O95391: Pre-mRNA-splicing factor SLU7

General Information

Protein names	- Pre-mRNA-splicing factor SLU7 - hSlu7
Gene names	SLU7
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	O95391

6 N-termini

5 C-termini

1 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MSATVVDAVN AAPLSGSKEM SLEEPKKMTR EDWRKKKELE EQRKLGNAPA EVDEEGKDIN
        70         80         90        100        110        120
PHIPQYISSV PWYIDPSKRP TLKHQRPQPE KQKQFSSSGE WYKRGVKENS IITKYRKGAC
       130        140        150        160        170        180
ENCGAMTHKK KDCFERPRRV GAKFTGTNIA PDEHVQPQLM FDYDGKRDRW NGYNPEEHMK
       190        200        210        220        230        240
IVEEYAKVDL AKRTLKAQKL QEELASGKLV EQANSPKHQW GEEEPNSQME KDHNSEDEDE
       250        260        270        280        290        300
DKYADDIDMP GQNFDSKRRI TVRNLRIRED IAKYLRNLDP NSAYYDPKTR AMRENPYANA
       310        320        330        340        350        360
GKNPDEVSYA GDNFVRYTGD TISMAQTQLF AWEAYDKGSE VHLQADPTKL ELLYKSFKVK
       370        380        390        400        410        420
KEDFKEQQKE SILEKYGGQE HLDAPPAELL LAQTEDYVEY SRHGTVIKGQ ERAVACSKYE
       430        440        450        460        470        480
EDVKIHNHTH IWGSYWKEGR WGYKCCHSFF KYSYCTGEAG KEIVNSEECI INEITGEESV
       490        500        510        520        530        540
KKPQTLMELH QEKLKEEKKK KKKKKKKHRK SSSDSDDEEK KHEKLKKALN AEEARLLHVK
       550        560        570        580
ETMQIDERKR PYNSMYETRE PTEEEMEAYR MKRQRPDDPM ASFLGQ

Isoforms

Sequence View

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Protein Neighborhood

Domains & Features

6 N-termini - 5 C-termini - 1 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
O95391-2-unknown	MSATVV...	1		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
O95391-2-Acetylation	SATVVD...	2	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
O95391-2-Acetylation	SATVVD...	2	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345
O95391-2-Acetylation	SATVVD...	2	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345
O95391-8-unknown	AVNAAP...	8			unknown			Mahrus S. et al.: apototic Jurkat cells, Global Sequencing of Proteolytic Cleavage...	18722006
O95391-8-	AVNAAP...	8			Subtiligase Based Positive Selection		Wells	apoptotic_DB_Doxo	23264352
O95391-8-	AVNAAP...	8			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_bortezomib	23264352
O95391-8-	AVNAAP...	8			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_Etoposide	23264352
O95391-8-	AVNAAP...	8			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
O95391-8-	AVNAAP...	8			Subtiligase Based Positive Selection		Wells	apoptotic_MM1s_bort	23264352
O95391-8-	AVNAAP...	8			Subtiligase Based Positive Selection		Wells	apoptotic_MM1SDBJurkat_Mix	23264352
O95391-8-	AVNAAP...	8			Subtiligase Based Positive Selection		Wells	apoptotic_RPMI_Dox	23264352
O95391-8-	AVNAAP...	8			Subtiligase Based Positive Selection		Wells	apoptosis_U266_bortezomib_induced	23264352
O95391-153-unknown	EHVQPQ...	153		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC11022
O95391-291-	AMRENP...	291			Subtiligase Based Positive Selection		Wells	apoptosis_U266_bortezomib_induced	23264352

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...SSGEWY	101	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000428362
...CENCGA	124	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000429990
...RVGAKF	143	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000428943
...NIAPDE	152	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC11022
...SFLGQ	586	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
GRAB_HUMAN	152	APDE.\|.EHVQ	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:Complementary positional proteo... (M14.017)	20526345,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)