGTVTS GSSVFAQPPA ASSSSAFNQL TNNTATAPSA TPVFGQVAAS
1690 1700 1710 1720 1730 1740
TAPSLFGQQT GSTASTAAAT PQVSSSGFSS PAFGTTAPGV FGQTTFGQAS VFGQSASSAA
1750 1760 1770 1780 1790 1800
SVFSFSQPGF SSVPAFGQPA SSTPTSTSGS VFGAASSTSS SSSFSFGQSS PNTGGGLFGQ
1810 1820 1830 1840 1850 1860
SNAPAFGQSP GFGQGGSVFG GTSAATTTAA TSGFSFCQAS GFGSSNTGSV FGQAASTGGI
1870 1880 1890 1900 1910 1920
VFGQQSSSSS GSVFGSGNTG RGGGFFSGLG GKPSQDAANK NPFSSASGGF GSTATSNTSN
1930 1940 1950 1960 1970 1980
LFGNSGAKTF GGFASSSFGE QKPTGTFSSG GGSVASQGFG FSSPNKTGGF GAAPVFGSPP
1990 2000 2010 2020 2030 2040
TFGGSPGFGG VPAFGSAPAF TSPLGSTGGK VFGEGTAAAS AGGFGFGSSS NTTSFGTLAS
2050 2060 2070 2080 2090
QNAPTFGSLS QQTSGFGTQS SGFSGFGSGT GGFSFGSNNS SVQGFGGWRS
10 20 30 40 50 60
MGDEMDAMIP EREMKDFQFR ALKKVRIFDS PEELPKERSS LLAVSNKYGL VFAGGASGLQ
70 80 90 100 110 120
IFPTKNLLIQ NKPGDDPNKI VDKVQGLLVP MKFPIHHLAL SCDNLTLSAC MMSSEYGSII
130 140 150 160 170 180
AFFDVRTFSN EAKQQKRPFA YHKLLKDAGG MVIDMKWNPT VPSMVAVCLA DGSIAVLQVT
190 200 210 220 230 240
ETVKVCATLP STVAVTSVCW SPKGKQLAVG KQNGTVVQYL PTLQEKKVIP CPPFYESDHP
250 260 270 280 290 300
VRVLDVLWIG TYVFAIVYAA ADGTLETSPD VVMALLPKKE EKHPEIFVNF MEPCYGSCTE
310 320 330 340 350 360
RQHHYYLSYI EEWDLVLAAS AASTEVSILA RQSDQINWES WLLEDSSRAE LPVTDKSDDS
370 380 390 400 410 420
LPMGVVVDYT NQVEITISDE KTLPPAPVLM LLSTDGVLCP FYMINQNPGV KSLIKTPERL
430 440 450 460 470 480
SLEGERQPKS PGSTPTTPTS SQAPQKLDAS AAAAPASLPP SSPAAPIATF SLLPAGGAPT
490 500 510 520 530 540
VFSFGSSSLK SSATVTGEPP SYSSGSDSSK AAPGPGPSTF SFVPPSKASL APTPAASPVA
550 560 570 580 590 600
PSAASFSFGS SGFKPTLEST PVPSVSAPNI AMKPSFPPST SAVKVNLSEK FTAAATSTPV
610 620 630 640 650 660
SSSQSAPPMS PFSSASKPAA SGPLSHPTPL SAPPSSVPLK SSVLPSPSGR SAQGSSSPVP
670 680 690 700 710 720
SMVQKSPRIT PPAAKPGSPQ AKSLQPAVAE KQGHQWKDSD PVMAGIGEEI AHFQKELEEL
730 740 750 760 770 780
KARTSKACFQ VGTSEEMKML RTESDDLHTF LLEIKETTES LHGDISSLKT TLLEGFAGVE
790 800 810 820 830 840
EAREQNERNR DSGYLHLLYK RPLDPKSEAQ LQEIRRLHQY VKFAVQDVND VLDLEWDQHL
850 860 870 880 890 900
EQKKKQRHLL VPERETLFNT LANNREIINQ QRKRLNHLVD SLQQLRLYKQ TSLWSLSSAV
910 920 930 940 950 960
PSQSSIHSFD SDLESLCNAL LKTTIESHTK SLPKVPAKLS PMKQAQLRNF LAKRKTPPVR
970 980 990 1000 1010 1020
STAPASLSRS AFLSQRYYED LDEVSSTSSV SQSLESEDAR TSCKDDEAVV QAPRHAPVVR
1030 1040 1050 1060 1070 1080
TPSIQPSLLP HAAPFAKSHL VHGSSPGVMG TSVATSASKI IPQGADSTML ATKTVKHGAP
1090 1100 1110 1120 1130 1140
SPSHPISAPQ AAAAAALRRQ MASQAPAVNT LTESTLKNVP QVVNVQELKN NPATPSTAMG
1150 1160 1170 1180 1190 1200
SSVPYSTAKT PHPVLTPVAA NQAKQGSLIN SLKPSGPTPA SGQLSSGDKA SGTAKIETAV
1210 1220 1230 1240 1250 1260
TSTPSASGQF SKPFSFSPSG TGFNFGIITP TPSSNFTAAQ GATPSTKESS QPDAFSSGGG
