Q5VVJ2: Histone H2A deubiquitinase MYSM1

General Information

Protein names	- Histone H2A deubiquitinase MYSM1 - 2A-DUB - 3.4.19.- - Myb-like, SWIRM and MPN domain-containing protein 1
Gene names	MYSM1
Organism	Homo sapiens
Protease Family
Protease ID	M67.005
Chromosome location
UniProt ID	Q5VVJ2

4 N-termini

2 C-termini

1 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MAAEEADVDI EGDVVAAAGA QPGSGENTAS VLQKDHYLDS SWRTENGLIP WTLDNTISEE
        70         80         90        100        110        120
NRAVIEKMLL EEEYYLSKKS QPEKVWLDQK EDDKKYMKSL QKTAKIMVHS PTKPASYSVK
       130        140        150        160        170        180
WTIEEKELFE QGLAKFGRRW TKISKLIGSR TVLQVKSYAR QYFKNKVKCG LDKETPNQKT
       190        200        210        220        230        240
GHNLQVKNED KGTKAWTPSC LRGRADPNLN AVKIEKLSDD EEVDITDEVD ELSSQTPQKN
       250        260        270        280        290        300
SSSDLLLDFP NSKMHETNQG EFITSDSQEA LFSKSSRGCL QNEKQDETLS SSEITLWTEK
       310        320        330        340        350        360
QSNGDKKSIE LNDQKFNELI KNCNKHDGRG IIVDARQLPS PEPCEIQKNL NDNEMLFHSC
       370        380        390        400        410        420
QMVEESHEEE ELKPPEQEIE IDRNIIQEEE KQAIPEFFEG RQAKTPERYL KIRNYILDQW
       430        440        450        460        470        480
EICKPKYLNK TSVRPGLKNC GDVNCIGRIH TYLELIGAIN FGCEQAVYNR PQTVDKVRIR
       490        500        510        520        530        540
DRKDAVEAYQ LAQRLQSMRT RRRRVRDPWG NWCDAKDLEG QTFEHLSAEE LAKRREEEKG
       550        560        570        580        590        600
RPVKSLKVPR PTKSSFDPFQ LIPCNFFSEE KQEPFQVKVA SEALLIMDLH AHVSMAEVIG
       610        620        630        640        650        660
LLGGRYSEVD KVVEVCAAEP CNSLSTGLQC EMDPVSQTQA SETLAVRGFS VIGWYHSHPA
       670        680        690        700        710        720
FDPNPSLRDI DTQAKYQSYF SRGGAKFIGM IVSPYNRNNP LPYSQITCLV ISEEISPDGS
       730        740        750        760        770        780
YRLPYKFEVQ QMLEEPQWGL VFEKTRWIIE KYRLSHSSVP MDKIFRRDSD LTCLQKLLEC
       790        800        810        820
MRKTLSKVTN CFMAEEFLTE IENLFLSNYK SNQENGVTEE NCTKELLM

Isoforms

- Isoform 2 of Histone H2A deubiquitinase MYSM1 - Isoform 3 of Histone H2A deubiquitinase MYSM1

