Q08378: Golgin subfamily A member 3

General Information

Protein names	- Golgin subfamily A member 3 - Golgi complex-associated protein of 170 kDa - GCP170 - Golgin-160
Gene names	GOLGA3
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q08378

6 N-termini

6 C-termini

6 Cleavages

0 Substrates

Sequence

Isoforms

- Isoform 2 of Golgin subfamily A member 3 - Isoform 3 of Golgin subfamily A member 3

Sequence View

        10         20         30         40         50         60
MDGASAEQDG LQEDRSHSGP SSLPEAPLKP PGPLVPPDQQ DKVQCAEVNR ASTEGESPDG
        70         80         90        100        110        120
PGQGGLCQNG PTPPFPDPPS SLDPTTSPVG PDASPGVAGF HDNLRKSQGT SAEGSVRKEA
       130        140        150        160        170        180
LQSLRLSLPM QETQLCSTDS PLPLEKEEQV RLQARKWLEE QLKQYRVKRQ QERSSQPATK
       190        200        210        220        230        240
TRLFSTLDPE LMLNPENLPR ASTLAMTKEY SFLRTSVPRG PKVGSLGLPA HPREKKTSKS
       250        260        270        280        290        300
SKIRSLADYR TEDSNAGNSG GNVPAPDSTK GSLKQNRSSA ASVVSEISLS PDTDDRLENT
       310        320        330        340        350        360
SLAGDSVSEV DGNDSDSSSY SSASTRGTYG ILSKTVGTQD TPYMVNGQEI PADTLGQFPS
       370        380        390        400        410        420
IKDVLQAAAA EHQDQGQEVN GEVRSRRDSI CSSVSLESSA AETQEEMLQV LKEKMRLEGQ
       430        440        450        460        470        480
LEALSLEASQ ALKEKAELQA QLAALSTKLQ AQVECSHSSQ QRQDSLSSEV DTLKQSCWDL
       490        500        510        520        530        540
ERAMTDLQNM LEAKNASLAS SNNDLQVAEE QYQRLMAKVE DMQRSMLSKD NTVHDLRQQM
       550        560        570        580        590        600
TALQSQLQQV QLERTTLTSK LKASQAEISS LQSVRQWYQQ QLALAQEARV RLQGEMAHIQ
       610        620        630        640        650        660
VGQMTQAGLL EHLKLENVSL SQQLTETQHR SMKEKGRIAA QLQGIEADML DQEAAFMQIQ
       670        680        690        700        710        720
EAKTMVEEDL QRRLEEFEGE RERLQRMADS AASLEQQLEQ VKLTLLQRDQ QLEALQQEHL
       730        740        750        760        770        780
DLMKQLTLTQ EALQSREQSL DALQTHYDEL QARLGELQGE AASREDTICL LQNEKIILEA
       790        800        810        820        830        840
ALQAAKSGKE ELDRGARRLE EGTEETSETL EKLREELAIK SGQVEHLQQE TAALKKQMQK
       850        860        870        880        890        900
IKEQFLQQKV MVEAYRRDAT SKDQLISELK ATRKRLDSEL KELRQELMQV HGEKRTAEAE
       910        920        930        940        950        960
LSRLHREVAQ VRQHMADLEG HLQSAQKERD EMETHLQSLQ FDKEQMVAVT EANEALKKQI
       970        980        990       1000       1010       1020
EELQQEARKA ITEQKQKMRR LGSDLTSAQK EMKTKHKAYE NAVGILSRRL QEALAAKEAA
      1030       1040       1050       1060       1070       1080
DAELGQLRAQ GGSSDSSLAL HERIQALEAE LQAVSHSKTL LEKELQEVIA LTSQELEESR
      1090       1100       1110       1120       1130       1140
EKVLELEDEL QESRGFRKKI KRLEESNKKL ALELEHEKGK LTGLGQSNAA LREHNSILET
      1150       1160       1170       1180       1190       1200
ALAKREADLV QLNLQVQAVL QRKEEEDRQM KHLVQALQAS LEKEKEKVNS LKEQVAAAKV
      1210       1220       1230       1240       1250       1260
EAGHNRRHFK AASLELSEVK KELQAKEHLV QKLQAEADDL QIREGKHSQE IAQFQAELAE
      1270       1280       1290       1300       1310       1320
ARAQLQLLQK QLDEQLSKQP VGNQEMENLK WEVDQKEREI QSLKQQLDLT EQQGRKELEG
      1330       1340       1350       1360       1370       1380
LQQLLQNVKS ELEMAQEDLS MTQKDKFMLQ AKVSELKNNM KTLLQQNQQL KLDLRRGAAK
      1390       1400       1410       1420       1430       1440