1270 1280 1290 1300 1310 1320
SKPSYEAIPE SSPPSGITSA SNTTPGEPAA SSSRPVAPSG TALSTTSSKL ETPPSKLGEL
1330 1340 1350 1360 1370 1380
LFPSSLAGET LGSFSGLRVG QADDSTKPTN KASSTSLTST QPTKTSGVPS GFNFTAPPVL
1390 1400 1410 1420 1430 1440
GKHTEPPVTS SATTTSVAPP AATSTSSTAV FGSLPVTSAG SSGVISFGGT SLSAGKTSFS
1450 1460 1470 1480 1490 1500
FGSQQTNSTV PPSAPPPTTA ATPLPTSFPT LSFGSLLSSA TTPSLPMSAG RSTEEATSSA
1510 1520 1530 1540 1550 1560
LPEKPGDSEV SASAASLLEE QQSAQLPQAP PQTSDSVKKE PVLAQPAVSN SGTAASSTSL
1570 1580 1590 1600 1610 1620
VALSAEATPA TTGVPDARTE AVPPASSFSV PGQTAVTAAA ISSAGPVAVE TSSTPIASST
1630 1640 1650 1660 1670 1680
TSIVAPGPSA EAAAFGTVTS GSSVFAQPPA ASSSSAFNQL TNNTATAPSA TPVFGQVAAS
1690 1700 1710 1720 1730 1740
TAPSLFGQQT GSTASTAAAT PQVSSSGFSS PAFGTTAPGV FGQTTFGQAS VFGQSASSAA
1750 1760 1770 1780 1790 1800
SVFSFSQPGF SSVPAFGQPA SSTPTSTSGS VFGAASSTSS SSSFSFGQSS PNTGGGLFGQ
1810 1820 1830 1840 1850 1860
SNAPAFGQSP GFGQGGSVFG GTSAATTTAA TSGFSFCQAS GFGSSNTGSV FGQAASTGGI
1870 1880 1890 1900 1910 1920
VFGQQSSSSS GSVFGSGNTG RGGGFFSGLG GKPSQDAANK NPFSSASGGF GSTATSNTSN
1930 1940 1950 1960 1970 1980
LFGNSGAKTF GGFASSSFGE QKPTGTFSSG GGSVASQGFG FSSPNKTGGF GAAPVFGSPP
1990 2000 2010 2020 2030 2040
TFGGSPGFGG VPAFGSAPAF TSPLGSTGGK VFGEGTAAAS AGGFGFGSSS NTTSFGTLAS
2050 2060 2070 2080 2090
QNAPTFGSLS QQTSGFGTQS SGFSGFGSGT GGFSFGSNNS SVQGFGGWRS
10 20 30 40 50 60
MGDEMDAMIP EREMKDFQFR ALKKVRIFDS PEELPKERSS LLAVSNKYGL VFAGGASGLQ
70 80 90 100 110 120
IFPTKNLLIQ NKPGDDPNKI VDKVQGLLVP MKFPIHHLAL SCDNLTLSAC MMSSEYGSII
130 140 150 160 170 180
AFFDVRTFSN EAKQQKRPFA YHKLLKDAGG MVIDMKWNPT VPSMVAVCLA DGSIAVLQVT
190 200 210 220 230 240
ETVKVCATLP STVAVTSVCW SPKGKQLAVG KQNGTVVQYL PTLQEKKVIP CPPFYESDHP
250 260 270 280 290 300
VRVLDVLWIG TYVFAIVYAA ADGTLETSPD VVMALLPKKE EKHPEIFVNF MEPCYGSCTE
310 320 330 340 350 360
RQHHYYLSYI EEWDLVLAAS AASTEVSILA RQSDQINWES WLLEDSSRAE LPVTDKSDDS
370 380 390 400 410 420
LPMGVVVDYT NQVEITISDE KTLPPAPVLM LLSTDGVLCP FYMINQNPGV KSLIKTPERL
430 440 450 460 470 480
SLEGERQPKS PGSTPTTPTS SQAPQKLDAS AAAAPASLPP SSPAAPIATF SLLPAGGAPT
490 500 510 520 530 540
VFSFGSSSLK SSATVTGEPP SYSSGSDSSK AAPGPGPSTF SFVPPSKASL APTPAASPVA
550 560 570 580 590 600
PSAASFSFGS SGFKPTLEST PVPSVSAPNI AMKPSFPPST SAVKVNLSEK FTAAATSTPV
610 620 630 640 650 660
SSSQSAPPMS PFSSASKPAA SGPLSHPTPL SAPPSSVPLK SSVLPSPSGR SAQGSSSPVP
670 680 690 700 710 720
SMVQKSPRIT PPAAKPGSPQ AKSLQPAVAE KQGHQWKDSD PVMAGIGEEI AHFQKELEEL
730 740 750 760 770 780
KARTSKACFQ VGTSEEMKML RTESDDLHTF LLEIKETTES LHGDISSLKT TLLEGFAGVE
790 800 810 820 830 840
EAREQNERNR DSGYLHLLYK RPLDPKSEAQ LQEIRRLHQY VKFAVQDVND VLDLEWDQHL
850 860 870 880 890 900
