Q7Z4S6: Kinesin-like protein KIF21A

General Information

Protein names	- Kinesin-like protein KIF21A - Kinesin-like protein KIF2 - Renal carcinoma antigen NY-REN-62
Gene names	KIF21A
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q7Z4S6

6 N-termini

4 C-termini

4 Cleavages

0 Substrates

Sequence

Isoforms

- Isoform 2 of Kinesin-like protein KIF21A - Isoform 3 of Kinesin-like protein KIF21A - Isoform 4 of Kinesin-like protein KIF21A - Isoform 5 of Kinesin-like protein KIF21A - Isoform 6 of Kinesin-like protein KIF21A

Sequence View

        10         20         30         40         50         60
MLGAPDESSV RVAVRIRPQL AKEKIEGCHI CTSVTPGEPQ VFLGKDKAFT FDYVFDIDSQ
        70         80         90        100        110        120
QEQIYIQCIE KLIEGCFEGY NATVFAYGQT GAGKTYTMGT GFDVNIVEEE LGIISRAVKH
       130        140        150        160        170        180
LFKSIEEKKH IAIKNGLPAP DFKVNAQFLE LYNEEVLDLF DTTRDIDAKS KKSNIRIHED
       190        200        210        220        230        240
STGGIYTVGV TTRTVNTESE MMQCLKLGAL SRTTASTQMN VQSSRSHAIF TIHVCQTRVC
       250        260        270        280        290        300
PQIDADNATD NKIISESAQM NEFETLTAKF HFVDLAGSER LKRTGATGER AKEGISINCG
       310        320        330        340        350        360
LLALGNVISA LGDKSKRATH VPYRDSKLTR LLQDSLGGNS QTIMIACVSP SDRDFMETLN
       370        380        390        400        410        420
TLKYANRARN IKNKVMVNQD RASQQINALR SEITRLQMEL MEYKTGKRII DEEGVESIND
       430        440        450        460        470        480
MFHENAMLQT ENNNLRVRIK AMQETVDALR SRITQLVSDQ ANHVLARAGE GNEEISNMIH
       490        500        510        520        530        540
SYIKEIEDLR AKLLESEAVN ENLRKNLTRA TARAPYFSGS STFSPTILSS DKETIEIIDL
       550        560        570        580        590        600
AKKDLEKLKR KEKRKKKRLQ KLEESNREER SVAGKEDNTD TDQEKKEEKG VSERENNELE
       610        620        630        640        650        660
VEESQEVSDH EDEEEEEEEE EDDIDGGESS DESDSESDEK ANYQADLANI TCEIAIKQKL
       670        680        690        700        710        720
IDELENSQKR LQTLKKQYEE KLMMLQHKIR DTQLERDQVL QNLGSVESYS EEKAKKVRSE
       730        740        750        760        770        780
YEKKLQAMNK ELQRLQAAQK EHARLLKNQS QYEKQLKKLQ QDVMEMKKTK VRLMKQMKEE
       790        800        810        820        830        840
QEKARLTESR RNREIAQLKK DQRKRDHQLR LLEAQKRNQE VVLRRKTEEV TALRRQVRPM
       850        860        870        880        890        900
SDKVAGKVTR KLSSSDAPAQ DTGSSAAAVE TDASRTGAQQ KMRIPVARVQ ALPTPATNGN
       910        920        930        940        950        960
RKKYQRKGLT GRVFISKTAR MKWQLLERRV TDIIMQKMTI SNMEADMNRL LKQREELTKR
       970        980        990       1000       1010       1020
REKLSKRREK IVKENGEGDK NVANINEEME SLTANIDYIN DSISDCQANI MQMEEAKEEG
      1030       1040       1050       1060       1070       1080
ETLDVTAVIN ACTLTEARYL LDHFLSMGIN KGLQAAQKEA QIKVLEGRLK QTEITSATQN
      1090       1100       1110       1120       1130       1140
QLLFHMLKEK AELNPELDAL LGHALQDLDS VPLENVEDST DEDAPLNSPG SEGSTLSSDL
      1150       1160       1170       1180       1190       1200
MKLCGEVKPK NKARRRTTTQ MELLYADSSE LASDTSTGDA SLPGPLTPVA EGQEIGMNTE
