Q6Y7W6: GRB10-interacting GYF protein 2 {ECO:0000303|PubMed:12771153}

General Information

Protein names	- GRB10-interacting GYF protein 2 {ECO:0000303\|PubMed:12771153} - PERQ amino acid-rich with GYF domain-containing protein 2 - Trinucleotide repeat-containing gene 15 protein {ECO:0000303\|PubMed:18358451}
Gene names	GIGYF2
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q6Y7W6

11 N-termini

4 C-termini

2 Cleavages

0 Substrates

Sequence

Isoforms

- Isoform 2 of PERQ amino acid-rich with GYF domain-containing protein 2 - Isoform 3 of PERQ amino acid-rich with GYF domain-containing protein 2 - Isoform 4 of PERQ amino acid-rich with GYF domain-containing protein 2 - Isoform 2 of GRB10-interacting GYF protein 2 - Isoform 3 of GRB10-interacting GYF protein 2 - Isoform 4 of GRB10-interacting GYF protein 2

Sequence View

        10         20         30         40         50         60
MAAETQTLNF GPEWLRALSS GGSITSPPLS PALPKYKLAD YRYGREEMLA LFLKDNKIPS
        70         80         90        100        110        120
DLLDKEFLPI LQEEPLPPLA LVPFTEEEQR NFSMSVNSAA VLRLTGRGGG GTVVGAPRGR
       130        140        150        160        170        180
SSSRGRGRGR GECGFYQRSF DEVEGVFGRG GGREMHRSQS WEERGDRRFE KPGRKDVGRP
       190        200        210        220        230        240
NFEEGGPTSV GRKHEFIRSE SENWRIFREE QNGEDEDGGW RLAGSRRDGE RWRPHSPDGP
       250        260        270        280        290        300
RSAGWREHME RRRRFEFDFR DRDDERGYRR VRSGSGSIDD DRDSLPEWCL EDAEEEMGTF
       310        320        330        340        350        360
DSSGAFLSLK KVQKEPIPEE QEMDFRPVDE GEECSDSEGS HNEEAKEPDK TNKKEGEKTD
       370        380        390        400        410        420
RVGVEASEET PQTSSSSARP GTPSDHQSQE ASQFERKDEP KTEQTEKAEE ETRMENSLPA
       430        440        450        460        470        480
KVPSRGDEMV ADVQQPLSQI PSDTASPLLI LPPPVPNPSP TLRPVETPVV GAPGMGSVST
       490        500        510        520        530        540
EPDDEEGLKH LEQQAEKMVA YLQDSALDDE RLASKLQEHR AKGVSIPLMH EAMQKWYYKD
       550        560        570        580        590        600
PQGEIQGPFN NQEMAEWFQA GYFTMSLLVK RACDESFQPL GDIMKMWGRV PFSPGPAPPP
       610        620        630        640        650        660
HMGELDQERL TRQQELTALY QMQHLQYQQF LIQQQYAQVL AQQQKAALSS QQQQQLALLL
       670        680        690        700        710        720
QQFQTLKMRI SDQNIIPSVT RSVSVPDTGS IWELQPTASQ PTVWEGGSVW DLPLDTTTPG
       730        740        750        760        770        780
PALEQLQQLE KAKAAKLEQE RREAEMRAKR EEEERKRQEE LRRQQEEILR RQQEEERKRR
       790        800        810        820        830        840
EEEELARRKQ EEALRRQREQ EIALRRQREE EERQQQEEAL RRLEERRREE EERRKQEELL
       850        860        870        880        890        900
RKQEEEAAKW AREEEEAQRR LEENRLRMEE EAARLRHEEE ERKRKELEVQ RQKELMRQRQ
       910        920        930        940        950        960
QQQEALRRLQ QQQQQQQLAQ MKLPSSSTWG QQSNTTACQS QATLSLAEIQ KLEEERERQL
       970        980        990       1000       1010       1020
