Q5VTB9: E3 ubiquitin-protein ligase RNF220

General Information

Protein names	- E3 ubiquitin-protein ligase RNF220 - 2.3.2.27 - RING finger protein 220 - RING-type E3 ubiquitin transferase RNF220 {ECO:0000305}
Gene names	RNF220
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q5VTB9

3 N-termini

5 C-termini

1 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MDLHRAAFKM ENSSYLPNPL ASPALMVLAS TAEASRDASI PCQQPRPFGV PVSVDKDVHI
        70         80         90        100        110        120
PFTNGSYTFA SMYHRQGGVP GTFANRDFPP SLLHLHPQFA PPNLDCTPIS MLNHSGVGAF
       130        140        150        160        170        180
RPFASTEDRE SYQSAFTPAK RLKNCHDTES PHLRFSDADG KEYDFGTQLP SSSPGSLKVD
       190        200        210        220        230        240
DTGKKIFAVS GLISDREASS SPEDRNDRCK KKAAALFDSQ APICPICQVL LRPSELQEHM
       250        260        270        280        290        300
EQELEQLAQL PSSKNSLLKD AMAPGTPKSL LLSASIKREG ESPTASPHSS ATDDLHHSDR
       310        320        330        340        350        360
YQTFLRVRAN RQTRLNARIG KMKRRKQDEG QREGSCMAED DAVDIEHENN NRFEEYEWCG
       370        380        390        400        410        420
QKRIRATTLL EGGFRGSGFI MCSGKENPDS DADLDVDGDD TLEYGKPQYT EADVIPCTGE
       430        440        450        460        470        480
EPGEAKEREA LRGAVLNGGP PSTRITPEFS KWASDEMPST SNGESSKQEA MQKTCKNSDI
       490        500        510        520        530        540
EKITEDSAVT TFEALKARVR ELERQLSRGD RYKCLICMDS YSMPLTSIQC WHVHCEECWL
       550        560
RTLGAKKLCP QCNTITAPGD LRRIYL

Isoforms

- Isoform 2 of E3 ubiquitin-protein ligase RNF220

Sequence View

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Protein Neighborhood

Domains & Features

3 N-termini - 5 C-termini - 1 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
Q5VTB9-1-unknown	MDLHRA...	1	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q5VTB9-240-unknown	MEQELE...	240	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000414640
Q5VTB9-487-unknown	SAVTTF...	487	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC12533

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...TLLEGG	372	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000411541
...KITEDS	486	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC12533
...CLICMD	518	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000335580
...WLRTLG	543	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000388533
...RRIYL	566	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
GRAB_HUMAN	486	TEDS.\|.SAVT	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:Complementary positional proteo... (M14.017)	20526345,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)