Q13601: KRR1 small subunit processome component homolog

General Information

Protein names	- KRR1 small subunit processome component homolog - HIV-1 Rev-binding protein 2 - KRR-R motif-containing protein 1 - Rev-interacting protein 1 - Rip-1
Gene names	KRR1
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q13601

6 N-termini

2 C-termini

1 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MASPSLERPE KGAGKSEFRN QKPKPENQDE SELLTVPDGW KEPAFSKEDN PRGLLEESSF
        70         80         90        100        110        120
ATLFPKYREA YLKECWPLVQ KALNEHHVNA TLDLIEGSMT VCTTKKTFDP YIIIRARDLI
       130        140        150        160        170        180
KLLARSVSFE QAVRILQDDV ACDIIKIGSL VRNKERFVKR RQRLIGPKGS TLKALELLTN
       190        200        210        220        230        240
CYIMVQGNTV SAIGPFSGLK EVRKVVLDTM KNIHPIYNIK SLMIKRELAK DSELRSQSWE
       250        260        270        280        290        300
RFLPQFKHKN VNKRKEPKKK TVKKEYTPFP PPQPESQIDK ELASGEYFLK ANQKKRQKME
       310        320        330        340        350        360
AIKAKQAEAI SKRQEERNKA FIPPKEKPIV KPKEASTETK IDVASIKEKV KKAKNKKLGA
       370        380
LTAEEIALKM EADEKKKKKK K

Isoforms

- Isoform 2 of KRR1 small subunit processome component homolog

Sequence View

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

6 N-termini - 2 C-termini - 1 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q13601-2-unknown	MASPSL...	1		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q13601-1-unknown	MASPSL...	1		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt79250
Q13601-2-Acetylation	ASPSLE...	2	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q13601-2-Acetylation	ASPSLE...	2	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345
Q13601-2-Acetylation	ASPSLE...	2	acetylation-	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt111337
Q13601-39-	GWKEPA...	39			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_bortezomib	23264352
Q13601-39-	GWKEPA...	39			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_Etoposide	23264352
Q13601-39-	GWKEPA...	39			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
Q13601-39-	GWKEPA...	39			Subtiligase Based Positive Selection		Wells	apoptotic_MM1s_bort	23264352
Q13601-39-	GWKEPA...	39			Subtiligase Based Positive Selection		Wells	apoptotic_MM1SDBJurkat_Mix	23264352
Q13601-39-	GWKEPA...	39			Subtiligase Based Positive Selection		Wells	apoptotic_RPMI_Dox	23264352
Q13601-39-	GWKEPA...	39			Subtiligase Based Positive Selection		Wells	apoptosis_U266_bortezomib_induced	23264352
Q13601-39-unknown	GWKEPA...	39			unknown			Mahrus S. et al.: apototic Jurkat cells, Global Sequencing of Proteolytic Cleavage...	18722006
Q13601-39-unknown	GWKEPA...	39		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt161746
Q13601-276-unknown	SQIDKE...	276		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC12099

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...PPQPES	275	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC12099
...KKKKK	381	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...KKKKK	381	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt74868

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
GRAB_HUMAN	275	QPES.\|.SQID	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:Complementary positional proteo... (M14.017)	20526345,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)