REEQRRQQRE LMKALQQQQQ QQQQKLSGWG NVSKPSGTTK SLLEIQQEEA RQMQKQQQQQ
      1030       1040       1050       1060       1070       1080
QQHQQPNRAR NNTHSNLHTS IGNSVWGSIN TGPPNQWASD LVSSIWSNAD TKNSNMGFWD
      1090       1100       1110       1120       1130       1140
DAVKEVGPRN STNKNKNNAS LSKSVGVSNR QNKKVEEEEK LLKLFQGVNK AQDGFTQWCE
      1150       1160       1170       1180       1190       1200
QMLHALNTAN NLDVPTFVSF LKEVESPYEV HDYIRAYLGD TSEAKEFAKQ FLERRAKQKA
      1210       1220       1230       1240       1250       1260
NQQRQQQQLP QQQQQQPPQQ PPQQPQQQDS VWGMNHSTLH SVFQTNQSNN QQSNFEAVQS
      1270       1280       1290
GKKKKKQKMV RADPSLLGFS VNASSERLNM GEIETLDDY         10         20         30         40         50         60
MAAETQTLNF GPEWLRALSS GGSITSPPLS PALPKYKLAD YRYGREEMLA LFLKDNKIPS
        70         80         90        100        110        120
DLLDKEFLPI LQEEPLPPLA LVPFTEEEQR NFSMSVNSAA VLRLTGRGGG GTVVGAPRGR
       130        140        150        160        170        180
SSSRGRGRGR GECGFYQRSF DEVEGVFGRG GGREMHRSQS WEERGDRRFE KPGRKDVGRP
       190        200        210        220        230        240
NFEEGGPTSV GRKHEFIRSE SENWRIFREE QNGEDEDGGW RLAGSRRDGE RWRPHSPDGP
       250        260        270        280        290        300
RSAGWREHME RRRRFEFDFR DRDDERGYRR VRSGSGSIDD DRDSLPEWCL EDAEEEMGTF
       310        320        330        340        350        360
DSSGAFLSLK KVQKEPIPEE QEMDFRPVDE GEECSDSEGS HNEEAKEPDK TNKKEGEKTD
       370        380        390        400        410        420
RVGVEASEET PQTSSSSARP GTPSDHQSQE ASQFERKDEP KTEQTEKAEE ETRMENSLPA
       430        440        450        460        470        480
KVPSRGDEMV ADVQQPLSQI PSDTASPLLI LPPPVPNPSP TLRPVETPVV GAPGMGSVST
       490        500        510        520        530        540
EPDDEEGLKH LEQQAEKMVA YLQDSALDDE RLASKLQEHR AKGVSIPLMH EAMQKWYYKD
       550        560        570        580        590        600
PQGEIQGPFN NQEMAEWFQA GYFTMSLLVK RACDESFQPL GDIMKMWGRV PFSPGPAPPP
       610        620        630        640        650        660
HMGELDQERL TRQQELTALY QMQHLQYQQF LIQQQYAQVL AQQQKAALSS QQQQQLALLL
       670        680        690        700        710        720
QQFQTLKMRI SDQNIIPSVT RSVSVPDTGS IWELQPTASQ PTVWEGGSVW DLPLDTTTPG
       730        740        750        760        770        780
PALEQLQQLE KAKAAKLEQE RREAEMRAKR EEEERKRQEE LRRQQEEILR RQQEEERKRR
       790        800        810        820        830        840
EEEELARRKQ EEALRRQREQ EIALRRQREE EERQQQEEAL RRLEERRREE EERRKQEELL
       850        860        870        880        890        900
RKQEEEAAKW AREEEEAQRR LEENRLRMEE EAARLRHEEE ERKRKELEVQ RQKELMRQRQ
       910        920        930        940        950        960
QQQEALRRLQ QQQQQQQLAQ MKLPSSSTWG QQSNTTACQS QATLSLAEIQ KLEEERERQL
       970        980        990       1000       1010       1020
REEQRRQQRE LMKALQQQQQ QQQQKLSGWG NVSKPSGTTK SLLEIQQEEA RQMQKQQQQQ
      1030       1040       1050       1060       1070       1080