      1210       1220       1230       1240       1250       1260
TSGTSAREKE LSPPPGLPSK IGSISRQSSL SEKKIPEPSP VTRRKAYEKA EKSKAKEQKH
      1270       1280       1290       1300       1310       1320
SDSGTSEASL SPPSSPPSRP RNELNVFNRL TVSQGNTSVQ QDKSDESDSS LSEVHRSSRR
      1330       1340       1350       1360       1370       1380
GIINPFPASK GIRAFPLQCI HIAEGHTKAV LCVDSTDDLL FTGSKDRTCK VWNLVTGQEI
      1390       1400       1410       1420       1430       1440
MSLGGHPNNV VSVKYCNYTS LVFTVSTSYI KVWDIRDSAK CIRTLTSSGQ VTLGDACSAS
      1450       1460       1470       1480       1490       1500
TSRTVAIPSG ENQINQIALN PTGTFLYAAS GNAVRMWDLK RFQSTGKLTG HLGPVMCLTV
      1510       1520       1530       1540       1550       1560
DQISSGQDLI ITGSKDHYIK MFDVTEGALG TVSPTHNFEP PHYDGIEALT IQGDNLFSGS
      1570       1580       1590       1600       1610       1620
RDNGIKKWDL TQKDLLQQVP NAHKDWVCAL GVVPDHPVLL SGCRGGILKV WNMDTFMPVG
      1630       1640       1650       1660       1670
EMKGHDSPIN AICVNSTHIF TAADDRTVRI WKARNLQDGQ ISDTGDLGED IASN         10         20         30         40         50         60
MLGAPDESSV RVAVRIRPQL AKEKIEGCHI CTSVTPGEPQ VFLGKDKAFT FDYVFDIDSQ
        70         80         90        100        110        120
QEQIYIQCIE KLIEGCFEGY NATVFAYGQT GAGKTYTMGT GFDVNIVEEE LGIISRAVKH
       130        140        150        160        170        180
LFKSIEEKKH IAIKNGLPAP DFKVNAQFLE LYNEEVLDLF DTTRDIDAKS KKSNIRIHED
       190        200        210        220        230        240
STGGIYTVGV TTRTVNTESE MMQCLKLGAL SRTTASTQMN VQSSRSHAIF TIHVCQTRVC
       250        260        270        280        290        300
PQIDADNATD NKIISESAQM NEFETLTAKF HFVDLAGSER LKRTGATGER AKEGISINCG
       310        320        330        340        350        360
LLALGNVISA LGDKSKRATH VPYRDSKLTR LLQDSLGGNS QTIMIACVSP SDRDFMETLN
       370        380        390        400        410        420
TLKYANRARN IKNKVMVNQD RASQQINALR SEITRLQMEL MEYKTGKRII DEEGVESIND
       430        440        450        460        470        480
MFHENAMLQT ENNNLRVRIK AMQETVDALR SRITQLVSDQ ANHVLARAGE GNEEISNMIH
       490        500        510        520        530        540
SYIKEIEDLR AKLLESEAVN ENLRKNLTRA TARAPYFSGS STFSPTILSS DKETIEIIDL
       550        560        570        580        590        600
AKKDLEKLKR KEKRKKKRLQ KLEESNREER SVAGKEDNTD TDQEKKEEKG VSERENNELE
       610        620        630        640        650        660
VEESQEVSDH EDEEEEEEEE EDDIDGGESS DESDSESDEK ANYQADLANI TCEIAIKQKL
       670        680        690        700        710        720
IDELENSQKR LQTLKKQYEE KLMMLQHKIR DTQLERDQVL QNLGSVESYS EEKAKKVRSE
       730        740        750        760        770        780
YEKKLQAMNK ELQRLQAAQK EHARLLKNQS QYEKQLKKLQ QDVMEMKKTK VRLMKQMKEE
       790        800        810        820        830        840
QEKARLTESR RNREIAQLKK DQRKRDHQLR LLEAQKRNQE VVLRRKTEEV TALRRQVRPM
       850        860        870        880        890        900
SDKVAGKVTR KLSSSDAPAQ DTGSSAAAVE TDASRTGAQQ KMRIPVARVQ ALPTPATNGN
       910        920        930        940        950        960
RKKYQRKGLT GRVFISKTAR MKWQLLERRV TDIIMQKMTI SNMEADMNRL LKQREELTKR
