Q15291: Retinoblastoma-binding protein 5

General Information

Protein names	- Retinoblastoma-binding protein 5 - RBBP-5 - Retinoblastoma-binding protein RBQ-3
Gene names	RBBP5
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q15291

3 N-termini

3 C-termini

2 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MNLELLESFG QNYPEEADGT LDCISMALTC TFNRWGTLLA VGCNDGRIVI WDFLTRGIAK
        70         80         90        100        110        120
IISAHIHPVC SLCWSRDGHK LVSASTDNIV SQWDVLSGDC DQRFRFPSPI LKVQYHPRDQ
       130        140        150        160        170        180
NKVLVCPMKS APVMLTLSDS KHVVLPVDDD SDLNVVASFD RRGEYIYTGN AKGKILVLKT
       190        200        210        220        230        240
DSQDLVASFR VTTGTSNTTA IKSIEFARKG SCFLINTADR IIRVYDGREI LTCGRDGEPE
       250        260        270        280        290        300
PMQKLQDLVN RTPWKKCCFS GDGEYIVAGS ARQHALYIWE KSIGNLVKIL HGTRGELLLD
       310        320        330        340        350        360
VAWHPVRPII ASISSGVVSI WAQNQVENWS AFAPDFKELD ENVEYEERES EFDIEDEDKS
       370        380        390        400        410        420
EPEQTGADAA EDEEVDVTSV DPIAAFCSSD EELEDSKALL YLPIAPEVED PEENPYGPPP
       430        440        450        460        470        480
DAVQTSLMDE GASSEKKRQS SADGSQPPKK KPKTTNIELQ GVPNDEVHPL LGVKGDGKSK
       490        500        510        520        530
KKQAGRPKGS KGKEKDSPFK PKLYKGDRGL PLEGSAKGKV QAELSQPLTA GGAISELL

Isoforms

- Isoform 2 of Retinoblastoma-binding protein 5

Sequence View

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Protein Neighborhood

Domains & Features

3 N-termini - 3 C-termini - 2 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
Q15291-1-unknown	MNLELL...	1	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q15291-1-unknown	MNLELL...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt87040
Q15291-336-unknown	FKELDE...	336	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC12358
Q15291-336-unknown	FKELDE...	336	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt150634
Q15291-428-unknown	MDEGAS...	428	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC14530
Q15291-428-unknown	MDEGAS...	428	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt152449

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...AFAPDF	335	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC12358
...AFAPDF	335	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt134032
...VQTSLM	427	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC14530
...VQTSLM	427	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt135859
...ISELL	538	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
GRAB_HUMAN	335	APDF.\|.FKEL	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:Complementary positional proteo... (M14.017)	20526345,
GRAM_HUMAN	427	TSLM.\|.MDEG	inferred from experiment	unknown	MEROPS	Bovenschen N	de Poot SA et al.:Human and mouse granzyme M disp... (S01.139)	21564021,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)