Q96IZ7: Serine/Arginine-related protein 53

General Information

Protein names	- Serine/Arginine-related protein 53 - SRrp53 - Arginine/serine-rich coiled-coil protein 1
Gene names	RSRC1
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q96IZ7

5 N-termini

4 C-termini

4 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MGRRSSDTEE ESRSKRKKKH RRRSSSSSSS DSRTYSRKKG GRKSRSKSRS WSRDLQPRSH
        70         80         90        100        110        120
SYDRRRRHRS SSSSSYGSRR KRSRSRSRGR GKSYRVQRSR SKSRTRRSRS RPRLRSHSRS
       130        140        150        160        170        180
SERSSHRRTR SRSRDRERRK GRDKEKREKE KDKGKDKELH NIKRGESGNI KAGLEHLPPA
       190        200        210        220        230        240
EQAKARLQLV LEAAAKADEA LKAKERNEEE AKRRKEEDQA TLVEQVKRVK EIEAIESDSF
       250        260        270        280        290        300
VQQTFRSSKE VKKSVEPSEV KQATSTSGPA SAVADPPSTE KEIDPTSIPT AIKYQDDNSL
       310        320        330
AHPNLFIEKA DAEEKWFKRL IALRQERLMG SPVA

Isoforms

- Isoform 2 of Serine/Arginine-related protein 53

Sequence View

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Evidence Codes:

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Protein Neighborhood

Domains & Features

5 N-termini - 4 C-termini - 4 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q96IZ7-1-unknown	MGRRSS...	1	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q96IZ7-1-unknown	MGRRSS...	1	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt88290
Q96IZ7-175-unknown	EHLPPA...	175	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC14839
Q96IZ7-175-unknown	EHLPPA...	175	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt197850
Q96IZ7-190-unknown	VLEAAA...	190	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC14840
Q96IZ7-190-unknown	VLEAAA...	190	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt143988
Q96IZ7-239-unknown	SFVQQT...	239	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC13076
Q96IZ7-239-unknown	SFVQQT...	239	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC1339
Q96IZ7-239-unknown	SFVQQT...	239		unknown			Mahrus S. et al.: nonapototic Jurkat cells, Global Sequencing of Proteolytic Cleavage...	18722006
Q96IZ7-239-unknown	SFVQQT...	239		unknown			Mahrus S. et al.: apototic Jurkat cells, Global Sequencing of Proteolytic Cleavage...	18722006
Q96IZ7-239-unknown	SFVQQT...	239	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt145913
Q96IZ7-239-	SFVQQT...	239		Subtiligase Based Positive Selection		Wells	apoptotic_DB_Doxo	23264352
Q96IZ7-239-	SFVQQT...	239		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_Etoposide	23264352
Q96IZ7-239-	SFVQQT...	239		Subtiligase Based Positive Selection		Wells	Jurkat_untreated	23264352
Q96IZ7-239-	SFVQQT...	239		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
Q96IZ7-239-	SFVQQT...	239		Subtiligase Based Positive Selection		Wells	apoptotic_MM1s_bort	23264352
Q96IZ7-239-	SFVQQT...	239		Subtiligase Based Positive Selection		Wells	apoptotic_MM1SDBJurkat_Mix	23264352
Q96IZ7-239-	SFVQQT...	239		Subtiligase Based Positive Selection		Wells	apoptosis_U266_bortezomib_induced	23264352

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...IKAGLE	174	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC14839
...ARLQLV	189	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC14840
...ARLQLV	189	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt127231
...AIESDS	238	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC13076
...AIESDS	238	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC1339
...AIESDS	238	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt129209
...GSPVA	334	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...GSPVA	334	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt83908

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
GRAM_HUMAN	174	AGLE.\|.EHLP	inferred from experiment	unknown	MEROPS	Bovenschen N	de Poot SA et al.:Human and mouse granzyme M disp... (S01.139)	21564021,
GRAM_HUMAN	189	LQLV.\|.VLEA	inferred from experiment	unknown	MEROPS	Bovenschen N	de Poot SA et al.:Human and mouse granzyme M disp... (S01.139)	21564021,
GRAB_HUMAN	238	ESDS.\|.SFVQ	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:Complementary positional proteo... (M14.017)	20526345,
CASP1_HUMAN	238	ESDS.\|.SFVQ	inferred from experiment	unknown	MEROPS	Wells JA	Agard NJ et al.:Inflammatory stimuli regulate c... (C14.001)	20173201,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)