       970        980        990       1000       1010       1020
REKLSKRREK IVKENGEGDK NVANINEEME SLTANIDYIN DSISDCQANI MQMEEAKEEG
      1030       1040       1050       1060       1070       1080
ETLDVTAVIN ACTLTEARYL LDHFLSMGIN KGLQAAQKEA QIKVLEGRLK QTEITSATQN
      1090       1100       1110       1120       1130       1140
QLLFHMLKEK AELNPELDAL LGHALQDLDS VPLENVEDST DEDAPLNSPG SEGSTLSSDL
      1150       1160       1170       1180       1190       1200
MKLCGEVKPK NKARRRTTTQ MELLYADSSE LASDTSTGDA SLPGPLTPVA EGQEIGMNTE
      1210       1220       1230       1240       1250       1260
TSGTSAREKE LSPPPGLPSK IGSISRQSSL SEKKIPEPSP VTRRKAYEKA EKSKAKEQKH
      1270       1280       1290       1300       1310       1320
SDSGTSEASL SPPSSPPSRP RNELNVFNRL TVSQGNTSVQ QDKSDESDSS LSEVHRSSRR
      1330       1340       1350       1360       1370       1380
GIINPFPASK GIRAFPLQCI HIAEGHTKAV LCVDSTDDLL FTGSKDRTCK VWNLVTGQEI
      1390       1400       1410       1420       1430       1440
MSLGGHPNNV VSVKYCNYTS LVFTVSTSYI KVWDIRDSAK CIRTLTSSGQ VTLGDACSAS
      1450       1460       1470       1480       1490       1500
TSRTVAIPSG ENQINQIALN PTGTFLYAAS GNAVRMWDLK RFQSTGKLTG HLGPVMCLTV
      1510       1520       1530       1540       1550       1560
DQISSGQDLI ITGSKDHYIK MFDVTEGALG TVSPTHNFEP PHYDGIEALT IQGDNLFSGS
      1570       1580       1590       1600       1610       1620
RDNGIKKWDL TQKDLLQQVP NAHKDWVCAL GVVPDHPVLL SGCRGGILKV WNMDTFMPVG
      1630       1640       1650       1660       1670
EMKGHDSPIN AICVNSTHIF TAADDRTVRI WKARNLQDGQ ISDTGDLGED IASN         10         20         30         40         50         60
MLGAPDESSV RVAVRIRPQL AKEKIEGCHI CTSVTPGEPQ VFLGKDKAFT FDYVFDIDSQ
        70         80         90        100        110        120
QEQIYIQCIE KLIEGCFEGY NATVFAYGQT GAGKTYTMGT GFDVNIVEEE LGIISRAVKH
       130        140        150        160        170        180
LFKSIEEKKH IAIKNGLPAP DFKVNAQFLE LYNEEVLDLF DTTRDIDAKS KKSNIRIHED
       190        200        210        220        230        240
STGGIYTVGV TTRTVNTESE MMQCLKLGAL SRTTASTQMN VQSSRSHAIF TIHVCQTRVC
       250        260        270        280        290        300
PQIDADNATD NKIISESAQM NEFETLTAKF HFVDLAGSER LKRTGATGER AKEGISINCG
       310        320        330        340        350        360
LLALGNVISA LGDKSKRATH VPYRDSKLTR LLQDSLGGNS QTIMIACVSP SDRDFMETLN
       370        380        390        400        410        420
TLKYANRARN IKNKVMVNQD RASQQINALR SEITRLQMEL MEYKTGKRII DEEGVESIND
       430        440        450        460        470        480
MFHENAMLQT ENNNLRVRIK AMQETVDALR SRITQLVSDQ ANHVLARAGE GNEEISNMIH
       490        500        510        520        530        540
SYIKEIEDLR AKLLESEAVN ENLRKNLTRA TARAPYFSGS STFSPTILSS DKETIEIIDL
       550        560        570        580        590        600
AKKDLEKLKR KEKRKKKRLQ KLEESNREER SVAGKEDNTD TDQEKKEEKG VSERENNELE
       610        620        630        640        650        660
VEESQEVSDH EDEEEEEEEE EDDIDGGESS DESDSESDEK ANYQADLANI TCEIAIKQKL
       670        680        690        700        710        720
IDELENSQKR LQTLKKQYEE KLMMLQHKIR DTQLERDQVL QNLGSVESYS EEKAKKVRSE