TRKEPKGEAS SSNPATPIKI PDCPVPASLL EELLRPPPAV SKEPLKNLNS CLQQLKQEMD
      1450       1460       1470       1480       1490
SLQRQMEEHA LTVHESLSSW TPLEPATASP VPPGGHAGPR GDPQRHSQSR ASKEGPGE         10         20         30         40         50         60
MDGASAEQDG LQEDRSHSGP SSLPEAPLKP PGPLVPPDQQ DKVQCAEVNR ASTEGESPDG
        70         80         90        100        110        120
PGQGGLCQNG PTPPFPDPPS SLDPTTSPVG PDASPGVAGF HDNLRKSQGT SAEGSVRKEA
       130        140        150        160        170        180
LQSLRLSLPM QETQLCSTDS PLPLEKEEQV RLQARKWLEE QLKQYRVKRQ QERSSQPATK
       190        200        210        220        230        240
TRLFSTLDPE LMLNPENLPR ASTLAMTKEY SFLRTSVPRG PKVGSLGLPA HPREKKTSKS
       250        260        270        280        290        300
SKIRSLADYR TEDSNAGNSG GNVPAPDSTK GSLKQNRSSA ASVVSEISLS PDTDDRLENT
       310        320        330        340        350        360
SLAGDSVSEV DGNDSDSSSY SSASTRGTYG ILSKTVGTQD TPYMVNGQEI PADTLGQFPS
       370        380        390        400        410        420
IKDVLQAAAA EHQDQGQEVN GEVRSRRDSI CSSVSLESSA AETQEEMLQV LKEKMRLEGQ
       430        440        450        460        470        480
LEALSLEASQ ALKEKAELQA QLAALSTKLQ AQVECSHSSQ QRQDSLSSEV DTLKQSCWDL
       490        500        510        520        530        540
ERAMTDLQNM LEAKNASLAS SNNDLQVAEE QYQRLMAKVE DMQRSMLSKD NTVHDLRQQM
       550        560        570        580        590        600
TALQSQLQQV QLERTTLTSK LKASQAEISS LQSVRQWYQQ QLALAQEARV RLQGEMAHIQ
       610        620        630        640        650        660
VGQMTQAGLL EHLKLENVSL SQQLTETQHR SMKEKGRIAA QLQGIEADML DQEAAFMQIQ
       670        680        690        700        710        720
EAKTMVEEDL QRRLEEFEGE RERLQRMADS AASLEQQLEQ VKLTLLQRDQ QLEALQQEHL
       730        740        750        760        770        780
DLMKQLTLTQ EALQSREQSL DALQTHYDEL QARLGELQGE AASREDTICL LQNEKIILEA
       790        800        810        820        830        840
ALQAAKSGKE ELDRGARRLE EGTEETSETL EKLREELAIK SGQVEHLQQE TAALKKQMQK
       850        860        870        880        890        900
IKEQFLQQKV MVEAYRRDAT SKDQLISELK ATRKRLDSEL KELRQELMQV HGEKRTAEAE
       910        920        930        940        950        960
LSRLHREVAQ VRQHMADLEG HLQSAQKERD EMETHLQSLQ FDKEQMVAVT EANEALKKQI
       970        980        990       1000       1010       1020
EELQQEARKA ITEQKQKMRR LGSDLTSAQK EMKTKHKAYE NAVGILSRRL QEALAAKEAA
      1030       1040       1050       1060       1070       1080
DAELGQLRAQ GGSSDSSLAL HERIQALEAE LQAVSHSKTL LEKELQEVIA LTSQELEESR
      1090       1100       1110       1120       1130       1140
EKVLELEDEL QESRGFRKKI KRLEESNKKL ALELEHEKGK LTGLGQSNAA LREHNSILET
      1150       1160       1170       1180       1190       1200
ALAKREADLV QLNLQVQAVL QRKEEEDRQM KHLVQALQAS LEKEKEKVNS LKEQVAAAKV
      1210       1220       1230       1240       1250       1260
EAGHNRRHFK AASLELSEVK KELQAKEHLV QKLQAEADDL QIREGKHSQE IAQFQAELAE
      1270       1280       1290       1300       1310       1320
ARAQLQLLQK QLDEQLSKQP VGNQEMENLK WEVDQKEREI QSLKQQLDLT EQQGRKELEG
      1330       1340       1350       1360       1370       1380
LQQLLQNVKS ELEMAQEDLS MTQKDKFMLQ AKVSELKNNM KTLLQQNQQL KLDLRRGAAK
      1390       1400       1410       1420       1430       1440
TRKEPKGEAS SSNPATPIKI PDCPVPASLL EELLRPPPAV SKEPLKNLNS CLQQLKQEMD
      1450       1460       1470       1480       1490
SLQRQMEEHA LTVHESLSSW TPLEPATASP VPPGGHAGPR GDPQRHSQSR ASKEGPGE

