P19784: Casein kinase II subunit alpha'

General Information

Protein names	- Casein kinase II subunit alpha' - CK II alpha' - 2.7.11.1
Gene names	CSNK2A2
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	P19784

7 N-termini

4 C-termini

2 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MPGPAAGSRA RVYAEVNSLR SREYWDYEAH VPSWGNQDDY QLVRKLGRGK YSEVFEAINI
        70         80         90        100        110        120
TNNERVVVKI LKPVKKKKIK REVKILENLR GGTNIIKLID TVKDPVSKTP ALVFEYINNT
       130        140        150        160        170        180
DFKQLYQILT DFDIRFYMYE LLKALDYCHS KGIMHRDVKP HNVMIDHQQK KLRLIDWGLA
       190        200        210        220        230        240
EFYHPAQEYN VRVASRYFKG PELLVDYQMY DYSLDMWSLG CMLASMIFRR EPFFHGQDNY
       250        260        270        280        290        300
DQLVRIAKVL GTEELYGYLK KYHIDLDPHF NDILGQHSRK RWENFIHSEN RHLVSPEALD
       310        320        330        340        350
LLDKLLRYDH QQRLTAKEAM EHPYFYPVVK EQSQPCADNA VLSSGLTAAR

Isoforms

Sequence View

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Evidence Names:

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Protein Neighborhood

Domains & Features

7 N-termini - 4 C-termini - 2 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
P19784-1-unknown	MPGPAA...	1	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P19784-2-unknown	PGPAAG...	2		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345
P19784-2-unknown	PGPAAG...	2		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345
P19784-73-unknown	PVKKKK...	73	inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000456606
P19784-235-unknown	HGQDNY...	235	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC5651
P19784-294-	VSPEAL...	294		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_Etoposide	23264352
P19784-294-	VSPEAL...	294		Subtiligase Based Positive Selection		Wells	apopotic_Jurkat_FasL	23264352
P19784-294-unknown	VSPEAL...	294		unknown			Mahrus S. et al.: apototic Jurkat cells, Global Sequencing of Proteolytic Cleavage...	18722006
P19784-339-unknown	NAVLSS...	339	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC11321

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...DFDIRF	135	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000454874
...REPFFH	234	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC5651
...QPCADN	338	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC11321
...LTAAR	350	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
CATL1_HUMAN	234	PFFH.\|.HGQD	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,
GRAB_HUMAN	338	CADN.\|.NAVL	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:Complementary positional proteo... (M14.017)	20526345,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)