QQHQQPNRAR NNTHSNLHTS IGNSVWGSIN TGPPNQWASD LVSSIWSNAD TKNSNMGFWD
      1090       1100       1110       1120       1130       1140
DAVKEVGPRN STNKNKNNAS LSKSVGVSNR QNKKVEEEEK LLKLFQGVNK AQDGFTQWCE
      1150       1160       1170       1180       1190       1200
QMLHALNTAN NLDVPTFVSF LKEVESPYEV HDYIRAYLGD TSEAKEFAKQ FLERRAKQKA
      1210       1220       1230       1240       1250       1260
NQQRQQQQLP QQQQQQPPQQ PPQQPQQQDS VWGMNHSTLH SVFQTNQSNN QQSNFEAVQS
      1270       1280       1290
GKKKKKQKMV RADPSLLGFS VNASSERLNM GEIETLDDY         10         20         30         40         50         60
MAAETQTLNF GPEWLRALSS GGSITSPPLS PALPKYKLAD YRYGREEMLA LFLKDNKIPS
        70         80         90        100        110        120
DLLDKEFLPI LQEEPLPPLA LVPFTEEEQR NFSMSVNSAA VLRLTGRGGG GTVVGAPRGR
       130        140        150        160        170        180
SSSRGRGRGR GECGFYQRSF DEVEGVFGRG GGREMHRSQS WEERGDRRFE KPGRKDVGRP
       190        200        210        220        230        240
NFEEGGPTSV GRKHEFIRSE SENWRIFREE QNGEDEDGGW RLAGSRRDGE RWRPHSPDGP
       250        260        270        280        290        300
RSAGWREHME RRRRFEFDFR DRDDERGYRR VRSGSGSIDD DRDSLPEWCL EDAEEEMGTF
       310        320        330        340        350        360
DSSGAFLSLK KVQKEPIPEE QEMDFRPVDE GEECSDSEGS HNEEAKEPDK TNKKEGEKTD
       370        380        390        400        410        420
RVGVEASEET PQTSSSSARP GTPSDHQSQE ASQFERKDEP KTEQTEKAEE ETRMENSLPA
       430        440        450        460        470        480
KVPSRGDEMV ADVQQPLSQI PSDTASPLLI LPPPVPNPSP TLRPVETPVV GAPGMGSVST
       490        500        510        520        530        540
EPDDEEGLKH LEQQAEKMVA YLQDSALDDE RLASKLQEHR AKGVSIPLMH EAMQKWYYKD
       550        560        570        580        590        600
PQGEIQGPFN NQEMAEWFQA GYFTMSLLVK RACDESFQPL GDIMKMWGRV PFSPGPAPPP
       610        620        630        640        650        660
HMGELDQERL TRQQELTALY QMQHLQYQQF LIQQQYAQVL AQQQKAALSS QQQQQLALLL
       670        680        690        700        710        720
QQFQTLKMRI SDQNIIPSVT RSVSVPDTGS IWELQPTASQ PTVWEGGSVW DLPLDTTTPG
       730        740        750        760        770        780
PALEQLQQLE KAKAAKLEQE RREAEMRAKR EEEERKRQEE LRRQQEEILR RQQEEERKRR
       790        800        810        820        830        840
EEEELARRKQ EEALRRQREQ EIALRRQREE EERQQQEEAL RRLEERRREE EERRKQEELL
       850        860        870        880        890        900
RKQEEEAAKW AREEEEAQRR LEENRLRMEE EAARLRHEEE ERKRKELEVQ RQKELMRQRQ
       910        920        930        940        950        960
QQQEALRRLQ QQQQQQQLAQ MKLPSSSTWG QQSNTTACQS QATLSLAEIQ KLEEERERQL
       970        980        990       1000       1010       1020
REEQRRQQRE LMKALQQQQQ QQQQKLSGWG NVSKPSGTTK SLLEIQQEEA RQMQKQQQQQ
      1030       1040       1050       1060       1070       1080
QQHQQPNRAR NNTHSNLHTS IGNSVWGSIN TGPPNQWASD LVSSIWSNAD TKNSNMGFWD
      1090       1100       1110       1120       1130       1140