EQKKKQRHLL VPERETLFNT LANNREIINQ QRKRLNHLVD SLQQLRLYKQ TSLWSLSSAV
910 920 930 940 950 960
PSQSSIHSFD SDLESLCNAL LKTTIESHTK SLPKVPAKLS PMKQAQLRNF LAKRKTPPVR
970 980 990 1000 1010 1020
STAPASLSRS AFLSQRYYED LDEVSSTSSV SQSLESEDAR TSCKDDEAVV QAPRHAPVVR
1030 1040 1050 1060 1070 1080
TPSIQPSLLP HAAPFAKSHL VHGSSPGVMG TSVATSASKI IPQGADSTML ATKTVKHGAP
1090 1100 1110 1120 1130 1140
SPSHPISAPQ AAAAAALRRQ MASQAPAVNT LTESTLKNVP QVVNVQELKN NPATPSTAMG
1150 1160 1170 1180 1190 1200
SSVPYSTAKT PHPVLTPVAA NQAKQGSLIN SLKPSGPTPA SGQLSSGDKA SGTAKIETAV
1210 1220 1230 1240 1250 1260
TSTPSASGQF SKPFSFSPSG TGFNFGIITP TPSSNFTAAQ GATPSTKESS QPDAFSSGGG
1270 1280 1290 1300 1310 1320
SKPSYEAIPE SSPPSGITSA SNTTPGEPAA SSSRPVAPSG TALSTTSSKL ETPPSKLGEL
1330 1340 1350 1360 1370 1380
LFPSSLAGET LGSFSGLRVG QADDSTKPTN KASSTSLTST QPTKTSGVPS GFNFTAPPVL
1390 1400 1410 1420 1430 1440
GKHTEPPVTS SATTTSVAPP AATSTSSTAV FGSLPVTSAG SSGVISFGGT SLSAGKTSFS
1450 1460 1470 1480 1490 1500
FGSQQTNSTV PPSAPPPTTA ATPLPTSFPT LSFGSLLSSA TTPSLPMSAG RSTEEATSSA
1510 1520 1530 1540 1550 1560
LPEKPGDSEV SASAASLLEE QQSAQLPQAP PQTSDSVKKE PVLAQPAVSN SGTAASSTSL
1570 1580 1590 1600 1610 1620
VALSAEATPA TTGVPDARTE AVPPASSFSV PGQTAVTAAA ISSAGPVAVE TSSTPIASST
1630 1640 1650 1660 1670 1680
TSIVAPGPSA EAAAFGTVTS GSSVFAQPPA ASSSSAFNQL TNNTATAPSA TPVFGQVAAS
1690 1700 1710 1720 1730 1740
TAPSLFGQQT GSTASTAAAT PQVSSSGFSS PAFGTTAPGV FGQTTFGQAS VFGQSASSAA
1750 1760 1770 1780 1790 1800
SVFSFSQPGF SSVPAFGQPA SSTPTSTSGS VFGAASSTSS SSSFSFGQSS PNTGGGLFGQ
1810 1820 1830 1840 1850 1860
SNAPAFGQSP GFGQGGSVFG GTSAATTTAA TSGFSFCQAS GFGSSNTGSV FGQAASTGGI
1870 1880 1890 1900 1910 1920
VFGQQSSSSS GSVFGSGNTG RGGGFFSGLG GKPSQDAANK NPFSSASGGF GSTATSNTSN
1930 1940 1950 1960 1970 1980
LFGNSGAKTF GGFASSSFGE QKPTGTFSSG GGSVASQGFG FSSPNKTGGF GAAPVFGSPP
1990 2000 2010 2020 2030 2040
TFGGSPGFGG VPAFGSAPAF TSPLGSTGGK VFGEGTAAAS AGGFGFGSSS NTTSFGTLAS
2050 2060 2070 2080 2090
QNAPTFGSLS QQTSGFGTQS SGFSGFGSGT GGFSFGSNNS SVQGFGGWRS
10 20 30 40 50 60
MGDEMDAMIP EREMKDFQFR ALKKVRIFDS PEELPKERSS LLAVSNKYGL VFAGGASGLQ
70 80 90 100 110 120
IFPTKNLLIQ NKPGDDPNKI VDKVQGLLVP MKFPIHHLAL SCDNLTLSAC MMSSEYGSII
130 140 150 160 170 180
AFFDVRTFSN EAKQQKRPFA YHKLLKDAGG MVIDMKWNPT VPSMVAVCLA DGSIAVLQVT
190 200 210 220 230 240
ETVKVCATLP STVAVTSVCW SPKGKQLAVG KQNGTVVQYL PTLQEKKVIP CPPFYESDHP
250 260 270 280 290 300
VRVLDVLWIG TYVFAIVYAA ADGTLETSPD VVMALLPKKE EKHPEIFVNF MEPCYGSCTE
310 320 330 340 350 360
RQHHYYLSYI EEWDLVLAAS AASTEVSILA RQSDQINWES WLLEDSSRAE LPVTDKSDDS
370 380 390 400 410 420
LPMGVVVDYT NQVEITISDE KTLPPAPVLM LLSTDGVLCP FYMINQNPGV KSLIKTPERL
430 440 450 460 470 480