       730        740        750        760        770        780
YEKKLQAMNK ELQRLQAAQK EHARLLKNQS QYEKQLKKLQ QDVMEMKKTK VRLMKQMKEE
       790        800        810        820        830        840
QEKARLTESR RNREIAQLKK DQRKRDHQLR LLEAQKRNQE VVLRRKTEEV TALRRQVRPM
       850        860        870        880        890        900
SDKVAGKVTR KLSSSDAPAQ DTGSSAAAVE TDASRTGAQQ KMRIPVARVQ ALPTPATNGN
       910        920        930        940        950        960
RKKYQRKGLT GRVFISKTAR MKWQLLERRV TDIIMQKMTI SNMEADMNRL LKQREELTKR
       970        980        990       1000       1010       1020
REKLSKRREK IVKENGEGDK NVANINEEME SLTANIDYIN DSISDCQANI MQMEEAKEEG
      1030       1040       1050       1060       1070       1080
ETLDVTAVIN ACTLTEARYL LDHFLSMGIN KGLQAAQKEA QIKVLEGRLK QTEITSATQN
      1090       1100       1110       1120       1130       1140
QLLFHMLKEK AELNPELDAL LGHALQDLDS VPLENVEDST DEDAPLNSPG SEGSTLSSDL
      1150       1160       1170       1180       1190       1200
MKLCGEVKPK NKARRRTTTQ MELLYADSSE LASDTSTGDA SLPGPLTPVA EGQEIGMNTE
      1210       1220       1230       1240       1250       1260
TSGTSAREKE LSPPPGLPSK IGSISRQSSL SEKKIPEPSP VTRRKAYEKA EKSKAKEQKH
      1270       1280       1290       1300       1310       1320
SDSGTSEASL SPPSSPPSRP RNELNVFNRL TVSQGNTSVQ QDKSDESDSS LSEVHRSSRR
      1330       1340       1350       1360       1370       1380
GIINPFPASK GIRAFPLQCI HIAEGHTKAV LCVDSTDDLL FTGSKDRTCK VWNLVTGQEI
      1390       1400       1410       1420       1430       1440
MSLGGHPNNV VSVKYCNYTS LVFTVSTSYI KVWDIRDSAK CIRTLTSSGQ VTLGDACSAS
      1450       1460       1470       1480       1490       1500
TSRTVAIPSG ENQINQIALN PTGTFLYAAS GNAVRMWDLK RFQSTGKLTG HLGPVMCLTV
      1510       1520       1530       1540       1550       1560
DQISSGQDLI ITGSKDHYIK MFDVTEGALG TVSPTHNFEP PHYDGIEALT IQGDNLFSGS
      1570       1580       1590       1600       1610       1620
RDNGIKKWDL TQKDLLQQVP NAHKDWVCAL GVVPDHPVLL SGCRGGILKV WNMDTFMPVG
      1630       1640       1650       1660       1670
EMKGHDSPIN AICVNSTHIF TAADDRTVRI WKARNLQDGQ ISDTGDLGED IASN         10         20         30         40         50         60
MLGAPDESSV RVAVRIRPQL AKEKIEGCHI CTSVTPGEPQ VFLGKDKAFT FDYVFDIDSQ
        70         80         90        100        110        120
QEQIYIQCIE KLIEGCFEGY NATVFAYGQT GAGKTYTMGT GFDVNIVEEE LGIISRAVKH
       130        140        150        160        170        180
LFKSIEEKKH IAIKNGLPAP DFKVNAQFLE LYNEEVLDLF DTTRDIDAKS KKSNIRIHED
       190        200        210        220        230        240
STGGIYTVGV TTRTVNTESE MMQCLKLGAL SRTTASTQMN VQSSRSHAIF TIHVCQTRVC
       250        260        270        280        290        300
PQIDADNATD NKIISESAQM NEFETLTAKF HFVDLAGSER LKRTGATGER AKEGISINCG
       310        320        330        340        350        360
LLALGNVISA LGDKSKRATH VPYRDSKLTR LLQDSLGGNS QTIMIACVSP SDRDFMETLN
       370        380        390        400        410        420
TLKYANRARN IKNKVMVNQD RASQQINALR SEITRLQMEL MEYKTGKRII DEEGVESIND
       430        440        450        460        470        480
MFHENAMLQT ENNNLRVRIK AMQETVDALR SRITQLVSDQ ANHVLARAGE GNEEISNMIH