DAVKEVGPRN STNKNKNNAS LSKSVGVSNR QNKKVEEEEK LLKLFQGVNK AQDGFTQWCE
      1150       1160       1170       1180       1190       1200
QMLHALNTAN NLDVPTFVSF LKEVESPYEV HDYIRAYLGD TSEAKEFAKQ FLERRAKQKA
      1210       1220       1230       1240       1250       1260
NQQRQQQQLP QQQQQQPPQQ PPQQPQQQDS VWGMNHSTLH SVFQTNQSNN QQSNFEAVQS
      1270       1280       1290
GKKKKKQKMV RADPSLLGFS VNASSERLNM GEIETLDDY         10         20         30         40         50         60
MAAETQTLNF GPEWLRALSS GGSITSPPLS PALPKYKLAD YRYGREEMLA LFLKDNKIPS
        70         80         90        100        110        120
DLLDKEFLPI LQEEPLPPLA LVPFTEEEQR NFSMSVNSAA VLRLTGRGGG GTVVGAPRGR
       130        140        150        160        170        180
SSSRGRGRGR GECGFYQRSF DEVEGVFGRG GGREMHRSQS WEERGDRRFE KPGRKDVGRP
       190        200        210        220        230        240
NFEEGGPTSV GRKHEFIRSE SENWRIFREE QNGEDEDGGW RLAGSRRDGE RWRPHSPDGP
       250        260        270        280        290        300
RSAGWREHME RRRRFEFDFR DRDDERGYRR VRSGSGSIDD DRDSLPEWCL EDAEEEMGTF
       310        320        330        340        350        360
DSSGAFLSLK KVQKEPIPEE QEMDFRPVDE GEECSDSEGS HNEEAKEPDK TNKKEGEKTD
       370        380        390        400        410        420
RVGVEASEET PQTSSSSARP GTPSDHQSQE ASQFERKDEP KTEQTEKAEE ETRMENSLPA
       430        440        450        460        470        480
KVPSRGDEMV ADVQQPLSQI PSDTASPLLI LPPPVPNPSP TLRPVETPVV GAPGMGSVST
       490        500        510        520        530        540
EPDDEEGLKH LEQQAEKMVA YLQDSALDDE RLASKLQEHR AKGVSIPLMH EAMQKWYYKD
       550        560        570        580        590        600
PQGEIQGPFN NQEMAEWFQA GYFTMSLLVK RACDESFQPL GDIMKMWGRV PFSPGPAPPP
       610        620        630        640        650        660
HMGELDQERL TRQQELTALY QMQHLQYQQF LIQQQYAQVL AQQQKAALSS QQQQQLALLL
       670        680        690        700        710        720
QQFQTLKMRI SDQNIIPSVT RSVSVPDTGS IWELQPTASQ PTVWEGGSVW DLPLDTTTPG
       730        740        750        760        770        780
PALEQLQQLE KAKAAKLEQE RREAEMRAKR EEEERKRQEE LRRQQEEILR RQQEEERKRR
       790        800        810        820        830        840
EEEELARRKQ EEALRRQREQ EIALRRQREE EERQQQEEAL RRLEERRREE EERRKQEELL
       850        860        870        880        890        900
RKQEEEAAKW AREEEEAQRR LEENRLRMEE EAARLRHEEE ERKRKELEVQ RQKELMRQRQ
       910        920        930        940        950        960
QQQEALRRLQ QQQQQQQLAQ MKLPSSSTWG QQSNTTACQS QATLSLAEIQ KLEEERERQL
       970        980        990       1000       1010       1020
REEQRRQQRE LMKALQQQQQ QQQQKLSGWG NVSKPSGTTK SLLEIQQEEA RQMQKQQQQQ
      1030       1040       1050       1060       1070       1080
QQHQQPNRAR NNTHSNLHTS IGNSVWGSIN TGPPNQWASD LVSSIWSNAD TKNSNMGFWD
      1090       1100       1110       1120       1130       1140
DAVKEVGPRN STNKNKNNAS LSKSVGVSNR QNKKVEEEEK LLKLFQGVNK AQDGFTQWCE
      1150       1160       1170       1180       1190       1200