SLEGERQPKS PGSTPTTPTS SQAPQKLDAS AAAAPASLPP SSPAAPIATF SLLPAGGAPT
490 500 510 520 530 540
VFSFGSSSLK SSATVTGEPP SYSSGSDSSK AAPGPGPSTF SFVPPSKASL APTPAASPVA
550 560 570 580 590 600
PSAASFSFGS SGFKPTLEST PVPSVSAPNI AMKPSFPPST SAVKVNLSEK FTAAATSTPV
610 620 630 640 650 660
SSSQSAPPMS PFSSASKPAA SGPLSHPTPL SAPPSSVPLK SSVLPSPSGR SAQGSSSPVP
670 680 690 700 710 720
SMVQKSPRIT PPAAKPGSPQ AKSLQPAVAE KQGHQWKDSD PVMAGIGEEI AHFQKELEEL
730 740 750 760 770 780
KARTSKACFQ VGTSEEMKML RTESDDLHTF LLEIKETTES LHGDISSLKT TLLEGFAGVE
790 800 810 820 830 840
EAREQNERNR DSGYLHLLYK RPLDPKSEAQ LQEIRRLHQY VKFAVQDVND VLDLEWDQHL
850 860 870 880 890 900
EQKKKQRHLL VPERETLFNT LANNREIINQ QRKRLNHLVD SLQQLRLYKQ TSLWSLSSAV
910 920 930 940 950 960
PSQSSIHSFD SDLESLCNAL LKTTIESHTK SLPKVPAKLS PMKQAQLRNF LAKRKTPPVR
970 980 990 1000 1010 1020
STAPASLSRS AFLSQRYYED LDEVSSTSSV SQSLESEDAR TSCKDDEAVV QAPRHAPVVR
1030 1040 1050 1060 1070 1080
TPSIQPSLLP HAAPFAKSHL VHGSSPGVMG TSVATSASKI IPQGADSTML ATKTVKHGAP
1090 1100 1110 1120 1130 1140
SPSHPISAPQ AAAAAALRRQ MASQAPAVNT LTESTLKNVP QVVNVQELKN NPATPSTAMG
1150 1160 1170 1180 1190 1200
SSVPYSTAKT PHPVLTPVAA NQAKQGSLIN SLKPSGPTPA SGQLSSGDKA SGTAKIETAV
1210 1220 1230 1240 1250 1260
TSTPSASGQF SKPFSFSPSG TGFNFGIITP TPSSNFTAAQ GATPSTKESS QPDAFSSGGG
1270 1280 1290 1300 1310 1320
SKPSYEAIPE SSPPSGITSA SNTTPGEPAA SSSRPVAPSG TALSTTSSKL ETPPSKLGEL
1330 1340 1350 1360 1370 1380
LFPSSLAGET LGSFSGLRVG QADDSTKPTN KASSTSLTST QPTKTSGVPS GFNFTAPPVL
1390 1400 1410 1420 1430 1440
GKHTEPPVTS SATTTSVAPP AATSTSSTAV FGSLPVTSAG SSGVISFGGT SLSAGKTSFS
1450 1460 1470 1480 1490 1500
FGSQQTNSTV PPSAPPPTTA ATPLPTSFPT LSFGSLLSSA TTPSLPMSAG RSTEEATSSA
1510 1520 1530 1540 1550 1560
LPEKPGDSEV SASAASLLEE QQSAQLPQAP PQTSDSVKKE PVLAQPAVSN SGTAASSTSL
1570 1580 1590 1600 1610 1620
VALSAEATPA TTGVPDARTE AVPPASSFSV PGQTAVTAAA ISSAGPVAVE TSSTPIASST
1630 1640 1650 1660 1670 1680
TSIVAPGPSA EAAAFGTVTS GSSVFAQPPA ASSSSAFNQL TNNTATAPSA TPVFGQVAAS
1690 1700 1710 1720 1730 1740
TAPSLFGQQT GSTASTAAAT PQVSSSGFSS PAFGTTAPGV FGQTTFGQAS VFGQSASSAA
1750 1760 1770 1780 1790 1800
SVFSFSQPGF SSVPAFGQPA SSTPTSTSGS VFGAASSTSS SSSFSFGQSS PNTGGGLFGQ
1810 1820 1830 1840 1850 1860
SNAPAFGQSP GFGQGGSVFG GTSAATTTAA TSGFSFCQAS GFGSSNTGSV FGQAASTGGI
1870 1880 1890 1900 1910 1920
VFGQQSSSSS GSVFGSGNTG RGGGFFSGLG GKPSQDAANK NPFSSASGGF GSTATSNTSN
1930 1940 1950 1960 1970 1980
LFGNSGAKTF GGFASSSFGE QKPTGTFSSG GGSVASQGFG FSSPNKTGGF GAAPVFGSPP
1990 2000 2010 2020 2030 2040
TFGGSPGFGG VPAFGSAPAF TSPLGSTGGK VFGEGTAAAS AGGFGFGSSS NTTSFGTLAS
2050 2060 2070 2080 2090
QNAPTFGSLS QQTSGFGTQS SGFSGFGSGT GGFSFGSNNS SVQGFGGWRS