       490        500        510        520        530        540
SYIKEIEDLR AKLLESEAVN ENLRKNLTRA TARAPYFSGS STFSPTILSS DKETIEIIDL
       550        560        570        580        590        600
AKKDLEKLKR KEKRKKKRLQ KLEESNREER SVAGKEDNTD TDQEKKEEKG VSERENNELE
       610        620        630        640        650        660
VEESQEVSDH EDEEEEEEEE EDDIDGGESS DESDSESDEK ANYQADLANI TCEIAIKQKL
       670        680        690        700        710        720
IDELENSQKR LQTLKKQYEE KLMMLQHKIR DTQLERDQVL QNLGSVESYS EEKAKKVRSE
       730        740        750        760        770        780
YEKKLQAMNK ELQRLQAAQK EHARLLKNQS QYEKQLKKLQ QDVMEMKKTK VRLMKQMKEE
       790        800        810        820        830        840
QEKARLTESR RNREIAQLKK DQRKRDHQLR LLEAQKRNQE VVLRRKTEEV TALRRQVRPM
       850        860        870        880        890        900
SDKVAGKVTR KLSSSDAPAQ DTGSSAAAVE TDASRTGAQQ KMRIPVARVQ ALPTPATNGN
       910        920        930        940        950        960
RKKYQRKGLT GRVFISKTAR MKWQLLERRV TDIIMQKMTI SNMEADMNRL LKQREELTKR
       970        980        990       1000       1010       1020
REKLSKRREK IVKENGEGDK NVANINEEME SLTANIDYIN DSISDCQANI MQMEEAKEEG
      1030       1040       1050       1060       1070       1080
ETLDVTAVIN ACTLTEARYL LDHFLSMGIN KGLQAAQKEA QIKVLEGRLK QTEITSATQN
      1090       1100       1110       1120       1130       1140
QLLFHMLKEK AELNPELDAL LGHALQDLDS VPLENVEDST DEDAPLNSPG SEGSTLSSDL
      1150       1160       1170       1180       1190       1200
MKLCGEVKPK NKARRRTTTQ MELLYADSSE LASDTSTGDA SLPGPLTPVA EGQEIGMNTE
      1210       1220       1230       1240       1250       1260
TSGTSAREKE LSPPPGLPSK IGSISRQSSL SEKKIPEPSP VTRRKAYEKA EKSKAKEQKH
      1270       1280       1290       1300       1310       1320
SDSGTSEASL SPPSSPPSRP RNELNVFNRL TVSQGNTSVQ QDKSDESDSS LSEVHRSSRR
      1330       1340       1350       1360       1370       1380
GIINPFPASK GIRAFPLQCI HIAEGHTKAV LCVDSTDDLL FTGSKDRTCK VWNLVTGQEI
      1390       1400       1410       1420       1430       1440
MSLGGHPNNV VSVKYCNYTS LVFTVSTSYI KVWDIRDSAK CIRTLTSSGQ VTLGDACSAS
      1450       1460       1470       1480       1490       1500
TSRTVAIPSG ENQINQIALN PTGTFLYAAS GNAVRMWDLK RFQSTGKLTG HLGPVMCLTV
      1510       1520       1530       1540       1550       1560
DQISSGQDLI ITGSKDHYIK MFDVTEGALG TVSPTHNFEP PHYDGIEALT IQGDNLFSGS
      1570       1580       1590       1600       1610       1620
RDNGIKKWDL TQKDLLQQVP NAHKDWVCAL GVVPDHPVLL SGCRGGILKV WNMDTFMPVG
      1630       1640       1650       1660       1670
EMKGHDSPIN AICVNSTHIF TAADDRTVRI WKARNLQDGQ ISDTGDLGED IASN         10         20         30         40         50         60
MLGAPDESSV RVAVRIRPQL AKEKIEGCHI CTSVTPGEPQ VFLGKDKAFT FDYVFDIDSQ
        70         80         90        100        110        120
QEQIYIQCIE KLIEGCFEGY NATVFAYGQT GAGKTYTMGT GFDVNIVEEE LGIISRAVKH
       130        140        150        160        170        180
LFKSIEEKKH IAIKNGLPAP DFKVNAQFLE LYNEEVLDLF DTTRDIDAKS KKSNIRIHED
       190        200        210        220        230        240
STGGIYTVGV TTRTVNTESE MMQCLKLGAL SRTTASTQMN VQSSRSHAIF TIHVCQTRVC