QMLHALNTAN NLDVPTFVSF LKEVESPYEV HDYIRAYLGD TSEAKEFAKQ FLERRAKQKA
      1210       1220       1230       1240       1250       1260
NQQRQQQQLP QQQQQQPPQQ PPQQPQQQDS VWGMNHSTLH SVFQTNQSNN QQSNFEAVQS
      1270       1280       1290
GKKKKKQKMV RADPSLLGFS VNASSERLNM GEIETLDDY         10         20         30         40         50         60
MAAETQTLNF GPEWLRALSS GGSITSPPLS PALPKYKLAD YRYGREEMLA LFLKDNKIPS
        70         80         90        100        110        120
DLLDKEFLPI LQEEPLPPLA LVPFTEEEQR NFSMSVNSAA VLRLTGRGGG GTVVGAPRGR
       130        140        150        160        170        180
SSSRGRGRGR GECGFYQRSF DEVEGVFGRG GGREMHRSQS WEERGDRRFE KPGRKDVGRP
       190        200        210        220        230        240
NFEEGGPTSV GRKHEFIRSE SENWRIFREE QNGEDEDGGW RLAGSRRDGE RWRPHSPDGP
       250        260        270        280        290        300
RSAGWREHME RRRRFEFDFR DRDDERGYRR VRSGSGSIDD DRDSLPEWCL EDAEEEMGTF
       310        320        330        340        350        360
DSSGAFLSLK KVQKEPIPEE QEMDFRPVDE GEECSDSEGS HNEEAKEPDK TNKKEGEKTD
       370        380        390        400        410        420
RVGVEASEET PQTSSSSARP GTPSDHQSQE ASQFERKDEP KTEQTEKAEE ETRMENSLPA
       430        440        450        460        470        480
KVPSRGDEMV ADVQQPLSQI PSDTASPLLI LPPPVPNPSP TLRPVETPVV GAPGMGSVST
       490        500        510        520        530        540
EPDDEEGLKH LEQQAEKMVA YLQDSALDDE RLASKLQEHR AKGVSIPLMH EAMQKWYYKD
       550        560        570        580        590        600
PQGEIQGPFN NQEMAEWFQA GYFTMSLLVK RACDESFQPL GDIMKMWGRV PFSPGPAPPP
       610        620        630        640        650        660
HMGELDQERL TRQQELTALY QMQHLQYQQF LIQQQYAQVL AQQQKAALSS QQQQQLALLL
       670        680        690        700        710        720
QQFQTLKMRI SDQNIIPSVT RSVSVPDTGS IWELQPTASQ PTVWEGGSVW DLPLDTTTPG
       730        740        750        760        770        780
PALEQLQQLE KAKAAKLEQE RREAEMRAKR EEEERKRQEE LRRQQEEILR RQQEEERKRR
       790        800        810        820        830        840
EEEELARRKQ EEALRRQREQ EIALRRQREE EERQQQEEAL RRLEERRREE EERRKQEELL
       850        860        870        880        890        900
RKQEEEAAKW AREEEEAQRR LEENRLRMEE EAARLRHEEE ERKRKELEVQ RQKELMRQRQ
       910        920        930        940        950        960
QQQEALRRLQ QQQQQQQLAQ MKLPSSSTWG QQSNTTACQS QATLSLAEIQ KLEEERERQL
       970        980        990       1000       1010       1020
REEQRRQQRE LMKALQQQQQ QQQQKLSGWG NVSKPSGTTK SLLEIQQEEA RQMQKQQQQQ
      1030       1040       1050       1060       1070       1080
QQHQQPNRAR NNTHSNLHTS IGNSVWGSIN TGPPNQWASD LVSSIWSNAD TKNSNMGFWD
      1090       1100       1110       1120       1130       1140
DAVKEVGPRN STNKNKNNAS LSKSVGVSNR QNKKVEEEEK LLKLFQGVNK AQDGFTQWCE
      1150       1160       1170       1180       1190       1200
QMLHALNTAN NLDVPTFVSF LKEVESPYEV HDYIRAYLGD TSEAKEFAKQ FLERRAKQKA
      1210       1220       1230       1240       1250       1260
