TopFIND 4.0

Q96AY2: Crossover junction endonuclease EME1

General Information

Protein names
- Crossover junction endonuclease EME1
- 3.1.22.-
- MMS4 homolog
- hMMS4
Gene names EME1
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID Q96AY2

2

N-termini

2

C-termini

1

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MALKKSSPSL DSGDSDSEEL PTFAFLKKEP SSTKRRQPER EEKIVVVDIS DCEASCPPAP 
        70         80         90        100        110        120 
ELFSPPVPEI AETVTQTQPV RLLSSESEDE EEFIPLAQRL TCKFLTHKQL SPEDSSSPVK 
       130        140        150        160        170        180 
SVLDHQNNEG ASCDWKKPFP KIPEVPLHDT PERSAADNKD LILDPCCQLP AYLSTCPGQS 
       190        200        210        220        230        240 
SSLAVTKTNS DILPPQKKTK PSQKVQGRGS HGCRQQRQAR QKESTLRRQE RKNAALVTRM 
       250        260        270        280        290        300 
KAQRPEECLK HIIVVLDPVL LQMEGGGQLL GALQTMECRC VIEAQAVPCS VTWRRRAGPS 
       310        320        330        340        350        360 
EDREDWVEEP TVLVLLRAEA FVSMIDNGKQ GSLDSTMKGK ETLQGFVTDI TAKTAGKALS 
       370        380        390        400        410        420 
LVIVDQEKCF SAQNPPRRGK QGANKQTKKQ QQRQPEASIG SMVSRVDAEE ALVDLQLHTE 
       430        440        450        460        470        480 
AQAQIVQSWK ELADFTCAFT KAVAEAPFKK LRDETTFSFC LESDWAGGVK VDLAGRGLAL 
       490        500        510        520        530        540 
VWRRQIQQLN RVSLEMASAV VNAYPSPQLL VQAYQQCFSD KERQNLLADI QVRRGEGVTS 
       550        560        570    
TSRRIGPELS RRIYLQMTTL QPHLSLDSAD 

Isoforms

- Isoform 2 of Crossover junction endonuclease EME1

Sequence View

        10         20         30         40         50         60 
MALKKSSPSL DSGDSDSEEL PTFAFLKKEP SSTKRRQPER EEKIVVVDIS DCEASCPPAP 
        70         80         90        100        110        120 
ELFSPPVPEI AETVTQTQPV RLLSSESEDE EEFIPLAQRL TCKFLTHKQL SPEDSSSPVK 
       130        140        150        160        170        180 
SVLDHQNNEG ASCDWKKPFP KIPEVPLHDT PERSAADNKD LILDPCCQLP AYLSTCPGQS 
       190        200        210        220        230        240 
SSLAVTKTNS DILPPQKKTK PSQKVQGRGS HGCRQQRQAR QKESTLRRQE RKNAALVTRM 
       250        260        270        280        290        300 
KAQRPEECLK HIIVVLDPVL LQMEGGGQLL GALQTMECRC VIEAQAVPCS VTWRRRAGPS 
       310        320        330        340        350        360 
EDREDWVEEP TVLVLLRAEA FVSMIDNGKQ GSLDSTMKGK ETLQGFVTDI TAKTAGKALS 
       370        380        390        400        410        420 
LVIVDQEKCF SAQNPPRRGK QGANKQTKKQ QQRQPEASIG SMVSRVDAEE ALVDLQLHTE 
       430        440        450        460        470        480 
AQAQIVQSWK ELADFTCAFT KAVAEAPFKK LRDETTFSFC LESDWAGGVK VDLAGRGLAL 
       490        500        510        520        530        540 
VWRRQIQQLN RVSLEMASAV VNAYPSPQLL VQAYQQCFSD KERQNLLADI QVRRGEGVTS 
       550        560        570    
TSRRIGPELS RRIYLQMTTL QPHLSLDSAD 



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Evidence Codes:


Methodology:


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Protease Assignment Confidence:


Evidence Names:


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Lab:



Protein Neighborhood

Domains & Features

2 N-termini - 2 C-termini - 1 Cleavages - 0 Substrates

N-termini

C-termini

Cleavages

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)