       250        260        270        280        290        300
PQIDADNATD NKIISESAQM NEFETLTAKF HFVDLAGSER LKRTGATGER AKEGISINCG
       310        320        330        340        350        360
LLALGNVISA LGDKSKRATH VPYRDSKLTR LLQDSLGGNS QTIMIACVSP SDRDFMETLN
       370        380        390        400        410        420
TLKYANRARN IKNKVMVNQD RASQQINALR SEITRLQMEL MEYKTGKRII DEEGVESIND
       430        440        450        460        470        480
MFHENAMLQT ENNNLRVRIK AMQETVDALR SRITQLVSDQ ANHVLARAGE GNEEISNMIH
       490        500        510        520        530        540
SYIKEIEDLR AKLLESEAVN ENLRKNLTRA TARAPYFSGS STFSPTILSS DKETIEIIDL
       550        560        570        580        590        600
AKKDLEKLKR KEKRKKKRLQ KLEESNREER SVAGKEDNTD TDQEKKEEKG VSERENNELE
       610        620        630        640        650        660
VEESQEVSDH EDEEEEEEEE EDDIDGGESS DESDSESDEK ANYQADLANI TCEIAIKQKL
       670        680        690        700        710        720
IDELENSQKR LQTLKKQYEE KLMMLQHKIR DTQLERDQVL QNLGSVESYS EEKAKKVRSE
       730        740        750        760        770        780
YEKKLQAMNK ELQRLQAAQK EHARLLKNQS QYEKQLKKLQ QDVMEMKKTK VRLMKQMKEE
       790        800        810        820        830        840
QEKARLTESR RNREIAQLKK DQRKRDHQLR LLEAQKRNQE VVLRRKTEEV TALRRQVRPM
       850        860        870        880        890        900
SDKVAGKVTR KLSSSDAPAQ DTGSSAAAVE TDASRTGAQQ KMRIPVARVQ ALPTPATNGN
       910        920        930        940        950        960
RKKYQRKGLT GRVFISKTAR MKWQLLERRV TDIIMQKMTI SNMEADMNRL LKQREELTKR
       970        980        990       1000       1010       1020
REKLSKRREK IVKENGEGDK NVANINEEME SLTANIDYIN DSISDCQANI MQMEEAKEEG
      1030       1040       1050       1060       1070       1080
ETLDVTAVIN ACTLTEARYL LDHFLSMGIN KGLQAAQKEA QIKVLEGRLK QTEITSATQN
      1090       1100       1110       1120       1130       1140
QLLFHMLKEK AELNPELDAL LGHALQDLDS VPLENVEDST DEDAPLNSPG SEGSTLSSDL
      1150       1160       1170       1180       1190       1200
MKLCGEVKPK NKARRRTTTQ MELLYADSSE LASDTSTGDA SLPGPLTPVA EGQEIGMNTE
      1210       1220       1230       1240       1250       1260
TSGTSAREKE LSPPPGLPSK IGSISRQSSL SEKKIPEPSP VTRRKAYEKA EKSKAKEQKH
      1270       1280       1290       1300       1310       1320
SDSGTSEASL SPPSSPPSRP RNELNVFNRL TVSQGNTSVQ QDKSDESDSS LSEVHRSSRR
      1330       1340       1350       1360       1370       1380
GIINPFPASK GIRAFPLQCI HIAEGHTKAV LCVDSTDDLL FTGSKDRTCK VWNLVTGQEI
      1390       1400       1410       1420       1430       1440
MSLGGHPNNV VSVKYCNYTS LVFTVSTSYI KVWDIRDSAK CIRTLTSSGQ VTLGDACSAS
      1450       1460       1470       1480       1490       1500
TSRTVAIPSG ENQINQIALN PTGTFLYAAS GNAVRMWDLK RFQSTGKLTG HLGPVMCLTV
      1510       1520       1530       1540       1550       1560
DQISSGQDLI ITGSKDHYIK MFDVTEGALG TVSPTHNFEP PHYDGIEALT IQGDNLFSGS
      1570       1580       1590       1600       1610       1620
RDNGIKKWDL TQKDLLQQVP NAHKDWVCAL GVVPDHPVLL SGCRGGILKV WNMDTFMPVG
      1630       1640       1650       1660       1670
EMKGHDSPIN AICVNSTHIF TAADDRTVRI WKARNLQDGQ ISDTGDLGED IASN