NQQRQQQQLP QQQQQQPPQQ PPQQPQQQDS VWGMNHSTLH SVFQTNQSNN QQSNFEAVQS
      1270       1280       1290
GKKKKKQKMV RADPSLLGFS VNASSERLNM GEIETLDDY         10         20         30         40         50         60
MAAETQTLNF GPEWLRALSS GGSITSPPLS PALPKYKLAD YRYGREEMLA LFLKDNKIPS
        70         80         90        100        110        120
DLLDKEFLPI LQEEPLPPLA LVPFTEEEQR NFSMSVNSAA VLRLTGRGGG GTVVGAPRGR
       130        140        150        160        170        180
SSSRGRGRGR GECGFYQRSF DEVEGVFGRG GGREMHRSQS WEERGDRRFE KPGRKDVGRP
       190        200        210        220        230        240
NFEEGGPTSV GRKHEFIRSE SENWRIFREE QNGEDEDGGW RLAGSRRDGE RWRPHSPDGP
       250        260        270        280        290        300
RSAGWREHME RRRRFEFDFR DRDDERGYRR VRSGSGSIDD DRDSLPEWCL EDAEEEMGTF
       310        320        330        340        350        360
DSSGAFLSLK KVQKEPIPEE QEMDFRPVDE GEECSDSEGS HNEEAKEPDK TNKKEGEKTD
       370        380        390        400        410        420
RVGVEASEET PQTSSSSARP GTPSDHQSQE ASQFERKDEP KTEQTEKAEE ETRMENSLPA
       430        440        450        460        470        480
KVPSRGDEMV ADVQQPLSQI PSDTASPLLI LPPPVPNPSP TLRPVETPVV GAPGMGSVST
       490        500        510        520        530        540
EPDDEEGLKH LEQQAEKMVA YLQDSALDDE RLASKLQEHR AKGVSIPLMH EAMQKWYYKD
       550        560        570        580        590        600
PQGEIQGPFN NQEMAEWFQA GYFTMSLLVK RACDESFQPL GDIMKMWGRV PFSPGPAPPP
       610        620        630        640        650        660
HMGELDQERL TRQQELTALY QMQHLQYQQF LIQQQYAQVL AQQQKAALSS QQQQQLALLL
       670        680        690        700        710        720
QQFQTLKMRI SDQNIIPSVT RSVSVPDTGS IWELQPTASQ PTVWEGGSVW DLPLDTTTPG
       730        740        750        760        770        780
PALEQLQQLE KAKAAKLEQE RREAEMRAKR EEEERKRQEE LRRQQEEILR RQQEEERKRR
       790        800        810        820        830        840
EEEELARRKQ EEALRRQREQ EIALRRQREE EERQQQEEAL RRLEERRREE EERRKQEELL
       850        860        870        880        890        900
RKQEEEAAKW AREEEEAQRR LEENRLRMEE EAARLRHEEE ERKRKELEVQ RQKELMRQRQ
       910        920        930        940        950        960
QQQEALRRLQ QQQQQQQLAQ MKLPSSSTWG QQSNTTACQS QATLSLAEIQ KLEEERERQL
       970        980        990       1000       1010       1020
REEQRRQQRE LMKALQQQQQ QQQQKLSGWG NVSKPSGTTK SLLEIQQEEA RQMQKQQQQQ
      1030       1040       1050       1060       1070       1080
QQHQQPNRAR NNTHSNLHTS IGNSVWGSIN TGPPNQWASD LVSSIWSNAD TKNSNMGFWD
      1090       1100       1110       1120       1130       1140
DAVKEVGPRN STNKNKNNAS LSKSVGVSNR QNKKVEEEEK LLKLFQGVNK AQDGFTQWCE
      1150       1160       1170       1180       1190       1200
QMLHALNTAN NLDVPTFVSF LKEVESPYEV HDYIRAYLGD TSEAKEFAKQ FLERRAKQKA
      1210       1220       1230       1240       1250       1260
NQQRQQQQLP QQQQQQPPQQ PPQQPQQQDS VWGMNHSTLH SVFQTNQSNN QQSNFEAVQS
      1270       1280       1290
GKKKKKQKMV RADPSLLGFS VNASSERLNM GEIETLDDY

