Q9H8G2: Caspase activity and apoptosis inhibitor 1

General Information

Protein names	- Caspase activity and apoptosis inhibitor 1 - Conserved anti-apoptotic protein - CAAP
Gene names	CAAP1
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q9H8G2

6 N-termini

2 C-termini

1 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MTGKKSSREK RRKRSSQEAA AALAAPDIVP ALASGSSGST SGCGSAGGCG SVSCCGNANF
        70         80         90        100        110        120
SGSVTGGGSG GSCWGGSSVE RSERRKRRST DSSSVSGSLQ QETKYILPTL EKELFLAEHS
       130        140        150        160        170        180
DLEEGGLDLT VSLKPVSFYI SDKKEMLQQC FCIIGEKKLQ KMLPDVLKNC SIEEIKKLCQ
       190        200        210        220        230        240
EQLELLSEKK ILKILEGDNG MDSDMEEEAD DGSKMGSDLV SQQDICIDSA SSVRENKQPE
       250        260        270        280        290        300
GLELKQGKGE DSDVLSINAD AYDSDIEGPC NEEAAAPEAP ENTVQSEAGQ IDDLEKDIEK
       310        320        330        340        350        360
SVNEILGLAE SSPNEPKAAT LAVPPPEDVQ PSAQQLELLE LEMRARAIKA LMKAGDIKKP

A

Isoforms

- Isoform 2 of Caspase activity and apoptosis inhibitor 1

Sequence View

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Protein Neighborhood

Domains & Features

6 N-termini - 2 C-termini - 1 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q9H8G2-1-unknown	MTGKKS...	1	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q9H8G2-146-unknown	MLQQCF...	146	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt68952
Q9H8G2-232-unknown	SVRENK...	232	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt172680
Q9H8G2-232-	SVRENK...	232		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
Q9H8G2-237-unknown	KQPEGL...	237		unknown			Mahrus S. et al.: apototic Jurkat cells, Global Sequencing of Proteolytic Cleavage...	18722006
Q9H8G2-237-unknown	KQPEGL...	237	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt161382
Q9H8G2-244-unknown	LKQGKG...	244	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC13336
Q9H8G2-244-unknown	LKQGKG...	244	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt142327

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
...PEGLEL	243	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC13336
...PEGLEL	243	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt125518
...IKKPA	361	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
...IKKPA	361	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt64570
...IKKPA	361		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345,

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
GRAB_HUMAN	243	GLEL.\|.LKQG	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:Complementary positional proteo... (M14.017)	20526345,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)