Sequence View

        10         20         30         40         50         60
MAAEEADVDI EGDVVAAAGA QPGSGENTAS VLQKDHYLDS SWRTENGLIP WTLDNTISEE
        70         80         90        100        110        120
NRAVIEKMLL EEEYYLSKKS QPEKVWLDQK EDDKKYMKSL QKTAKIMVHS PTKPASYSVK
       130        140        150        160        170        180
WTIEEKELFE QGLAKFGRRW TKISKLIGSR TVLQVKSYAR QYFKNKVKCG LDKETPNQKT
       190        200        210        220        230        240
GHNLQVKNED KGTKAWTPSC LRGRADPNLN AVKIEKLSDD EEVDITDEVD ELSSQTPQKN
       250        260        270        280        290        300
SSSDLLLDFP NSKMHETNQG EFITSDSQEA LFSKSSRGCL QNEKQDETLS SSEITLWTEK
       310        320        330        340        350        360
QSNGDKKSIE LNDQKFNELI KNCNKHDGRG IIVDARQLPS PEPCEIQKNL NDNEMLFHSC
       370        380        390        400        410        420
QMVEESHEEE ELKPPEQEIE IDRNIIQEEE KQAIPEFFEG RQAKTPERYL KIRNYILDQW
       430        440        450        460        470        480
EICKPKYLNK TSVRPGLKNC GDVNCIGRIH TYLELIGAIN FGCEQAVYNR PQTVDKVRIR
       490        500        510        520        530        540
DRKDAVEAYQ LAQRLQSMRT RRRRVRDPWG NWCDAKDLEG QTFEHLSAEE LAKRREEEKG
       550        560        570        580        590        600
RPVKSLKVPR PTKSSFDPFQ LIPCNFFSEE KQEPFQVKVA SEALLIMDLH AHVSMAEVIG
       610        620        630        640        650        660
LLGGRYSEVD KVVEVCAAEP CNSLSTGLQC EMDPVSQTQA SETLAVRGFS VIGWYHSHPA
       670        680        690        700        710        720
FDPNPSLRDI DTQAKYQSYF SRGGAKFIGM IVSPYNRNNP LPYSQITCLV ISEEISPDGS
       730        740        750        760        770        780
YRLPYKFEVQ QMLEEPQWGL VFEKTRWIIE KYRLSHSSVP MDKIFRRDSD LTCLQKLLEC
       790        800        810        820
MRKTLSKVTN CFMAEEFLTE IENLFLSNYK SNQENGVTEE NCTKELLM         10         20         30         40         50         60
MAAEEADVDI EGDVVAAAGA QPGSGENTAS VLQKDHYLDS SWRTENGLIP WTLDNTISEE
        70         80         90        100        110        120
NRAVIEKMLL EEEYYLSKKS QPEKVWLDQK EDDKKYMKSL QKTAKIMVHS PTKPASYSVK
       130        140        150        160        170        180
WTIEEKELFE QGLAKFGRRW TKISKLIGSR TVLQVKSYAR QYFKNKVKCG LDKETPNQKT
       190        200        210        220        230        240
GHNLQVKNED KGTKAWTPSC LRGRADPNLN AVKIEKLSDD EEVDITDEVD ELSSQTPQKN
       250        260        270        280        290        300
SSSDLLLDFP NSKMHETNQG EFITSDSQEA LFSKSSRGCL QNEKQDETLS SSEITLWTEK
       310        320        330        340        350        360
QSNGDKKSIE LNDQKFNELI KNCNKHDGRG IIVDARQLPS PEPCEIQKNL NDNEMLFHSC
       370        380        390        400        410        420
QMVEESHEEE ELKPPEQEIE IDRNIIQEEE KQAIPEFFEG RQAKTPERYL KIRNYILDQW
       430        440        450        460        470        480
EICKPKYLNK TSVRPGLKNC GDVNCIGRIH TYLELIGAIN FGCEQAVYNR PQTVDKVRIR
       490        500        510        520        530        540
DRKDAVEAYQ LAQRLQSMRT RRRRVRDPWG NWCDAKDLEG QTFEHLSAEE LAKRREEEKG
       550        560        570        580        590        600
RPVKSLKVPR PTKSSFDPFQ LIPCNFFSEE KQEPFQVKVA SEALLIMDLH AHVSMAEVIG
       610        620        630        640        650        660
LLGGRYSEVD KVVEVCAAEP CNSLSTGLQC EMDPVSQTQA SETLAVRGFS VIGWYHSHPA
       670        680        690        700        710        720
FDPNPSLRDI DTQAKYQSYF SRGGAKFIGM IVSPYNRNNP LPYSQITCLV ISEEISPDGS
       730        740        750        760        770        780
YRLPYKFEVQ QMLEEPQWGL VFEKTRWIIE KYRLSHSSVP MDKIFRRDSD LTCLQKLLEC
       790        800        810        820
MRKTLSKVTN CFMAEEFLTE IENLFLSNYK SNQENGVTEE NCTKELLM

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
Q5VVJ2-1-unknown	MAAEEA...	1	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q5VVJ2-254-unknown	MHETNQ...	254	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt82117
Q5VVJ2-267-unknown	SQEALF...	267	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC12540
Q5VVJ2-267-unknown	SQEALF...	267	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt136527
Q5VVJ2-595-unknown	MAEVIG...	595	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt82118
Q5VVJ2-595-unknown	MAEVIG...	595	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt107001

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...FITSDS	266	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC12540
...KELLM	828	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...KELLM	828	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt77736
...KELLM	828	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt77735

TopFIND

Q5VVJ2: Histone H2A deubiquitinase MYSM1

General Information

4

N-termini

2

C-termini

1

Cleavages

0

Substrates

Sequence

Isoforms

Filter Information:

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Protein Neighborhood

Domains & Features

4 N-termini - 2 C-termini - 1 Cleavages - 0 Substrates

N-termini

C-termini

Cleavages

Substrates