Q1MSJ5: Centrosome and spindle pole-associated protein 1
Protein names | - Centrosome and spindle pole-associated protein 1 |
---|---|
Gene names | CSPP1 |
Organism | Homo sapiens |
Protease Family | |
Protease ID | |
Chromosome location | |
UniProt ID | Q1MSJ5 |
4
N-termini
2
C-termini
1
Cleavages
0
Substrates
Sequence
10 20 30 40 50 60
MLFPLQVAAV TSSVRDDPLE HCVSPRTRAR SPEICKMADN LDEFIEEQKA RLAEDKAELE
70 80 90 100 110 120
SDPPYMEMKG KLSAKLSENS KILISMAKEN IPPNSQQTRG SLGIDYGLSL PLGEDYERKK
130 140 150 160 170 180
HKLKEELRQD YRRYLTQGIT QGKRKKNFLS TSETDPSTLG VSLPIGERLS AKERLKLERN
190 200 210 220 230 240
KEYNQFLRGK EESSEKFRQV EKSTEPKSQR NKKPIGQVKP DLTSQIQTSC ENSEGPRKDV
250 260 270 280 290 300
LTPSEAYEEL LNQRRLEEDR YRQLDDEIEL RNRRIIKKAN EEVGISNLKH QRFASKAGIP
310 320 330 340 350 360
DRRFHRFNED RVFDRRYHRP DQDPEVSEEM DERFRYESDF DRRLSRVYTN DRMHRNKRGN
370 380 390 400 410 420
MPPMEHDGDV IEQSNIRISS AENKSAPDNE TSKSANQDTC SPFAGMLFGG EDRELIQRRK
430 440 450 460 470 480
EKYRLELLEQ MAEQQRNKRR EKDLELRVAA SGAQDPEKSP DRLKQFSVAP RHFEEMIPPE
490 500 510 520 530 540
RPRIAFQTPL PPLSAPSVPP IPSVHPVPSQ NEDLRSGLSS ALGEMVSPRI APLPPPPLLP
550 560 570 580 590 600
PLATNYRTPY DDAYYFYGSR NTFDPSLAYY GSGMMGVQPA AYVSAPVTHQ LAQPVVNTVG
610 620 630 640 650 660
QNELKITSDQ VINSGLIFED KPKPSKQSLQ SYQEALQQQI REREERRKKE REEKEEYEAK
670 680 690 700 710 720
LEAEMRTYNP WGKGGGGAPL RDAKGNLITD LNRMHRQNID AYHNPDARTY EDKRAVVSLD
730 740 750 760 770 780
PNLATSNAEN LEDAANKSSG HMQTQSSPFA RGNVFGEPPT ELQIKQQELY KNFLRFQIEE
790 800 810 820 830 840
KKQREEAERE RLRIAEEKEE RRLAEQRARI QQEYEEEQEK KREKEEEQRL KNEEHIRLAE
850 860 870 880 890 900
ERQKEAERKK KEEEEKYNLQ LQHYCERDNL IGEETKHMRQ PSPIVPALQN KIASKLQRPP
910 920 930 940 950 960
SVDSIIRSFI HESSMSRAQS PPVPARKNQL RAEEEKKNVI MELSEMRKQL RSEERRLQER
970 980 990 1000 1010 1020
LLHMDSDDEI PIRKKERNPM DIFDMARHRL QAPVRRQSPK GLDAATFQNV HDFNELKDRD
1030 1040 1050 1060 1070 1080
SETRVDLKFM YLDPPRDHHT LEIQQQALLR EQQKRLNRIK MQEGAKVDLD AIPSAKVREQ
1090 1100 1110 1120 1130 1140
RMPRDDTSDF LKNSLLESDS AFIGAYGETY PAIEDDVLPP PSQLPSARER RRNKWKGLDI
1150 1160 1170 1180 1190 1200
DSSRPNVAPD GLSLKSISSV NVDELRVRNE ERMRRLNEFH NKPINTDDES SLVDPDDIMK
1210 1220 1230 1240 1250
HIGDDGSNSV ATEPWLRPGT SETLKRFMAE QLNQEQQQIP GKPGTFTWQG LSTAHG
Isoforms
- Isoform 1 of Centrosome and spindle pole-associated protein 1 - Isoform 2 of Centrosome and spindle pole-associated protein 1Sequence View
10 20 30 40 50 60
MLFPLQVAAV TSSVRDDPLE HCVSPRTRAR SPEICKMADN LDEFIEEQKA RLAEDKAELE
70 80 90 100 110 120
SDPPYMEMKG KLSAKLSENS KILISMAKEN IPPNSQQTRG SLGIDYGLSL PLGEDYERKK
130 140 150 160 170 180