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

6 N-termini - 4 C-termini - 4 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q7Z4S6-1-Acetylation	MLGAPD...	1	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q7Z4S6-1-Acetylation	MLGAPD...	1	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345
Q7Z4S6-1-Acetylation	MLGAPD...	1	acetylation-		other		CNRS/ISV	Large_scale_NTA_Human
Q7Z4S6-1-Acetylation	MLGAPD...	1	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345
Q7Z4S6-1-Acetylation	MLGAPD...	1	acetylation-	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt102442
Q7Z4S6-1-Acetylation	MLGAPD...	1	acetylation-	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt102443
Q7Z4S6-1-Acetylation	MLGAPD...	1	acetylation-	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt102444
Q7Z4S6-1-Acetylation	MLGAPD...	1	acetylation-	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt102445
Q7Z4S6-1-Acetylation	MLGAPD...	1	acetylation-	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt102446
Q7Z4S6-1-	MLGAPD...	1			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
Q7Z4S6-1-unknown	MLGAPD...	1		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt78934
Q7Z4S6-1-unknown	MLGAPD...	1		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt78935
Q7Z4S6-1-unknown	MLGAPD...	1		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt78936
Q7Z4S6-1-unknown	MLGAPD...	1		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt78937
Q7Z4S6-1-unknown	MLGAPD...	1		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt78938
Q7Z4S6-532-unknown	KETIEI...	532		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC12687
Q7Z4S6-532-unknown	KETIEI...	532		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt153776
Q7Z4S6-532-unknown	KETIEI...	532		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt153777
Q7Z4S6-532-unknown	KETIEI...	532		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt153778
Q7Z4S6-532-unknown	KETIEI...	532		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt153779
Q7Z4S6-532-unknown	KETIEI...	532		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt153781
Q7Z4S6-841-unknown	SDKVAG...	841		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC14675
Q7Z4S6-841-unknown	SDKVAG...	841		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC12693
Q7Z4S6-841-unknown	SDKVAG...	841		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt156506
Q7Z4S6-841-unknown	SDKVAG...	841		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt156598
Q7Z4S6-841-unknown	SDKVAG...	841		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt156599
Q7Z4S6-841-unknown	SDKVAG...	841		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt156655
Q7Z4S6-841-unknown	SDKVAG...	841		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt156656
Q7Z4S6-1303-unknown	KSDESD...	1303		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC12699
Q7Z4S6-1303-unknown	KSDESD...	1303		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt157889

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...ILSSDK	531	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC12687
...ILSSDK	531	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt137198
...ILSSDK	531	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt137199
...ILSSDK	531	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt137200
...ILSSDK	531	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt137201
...ILSSDK	531	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt137203
...QVRPMS	840	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC14675
...QVRPMS	840	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC12693
...QVRPMS	840	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt140083
...QVRPMS	840	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt140084
...QVRPMS	840	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt140140
...QVRPMS	840	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt140141
...SVQQDK	1302	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC12699
...SVQQDK	1302	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt141386
...SVQQDK	1302	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt141399
...DIASN	1674	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...DIASN	1674	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt74556
...DIASN	1674	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt74553
...DIASN	1674	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt74555
...DIASN	1674	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt74552
...DIASN	1674	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt74554

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
GRAB_HUMAN	531	SSDK.\|.KETI	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:Analysis of protein processing ... (S01.010)	18836177,
GRAM_HUMAN	840	RPMS.\|.SDKV	inferred from experiment	unknown	MEROPS	Bovenschen N	de Poot SA et al.:Human and mouse granzyme M disp... (S01.139)	21564021,
GRAB_HUMAN	840	RPMS.\|.SDKV	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:Complementary positional proteo... (M14.017)	20526345,
GRAB_HUMAN	1302	QQDK.\|.KSDE	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:Complementary positional proteo... (M14.017)	20526345,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)