Protein Neighborhood
Domains & Features
15 N-termini - 3 C-termini - 2 Cleavages - 0 Substrates
N-termini
Name | Sequence | Position | Modification | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMID) |
---|---|---|---|---|---|---|---|---|---|
P35658-1-unknown | MGDEMD... | 1 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt83483 | |||
P35658-1-unknown | MGDEMD... | 1 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt83484 | |||
P35658-1-unknown | MGDEMD... | 1 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt83485 | |||
P35658-1-unknown | MGDEMD... | 1 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt83486 | |||
P35658-2-unknown | MGDEMD... | 1 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
P35658-1-acetylation | MGDEMD... | 1 | acetylation- | COFRADIC | Gevaert K. | Van Damme P et al.: Complementary positional proteomics for screening substrates... | 20526345 | ||
P35658-1-acetylation | MGDEMD... | 1 | acetylation- | COFRADIC | Gevaert K. | Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates... | 20526345 | ||
P35658-1-acetylation | MGDEMD... | 1 | acetylation- | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt162776 | ||
P35658-1-acetylation | MGDEMD... | 1 | acetylation- | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt162777 | ||
P35658-1-acetylation | MGDEMD... | 1 | acetylation- | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt162778 | ||
P35658-1-acetylation | MGDEMD... | 1 | acetylation- | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt162779 | ||
P35658-2-Acetylation | GDEMDA... | 2 | acetylation- | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | ||
P35658-2-Acetylation | GDEMDA... | 2 | acetylation- | COFRADIC | Gevaert K. | Van Damme P et al.: Complementary positional proteomics for screening substrates... | 20526345 | ||
P35658-2-Acetylation | GDEMDA... | 2 | acetylation- | other | CNRS/ISV | Large_scale_NTA_Human | |||
P35658-2-Acetylation | GDEMDA... | 2 | acetylation- | COFRADIC | Gevaert K. | Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates... | 20526345 | ||
P35658-2-Acetylation | GDEMDA... | 2 | acetylation- | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt111290 | ||
P35658-2-Acetylation | GDEMDA... | 2 | acetylation- | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt111291 | ||
P35658-2-Acetylation | GDEMDA... | 2 | acetylation- | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt111292 | ||
P35658-2-Acetylation | GDEMDA... | 2 | acetylation- | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt111293 | ||