HKLKEELRQD YRRYLTQGIT QGKRKKNFLS TSETDPSTLG VSLPIGERLS AKERLKLERN
190 200 210 220 230 240
KEYNQFLRGK EESSEKFRQV EKSTEPKSQR NKKPIGQVKP DLTSQIQTSC ENSEGPRKDV
250 260 270 280 290 300
LTPSEAYEEL LNQRRLEEDR YRQLDDEIEL RNRRIIKKAN EEVGISNLKH QRFASKAGIP
310 320 330 340 350 360
DRRFHRFNED RVFDRRYHRP DQDPEVSEEM DERFRYESDF DRRLSRVYTN DRMHRNKRGN
370 380 390 400 410 420
MPPMEHDGDV IEQSNIRISS AENKSAPDNE TSKSANQDTC SPFAGMLFGG EDRELIQRRK
430 440 450 460 470 480
EKYRLELLEQ MAEQQRNKRR EKDLELRVAA SGAQDPEKSP DRLKQFSVAP RHFEEMIPPE
490 500 510 520 530 540
RPRIAFQTPL PPLSAPSVPP IPSVHPVPSQ NEDLRSGLSS ALGEMVSPRI APLPPPPLLP
550 560 570 580 590 600
PLATNYRTPY DDAYYFYGSR NTFDPSLAYY GSGMMGVQPA AYVSAPVTHQ LAQPVVNTVG
610 620 630 640 650 660
QNELKITSDQ VINSGLIFED KPKPSKQSLQ SYQEALQQQI REREERRKKE REEKEEYEAK
670 680 690 700 710 720
LEAEMRTYNP WGKGGGGAPL RDAKGNLITD LNRMHRQNID AYHNPDARTY EDKRAVVSLD
730 740 750 760 770 780
PNLATSNAEN LEDAANKSSG HMQTQSSPFA RGNVFGEPPT ELQIKQQELY KNFLRFQIEE
790 800 810 820 830 840
KKQREEAERE RLRIAEEKEE RRLAEQRARI QQEYEEEQEK KREKEEEQRL KNEEHIRLAE
850 860 870 880 890 900
ERQKEAERKK KEEEEKYNLQ LQHYCERDNL IGEETKHMRQ PSPIVPALQN KIASKLQRPP
910 920 930 940 950 960
SVDSIIRSFI HESSMSRAQS PPVPARKNQL RAEEEKKNVI MELSEMRKQL RSEERRLQER
970 980 990 1000 1010 1020
LLHMDSDDEI PIRKKERNPM DIFDMARHRL QAPVRRQSPK GLDAATFQNV HDFNELKDRD
1030 1040 1050 1060 1070 1080
SETRVDLKFM YLDPPRDHHT LEIQQQALLR EQQKRLNRIK MQEGAKVDLD AIPSAKVREQ
1090 1100 1110 1120 1130 1140
RMPRDDTSDF LKNSLLESDS AFIGAYGETY PAIEDDVLPP PSQLPSARER RRNKWKGLDI
1150 1160 1170 1180 1190 1200
DSSRPNVAPD GLSLKSISSV NVDELRVRNE ERMRRLNEFH NKPINTDDES SLVDPDDIMK
1210 1220 1230 1240 1250
HIGDDGSNSV ATEPWLRPGT SETLKRFMAE QLNQEQQQIP GKPGTFTWQG LSTAHG
10 20 30 40 50 60
MLFPLQVAAV TSSVRDDPLE HCVSPRTRAR SPEICKMADN LDEFIEEQKA RLAEDKAELE
70 80 90 100 110 120
SDPPYMEMKG KLSAKLSENS KILISMAKEN IPPNSQQTRG SLGIDYGLSL PLGEDYERKK
130 140 150 160 170 180
HKLKEELRQD YRRYLTQGIT QGKRKKNFLS TSETDPSTLG VSLPIGERLS AKERLKLERN
190 200 210 220 230 240
KEYNQFLRGK EESSEKFRQV EKSTEPKSQR NKKPIGQVKP DLTSQIQTSC ENSEGPRKDV
250 260 270 280 290 300
LTPSEAYEEL LNQRRLEEDR YRQLDDEIEL RNRRIIKKAN EEVGISNLKH QRFASKAGIP
310 320 330 340 350 360
DRRFHRFNED RVFDRRYHRP DQDPEVSEEM DERFRYESDF DRRLSRVYTN DRMHRNKRGN
370 380 390 400 410 420
MPPMEHDGDV IEQSNIRISS AENKSAPDNE TSKSANQDTC SPFAGMLFGG EDRELIQRRK
430 440 450 460 470 480
EKYRLELLEQ MAEQQRNKRR EKDLELRVAA SGAQDPEKSP DRLKQFSVAP RHFEEMIPPE
490 500 510 520 530 540
RPRIAFQTPL PPLSAPSVPP IPSVHPVPSQ NEDLRSGLSS ALGEMVSPRI APLPPPPLLP
550 560 570 580 590 600
PLATNYRTPY DDAYYFYGSR NTFDPSLAYY GSGMMGVQPA AYVSAPVTHQ LAQPVVNTVG
610 620 630 640 650 660
