P29084: Transcription initiation factor IIE subunit beta

General Information

Protein names	- Transcription initiation factor IIE subunit beta - TFIIE-beta - General transcription factor IIE subunit 2
Gene names	GTF2E2
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	P29084

4 N-termini

4 C-termini

1 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MDPSLLRERE LFKKRALSTP VVEKRSASSE SSSSSSKKKK TKVEHGGSSG SKQNSDHSNG
        70         80         90        100        110        120
SFNLKALSGS SGYKFGVLAK IVNYMKTRHQ RGDTHPLTLD EILDETQHLD IGLKQKQWLM
       130        140        150        160        170        180
TEALVNNPKI EVIDGKYAFK PKYNVRDKKA LLRLLDQHDQ RGLGGILLED IEEALPNSQK
       190        200        210        220        230        240
AVKALGDQIL FVNRPDKKKI LFFNDKSCQF SVDEEFQKLW RSVTVDSMDE EKIEEYLKRQ
       250        260        270        280        290
GISSMQESGP KKVAPIQRRK KPASQKKRRF KTHNEHLAGV LKDYSDITSS K

Isoforms

Sequence View

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Evidence Names:

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Protein Neighborhood

Domains & Features

4 N-termini - 4 C-termini - 1 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
P29084-1-Acetylation	MDPSLL...	1	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P29084-1-Acetylation	MDPSLL...	1	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345
P29084-16-unknown	ALSTPV...	16			unknown			Mahrus S. et al.: nonapototic Jurkat cells, Global Sequencing of Proteolytic Cleavage...	18722006
P29084-16-	ALSTPV...	16			Subtiligase Based Positive Selection		Wells	Jurkat_untreated	23264352
P29084-16-	ALSTPV...	16			Subtiligase Based Positive Selection		Wells	apoptosis_U266_bortezomib_induced	23264352
P29084-227-unknown	SMDEEK...	227		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC11413

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...EALVNN	126	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000429312
...RPDKKK	198	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000429921
...SVTVDS	226	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC11413
...ITSSK	291	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
GRAB_HUMAN	226	TVDS.\|.SMDE	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:Complementary positional proteo... (M14.017)	20526345,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)