Q8TAK5: GA-binding protein subunit beta-2

General Information

Protein names	- GA-binding protein subunit beta-2 - GABP subunit beta-2 - GABPB-2
Gene names	GABPB2
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q8TAK5

5 N-termini

3 C-termini

2 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MSLVDLGKRL LEAARKGQDD EVRTLMANGA PFTTDWLGTS PLHLAAQYGH YSTAEVLLRA
        70         80         90        100        110        120
GVSRDARTKV DRTPLHMAAA DGHAHIVELL VRNGADVNAK DMLKMTALHW ATERHHRDVV
       130        140        150        160        170        180
ELLIKYGADV HAFSKFDKSA FDIALEKNNA EILVILQEAM QNQVNVNPER ANPVTDPVSM
       190        200        210        220        230        240
AAPFIFTSGE VVNLASLISS TNTKTTSGDP HASTVQFSNS TTSVLATLAA LAEASVPLSN
       250        260        270        280        290        300
SHRATANTEE IIEGNSVDSS IQQVMGSGGQ RVITIVTDGV PLGNIQTSIP TGGIGQPFIV
       310        320        330        340        350        360
TVQDGQQVLT VPAGKVAEET VIKEEEEEKL PLTKKPRIGE KTNSVEESKE GNERELLQQQ
       370        380        390        400        410        420
LQEANRRAQE YRHQLLKKEQ EAEQYRLKLE AIARQQPNGV DFTMVEEVAE VDAVVVTEGE
       430        440
LEERETKVTG SAGTTEPHTR VSMATVSS

Isoforms

Sequence View

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Protease Assignment Confidence:

Evidence Names:

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Protein Neighborhood

Domains & Features

5 N-termini - 3 C-termini - 2 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q8TAK5-1-unknown	MSLVDL...	1		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q8TAK5-2-acetylation	SLVDLG...	2	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345
Q8TAK5-2-acetylation	SLVDLG...	2	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345
Q8TAK5-256-unknown	SVDSSI...	256		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC12920
Q8TAK5-259-unknown	SSIQQV...	259		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC12921
Q8TAK5-305-	GQQVLT...	305			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...IIEGNS	255	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC12920
...GNSVDS	258	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC12921
...ATVSS	448	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
GRAB_HUMAN	255	EGNS.\|.SVDS	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:Analysis of protein processing ... (S01.010)	18836177,
GRAB_HUMAN	258	SVDS.\|.SSIQ	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:Analysis of protein processing ... (S01.010)	18836177,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)