QNELKITSDQ VINSGLIFED KPKPSKQSLQ SYQEALQQQI REREERRKKE REEKEEYEAK
670 680 690 700 710 720
LEAEMRTYNP WGKGGGGAPL RDAKGNLITD LNRMHRQNID AYHNPDARTY EDKRAVVSLD
730 740 750 760 770 780
PNLATSNAEN LEDAANKSSG HMQTQSSPFA RGNVFGEPPT ELQIKQQELY KNFLRFQIEE
790 800 810 820 830 840
KKQREEAERE RLRIAEEKEE RRLAEQRARI QQEYEEEQEK KREKEEEQRL KNEEHIRLAE
850 860 870 880 890 900
ERQKEAERKK KEEEEKYNLQ LQHYCERDNL IGEETKHMRQ PSPIVPALQN KIASKLQRPP
910 920 930 940 950 960
SVDSIIRSFI HESSMSRAQS PPVPARKNQL RAEEEKKNVI MELSEMRKQL RSEERRLQER
970 980 990 1000 1010 1020
LLHMDSDDEI PIRKKERNPM DIFDMARHRL QAPVRRQSPK GLDAATFQNV HDFNELKDRD
1030 1040 1050 1060 1070 1080
SETRVDLKFM YLDPPRDHHT LEIQQQALLR EQQKRLNRIK MQEGAKVDLD AIPSAKVREQ
1090 1100 1110 1120 1130 1140
RMPRDDTSDF LKNSLLESDS AFIGAYGETY PAIEDDVLPP PSQLPSARER RRNKWKGLDI
1150 1160 1170 1180 1190 1200
DSSRPNVAPD GLSLKSISSV NVDELRVRNE ERMRRLNEFH NKPINTDDES SLVDPDDIMK
1210 1220 1230 1240 1250
HIGDDGSNSV ATEPWLRPGT SETLKRFMAE QLNQEQQQIP GKPGTFTWQG LSTAHG
Protein Neighborhood
Domains & Features
4 N-termini - 2 C-termini - 1 Cleavages - 0 Substrates
N-termini
Name | Sequence | Position | Modification | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMID) |
---|---|---|---|---|---|---|---|---|---|
Q1MSJ5-1-unknown | MLFPLQ... | 1 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
Q1MSJ5-37-unknown | MADNLD... | 37 | inferred from electronic annotation | unknown | TISdb | inferred from TISdb | |||
Q1MSJ5-330-unknown | MDERFR... | 330 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt71933 | |||
Q1MSJ5-1100-unknown | SAFIGA... | 1100 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC12407 | |||
Q1MSJ5-1100-unknown | SAFIGA... | 1100 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt156040 |
C-termini
Name | Sequence | Position | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
---|---|---|---|---|---|---|---|---|
...LLESDS | 1099 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC12407 | |||
...LLESDS | 1099 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt139500 | |||
...STAHG | 1256 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
...STAHG | 1256 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt67551 |
Cleavages
Protease | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
---|---|---|---|---|---|---|---|---|
GRAB_HUMAN | 1099 | ESDS.|.SAFI | inferred from experiment | unknown | MEROPS | Gevaert K | Van Damme P et al.:Analysis of protein processing ... (S01.010) | 18836177, |
Substrates
Substrate | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
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