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

11 N-termini - 4 C-termini - 2 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q6Y7W6-1-unknown	MAAETQ...	1		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt84885
Q6Y7W6-1-unknown	MAAETQ...	1		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt84886
Q6Y7W6-1-unknown	MAAETQ...	1		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt84887
Q6Y7W6-2-unknown	MAAETQ...	1		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q6Y7W6-2-Acetylation	AAETQT...	2	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q6Y7W6-2-Acetylation	AAETQT...	2	acetylation-		other		CNRS/ISV	Large_scale_NTA_Human
Q6Y7W6-2-Acetylation	AAETQT...	2	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345
Q6Y7W6-2-Acetylation	AAETQT...	2	acetylation-	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt111327
Q6Y7W6-2-Acetylation	AAETQT...	2	acetylation-	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt111328
Q6Y7W6-2-Acetylation	AAETQT...	2	acetylation-	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt111329
Q6Y7W6-366-unknown	ASEETP...	366		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC12637
Q6Y7W6-366-unknown	ASEETP...	366		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt151166
Q6Y7W6-366-unknown	ASEETP...	366		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt151167
Q6Y7W6-366-unknown	ASEETP...	366		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt199178
Q6Y7W6-474-	GMGSVS...	474			Subtiligase Based Positive Selection		Wells	apoptotic_MM1SDBJurkat_Mix	23264352
Q6Y7W6-474-unknown	GMGSVS...	474		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt177169
Q6Y7W6-474-unknown	GMGSVS...	474		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt177170
Q6Y7W6-474-unknown	GMGSVS...	474		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt177171
Q6Y7W6-477-	SVSTEP...	477			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
Q6Y7W6-477-unknown	SVSTEP...	477		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt174397
Q6Y7W6-477-unknown	SVSTEP...	477		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt174398
Q6Y7W6-477-unknown	SVSTEP...	477		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt174399
Q6Y7W6-1001-unknown	SLLEIQ...	1001			unknown			Mahrus S. et al.: nonapototic Jurkat cells, Global Sequencing of Proteolytic Cleavage...	18722006
Q6Y7W6-1001-unknown	SLLEIQ...	1001		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt160064
Q6Y7W6-1001-unknown	SLLEIQ...	1001		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt160065
Q6Y7W6-1001-unknown	SLLEIQ...	1001		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt160066
Q6Y7W6-1001-	SLLEIQ...	1001			Subtiligase Based Positive Selection		Wells	Jurkat_untreated	23264352
Q6Y7W6-1283-unknown	ASSERL...	1283		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC12640
Q6Y7W6-1283-unknown	ASSERL...	1283		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt157859
Q6Y7W6-1283-unknown	ASSERL...	1283		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt157867
Q6Y7W6-1283-unknown	ASSERL...	1283		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt157904

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
...RVGVEA	365	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC12637
...RVGVEA	365	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt134568
...RVGVEA	365	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt134569
...GFSVNA	1282	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC12640
...GFSVNA	1282	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt141356
...GFSVNA	1282	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt141364
...GFSVNA	1282	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt141400
...TLDDY	1299		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345,
...TLDDY	1299	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
...TLDDY	1299	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt80504
...TLDDY	1299	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt80505
...TLDDY	1299	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt80503
...TLDDY	1299		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345,

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
GRAB_HUMAN	365	GVEA.\|.ASEE	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:Analysis of protein processing ... (S01.010)	18836177,
GRAB_HUMAN	1282	SVNA.\|.ASSE	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:Analysis of protein processing ... (S01.010)	18836177,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)