P35658-7- | AMIPER... | 7 | Subtiligase Based Positive Selection | Wells | apoptotic_MM1s_bort | 23264352 | |||
P35658-7-unknown | AMIPER... | 7 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt174536 | |||
P35658-7-unknown | AMIPER... | 7 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt174537 | |||
P35658-7-unknown | AMIPER... | 7 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt174538 | |||
P35658-7-unknown | AMIPER... | 7 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt174539 | |||
P35658-988-unknown | SSVSQS... | 988 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC11464 | |||
P35658-988-unknown | SSVSQS... | 988 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt157096 | |||
P35658-988-unknown | SSVSQS... | 988 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt157097 | |||
P35658-988-unknown | SSVSQS... | 988 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt157100 | |||
P35658-988-unknown | SSVSQS... | 988 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt157131 | |||
P35658-1023-unknown | SIQPSL... | 1023 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt175542 | |||
P35658-1023-unknown | SIQPSL... | 1023 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt175545 | |||
P35658-1023-unknown | SIQPSL... | 1023 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt175543 | |||
P35658-1023-unknown | SIQPSL... | 1023 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt175544 | |||
P35658-1023- | SIQPSL... | 1023 | Subtiligase Based Positive Selection | Wells | apoptotic_MM1s_bort | 23264352 | |||
P35658-1171-unknown | SLKPSG... | 1171 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt175547 | |||
P35658-1171-unknown | SLKPSG... | 1171 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt175550 | |||
P35658-1171-unknown | SLKPSG... | 1171 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt175548 | |||
P35658-1171-unknown | SLKPSG... | 1171 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt175549 | |||
P35658-1171- | SLKPSG... | 1171 | Subtiligase Based Positive Selection | Wells | apoptotic_MM1s_bort | 23264352 | |||
P35658-1479-unknown | SATTPS... | 1479 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt168445 | |||
P35658-1479-unknown | SATTPS... | 1479 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt168448 | |||
P35658-1479-unknown | SATTPS... | 1479 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt168446 | |||
P35658-1479-unknown | SATTPS... | 1479 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt168447 | |||
P35658-1479- | SATTPS... | 1479 | Subtiligase Based Positive Selection | Wells | apoptotic_Jurkat_bortezomib | 23264352 | |||
