Q9H7Z3: Protein NRDE2 homolog

General Information

Protein names	- Protein NRDE2 homolog
Gene names	NRDE2
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q9H7Z3

5 N-termini

3 C-termini

1 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MALFPAFAGL SEAPDGGSSR KELDWLSNPS FCVGSITSLS QQTEAAPAHV SEGLPLTRSH
        70         80         90        100        110        120
LKSESSDESD TNKKLKQTSR KKKKEKKKKR KHQHHKKTKR KHGPSSSSRS ETDTDSEKDK
       130        140        150        160        170        180
PSRGVGGSKK ESEEPNQGNN AAADTGHRFV WLEDIQAVTG ETFRTDKKPD PANWEYKSLY
       190        200        210        220        230        240
RGDIARYKRK GDSCLGINPK KQCISWEGTS TEKKHSRKQV ERYFTKKSVG LMNIDGVAIS
       250        260        270        280        290        300
SKTEPPSSEP ISFIPVKDLE DAAPVTTWLN PLGIYDQSTT HWLQGQGPPE QESKQPDAQP
       310        320        330        340        350        360
DSESAALKAK VEEFNRRVRE NPRDTQLWMA FVAFQDEVMK SPGLYAIEEG EQEKRKRSLK
       370        380        390        400        410        420
LILEKKLAIL ERAIESNQSS VDLKLAKLKL CTEFWEPSTL VKEWQKLIFL HPNNTALWQK
       430        440        450        460        470        480
YLLFCQSQFS TFSISKIHSL YGKCLSTLSA VKDGSILSHP ALPGTEEAMF ALFLQQCHFL
       490        500        510        520        530        540
RQAGHSEKAI SLFQAMVDFT FFKPDSVKDL PTKGQVEFFE PFWDSGEPRA GEKGARGWKA
       550        560        570        580        590        600
WMHQQERGGW VVINPDEDDD EPEEDDQEIK DKTLPRWQIW LAAERSRDQR HWRPWRPDKT
       610        620        630        640        650        660
KKQTEEDCED PERQVLFDDI GQSLIRLSSH DLQFQLVEAF LQFLGVPSGF TPPASCLYLA
       670        680        690        700        710        720
MDENSIFDNG LYDEKPLTFF NPLFSGASCV GRMDRLGYPR WTRGQNREGE EFIRNVFHLV
       730        740        750        760        770        780
MPLFSGKEKS QLCFSWLQYE IAKVIWCLHT KNKKRLKSQG KNCKKLAKNL LKEPENCNNF
       790        800        810        820        830        840
CLWKQYAHLE WLLGNTEDAR KVFDTALGMA GSRELKDSDL CELSLLYAEL EVELSPEVRR
       850        860        870        880        890        900
AATARAVHIL TKLTESSPYG PYTGQVLAVH ILKARKAYEH ALQDCLGDSC VSNPAPTDSC
       910        920        930        940        950        960
SRLISLAKCF MLFQYLTIGI DAAVQIYEQV FAKLNSSVFP EGSGEGDSAS SQSWTSVLEA
       970        980        990       1000       1010       1020
ITLMHTSLLR FHMKVSVYPL APLREALSQA LKLYPGNQVL WRSYVQIQNK SHSASKTRRF
      1030       1040       1050       1060       1070       1080
FDTITRSAKP LEPWLFAIEA EKLRKRLVET VQRLDGREIH ATIPETGLMH RIQALFENAM
      1090       1100       1110       1120       1130       1140
RSDSGSQCPL LWRMYLNFLV SLGNKERSKG VFYKALQNCP WAKVLYLDAV EYFPDEMQEI
      1150       1160
LDLMTEKELR VRLPLEELEL LLED

Isoforms

Sequence View

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Evidence Names:

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Protein Neighborhood

Domains & Features

5 N-termini - 3 C-termini - 1 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q9H7Z3-2-unknown	MALFPA...	1		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q9H7Z3-2-Acetylation	ALFPAF...	2	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q9H7Z3-2-Acetylation	ALFPAF...	2	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345
Q9H7Z3-2-Acetylation	ALFPAF...	2	acetylation-		other		CNRS/ISV	Large_scale_NTA_Human
Q9H7Z3-2-Acetylation	ALFPAF...	2	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345
Q9H7Z3-232-unknown	MNIDGV...	232		inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000350579
Q9H7Z3-432-unknown	FSISKI...	432		inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000452071
Q9H7Z3-557-unknown	EDDDEP...	557		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC13325

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...VINPDE	556	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC13325
...GQSLIR	625	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000452071
...LLLED	1164	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
GRAB_HUMAN	556	NPDE.\|.EDDD	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:Analysis of protein processing ... (S01.010)	18836177,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)