O15066: Kinesin-like protein KIF3B

General Information

Protein names	- Kinesin-like protein KIF3B - HH0048 - Microtubule plus end-directed kinesin motor 3B - Kinesin-like protein KIF3B, N-terminally processed
Gene names	KIF3B
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	O15066

6 N-termini

4 C-termini

3 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MSKLKSSESV RVVVRCRPMN GKEKAASYDK VVDVDVKLGQ VSVKNPKGTA HEMPKTFTFD
        70         80         90        100        110        120
AVYDWNAKQF ELYDETFRPL VDSVLQGFNG TIFAYGQTGT GKTYTMEGIR GDPEKRGVIP
       130        140        150        160        170        180
NSFDHIFTHI SRSQNQQYLV RASYLEIYQE EIRDLLSKDQ TKRLELKERP DTGVYVKDLS
       190        200        210        220        230        240
SFVTKSVKEI EHVMNVGNQN RSVGATNMNE HSSRSHAIFV ITIECSEVGL DGENHIRVGK
       250        260        270        280        290        300
LNLVDLAGSE RQAKTGAQGE RLKEATKINL SLSALGNVIS ALVDGKSTHI PYRDSKLTRL
       310        320        330        340        350        360
LQDSLGGNAK TVMVANVGPA SYNVEETLTT LRYANRAKNI KNKPRVNEDP KDALLREFQE
       370        380        390        400        410        420
EIARLKAQLE KRSIGRRKRR EKRREGGGSG GGGEEEEEEG EEGEEEGDDK DDYWREQQEK
       430        440        450        460        470        480
LEIEKRAIVE DHSLVAEEKM RLLKEKEKKM EDLRREKDAA EMLGAKIKAM ESKLLVGGKN
       490        500        510        520        530        540
IVDHTNEQQK ILEQKRQEIA EQKRREREIQ QQMESRDEET LELKETYSSL QQEVDIKTKK
       550        560        570        580        590        600
LKKLFSKLQA VKAEIHDLQE EHIKERQELE QTQNELTREL KLKHLIIENF IPLEEKSKIM
       610        620        630        640        650        660
NRAFFDEEED HWKLHPITRL ENQQMMKRPV SAVGYKRPLS QHARMSMMIR PEARYRAENI
       670        680        690        700        710        720
VLLELDMPSR TTRDYEGPAI APKVQAALDA ALQDEDEIQV DASSFESTAN KKSKARPKSG
       730        740
RKSGSSSSSS GTPASQLYPQ SRGLVPK

Isoforms

- Isoform 2 of Kinesin-like protein KIF3B

Sequence View

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

6 N-termini - 4 C-termini - 3 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
O15066-1-Acetylation	MSKLKS...	1	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
O15066-2-Acetylation	SKLKSS...	2	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
O15066-2-Acetylation	SKLKSS...	2	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345
O15066-2-Acetylation	SKLKSS...	2	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345
O15066-313-unknown	MVANVG...	313		inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000406287
O15066-421-unknown	LEIEKR...	421		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC10701
O15066-722-unknown	KSGSSS...	722		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC18221
O15066-739-unknown	PQSRGL...	739		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC18222

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...EQQEKL	420	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC10701
...PKSGRK	721	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC18221
...ASQLYP	738	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC18222
...GLVPK	747	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
GRAB_HUMAN	420	QEKL.\|.LEIE	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:Analysis of protein processing ... (S01.010)	18836177,
MEP1B_HUMAN	721	SGRK.\|.KSGS	inferred from experiment	unknown	MEROPS	Overall CM	Becker-Pauly C et al.:Proteomic analyses reveal an ac... (M12.002)	21693781,
MEP1B_HUMAN	738	QLYP.\|.PQSR	inferred from experiment	unknown	MEROPS	Overall CM	Becker-Pauly C et al.:Proteomic analyses reveal an ac... (M12.002)	21693781,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)