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

6 N-termini - 6 C-termini - 6 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q08378-1-unknown	MDGASA...	1		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt76196
Q08378-1-unknown	MDGASA...	1		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt76197
Q08378-1-Acetylation	MDGASA...	1	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q08378-1-Acetylation	MDGASA...	1	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345
Q08378-1-Acetylation	MDGASA...	1	acetylation-		other		CNRS/ISV	Large_scale_NTA_Human
Q08378-1-Acetylation	MDGASA...	1	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345
Q08378-1-Acetylation	MDGASA...	1	acetylation-	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt99549
Q08378-1-Acetylation	MDGASA...	1	acetylation-	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt99550
Q08378-60-unknown	GPGQGG...	60		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC1366
Q08378-60-unknown	GPGQGG...	60		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt139911
Q08378-60-unknown	GPGQGG...	60		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt139913
Q08378-140-unknown	SPLPLE...	140		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC2121
Q08378-140-unknown	SPLPLE...	140		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC1369
Q08378-140-unknown	SPLPLE...	140		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt144291
Q08378-140-unknown	SPLPLE...	140		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt144292
Q08378-312-unknown	GNDSDS...	312		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC1372
Q08378-312-unknown	GNDSDS...	312		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC2950
Q08378-312-unknown	GNDSDS...	312		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt150156
Q08378-312-unknown	GNDSDS...	312		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt150157
Q08378-649-unknown	MLDQEA...	649		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC11940
Q08378-649-unknown	MLDQEA...	649		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt155302
Q08378-649-unknown	MLDQEA...	649		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt155303

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
...GESPDG	59	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC1366
...GESPDG	59	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt123016
...GESPDG	59	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt123018
...LCSTDS	139	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC2121
...LCSTDS	139	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC1369
...LCSTDS	139	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt127550
...LCSTDS	139	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt127551
...VSEVDG	311	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC1372
...VSEVDG	311	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC2950
...VSEVDG	311	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt133549
...VSEVDG	311	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt133550
...GIEADM	648	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC11940
...GIEADM	648	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt138735
...GIEADM	648	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt138736
...EGPGE	1498	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
...EGPGE	1498		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345,
...EGPGE	1498		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345,

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
CASP2_HUMAN	59	SPDG.\|.GPGQ	inferred from experiment	unknown	MEROPS	Rosen A	Mancini M et al.:Caspase-2 is localized at the G... (C14.006)	10791974,
CASP3_HUMAN	139	STDS.\|.SPLP	inferred from experiment	unknown	MEROPS	Rosen A	Mancini M et al.:Caspase-2 is localized at the G... (C14.003)	10791974,
CASP2_HUMAN	139	STDS.\|.SPLP	inferred from experiment	unknown	MEROPS	Rosen A	Mancini M et al.:Caspase-2 is localized at the G... (C14.006)	10791974,
CASP2_HUMAN	311	EVDG.\|.GNDS	inferred from experiment	unknown	MEROPS	Rosen A	Mancini M et al.:Caspase-2 is localized at the G... (C14.006)	10791974,
CASP7_HUMAN	311	EVDG.\|.GNDS	inferred from experiment	unknown	MEROPS	Rosen A	Mancini M et al.:Caspase-2 is localized at the G... (C14.003)	10791974,
GRAB_HUMAN	648	EADM.\|.MLDQ	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:Complementary positional proteo... (M14.017)	20526345,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)