P35658-1479- | SATTPS... | 1479 | Subtiligase Based Positive Selection | Wells | apoptosis_U266_bortezomib_induced | 23264352 | |||
P35658-1564-unknown | SAEATP... | 1564 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC14095 | |||
P35658-1564-unknown | SAEATP... | 1564 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt158231 | |||
P35658-1564-unknown | SAEATP... | 1564 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt158258 | |||
P35658-1564-unknown | SAEATP... | 1564 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt158265 | |||
P35658-1564-unknown | SAEATP... | 1564 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt158280 | |||
P35658-1564- | SAEATP... | 1564 | Subtiligase Based Positive Selection | Wells | apoptotic_Jurkat_staurotrail | 23264352 |
C-termini
Name | Sequence | Position | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
---|---|---|---|---|---|---|---|---|
...EVSSTS | 987 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC11464 | |||
...EVSSTS | 987 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt140595 | |||
...EVSSTS | 987 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt140596 | |||
...EVSSTS | 987 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt140600 | |||
...EVSSTS | 987 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt140631 | |||
...SLVALS | 1563 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC14095 | |||
...SLVALS | 1563 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt141727 | |||
...SLVALS | 1563 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt141754 | |||
...SLVALS | 1563 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt141761 | |||
...SLVALS | 1563 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt141776 | |||
...GGWRS | 2090 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
...GGWRS | 2090 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt79101 | |||
...GGWRS | 2090 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt79103 | |||
...GGWRS | 2090 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt79102 |
Cleavages
Protease | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
---|---|---|---|---|---|---|---|---|
GRAB_HUMAN | 987 | SSTS.|.SSVS | inferred from experiment | unknown | MEROPS | Gevaert K | Van Damme P et al.:Complementary positional proteo... (M14.017) | 20526345, |
GRAM_HUMAN | 1563 | VALS.|.SAEA | inferred from experiment | unknown | MEROPS | Bovenschen N | de Poot SA et al.:Human and mouse granzyme M disp... (S01.139) | 21564021, |
Substrates
Substrate | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
---|