Q6PD74: Alpha- and gamma-adaptin-binding protein p34

General Information

Protein names	- Alpha- and gamma-adaptin-binding protein p34
Gene names	AAGAB
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q6PD74

4 N-termini

4 C-termini

2 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MAAGVPCALV TSCSSVFSGD QLVQHILGTE DLIVEVTSND AVRFYPWTID NKYYSADINL
        70         80         90        100        110        120
CVVPNKFLVT AEIAESVQAF VVYFDSTQKS GLDSVSSWLP LAKAWLPEVM ILVCDRVSED
       130        140        150        160        170        180
GINRQKAQEW CIKHGFELVE LSPEELPEED DDFPESTGVK RIVQALNANV WSNVVMKNDR
       190        200        210        220        230        240
NQGFSLLNSL TGTNHSIGSA DPCHPEQPHL PAADSTESLS DHRGGASNTT DAQVDSIVDP
       250        260        270        280        290        300
MLDLDIQELA SLTTGGGDVE NFERLFSKLK EMKDKAATLP HEQRKVHAEK VAKAFWMAIG
       310
GDRDEIEGLS SDEEH

Isoforms

- Isoform 2 of Alpha- and gamma-adaptin-binding protein p34

Sequence View

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Protein Neighborhood

Domains & Features

4 N-termini - 4 C-termini - 2 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
Q6PD74-1-unknown	MAAGVP...	1	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q6PD74-110-unknown	MILVCD...	110	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt65885
Q6PD74-110-unknown	MILVCD...	110	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000453263
Q6PD74-110-unknown	MILVCD...	110	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000440735
Q6PD74-110-unknown	MILVCD...	110	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000453059
Q6PD74-236-unknown	SIVDPM...	236	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC12600
Q6PD74-236-unknown	SIVDPM...	236	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt143767
Q6PD74-276-unknown	AATLPH...	276	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC12602
Q6PD74-276-unknown	AATLPH...	276	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt145406

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...VQALNA	167	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000453059
...VQALNA	167	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt114127
...DAQVDS	235	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC12600
...DAQVDS	235	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt127009
...EMKDKA	275	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC12602
...EMKDKA	275	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt128699
...SDEEH	315	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...SDEEH	315	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt61503

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
GRAB_HUMAN	235	QVDS.\|.SIVD	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:Analysis of protein processing ... (S01.010)	18836177,
GRAB_HUMAN	275	KDKA.\|.AATL	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:Analysis of protein processing ... (S01.010)	18836177,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)