O96019: Actin-like protein 6A

General Information

Protein names	- Actin-like protein 6A - 53 kDa BRG1-associated factor A - Actin-related protein Baf53a - ArpNbeta - BRG1-associated factor 53A - BAF53A - INO80 complex subunit K
Gene names	ACTL6A
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	O96019

5 N-termini

3 C-termini

2 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MSGGVYGGDE VGALVFDIGS YTVRAGYAGE DCPKVDFPTA IGMVVERDDG STLMEIDGDK
        70         80         90        100        110        120
GKQGGPTYYI DTNALRVPRE NMEAISPLKN GMVEDWDSFQ AILDHTYKMH VKSEASLHPV
       130        140        150        160        170        180
LMSEAPWNTR AKREKLTELM FEHYNIPAFF LCKTAVLTAF ANGRSTGLIL DSGATHTTAI
       190        200        210        220        230        240
PVHDGYVLQQ GIVKSPLAGD FITMQCRELF QEMNIELVPP YMIASKEAVR EGSPANWKRK
       250        260        270        280        290        300
EKLPQVTRSW HNYMCNCVIQ DFQASVLQVS DSTYDEQVAA QMPTVHYEFP NGYNCDFGAE
       310        320        330        340        350        360
RLKIPEGLFD PSNVKGLSGN TMLGVSHVVT TSVGMCDIDI RPGLYGSVIV AGGNTLIQSF
       370        380        390        400        410        420
TDRLNRELSQ KTPPSMRLKL IANNTTVERR FSSWIGGSIL ASLGTFQQMW ISKQEYEEGG

KQCVERKCP

Isoforms

- Isoform 2 of Actin-like protein 6A

Sequence View

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Protein Neighborhood

Domains & Features

5 N-termini - 3 C-termini - 2 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
O96019-2-unknown	MSGGVY...	1		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
O96019-2-Acetylation	SGGVYG...	2	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
O96019-2-Acetylation	SGGVYG...	2	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345
O96019-43-unknown	MVVERD...	43		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt66170
O96019-58-unknown	GDKGKQ...	58		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC1511
O96019-58-unknown	GDKGKQ...	58		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt136610
O96019-60-unknown	KGKQGG...	60		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC11036
O96019-60-unknown	KGKQGG...	60		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt136699

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...LMEIDG	57	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC1511
...EIDGDK	59	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC11036
...ERKCP	429	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...ERKCP	429	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt61788

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
CASP3_HUMAN	57	EIDG.\|.GDKG	inferred from experiment	unknown	MEROPS		Merops CASP3_HUMAN -> ACL6A_HUMAN @57
GRAB_HUMAN	59	DGDK.\|.KGKQ	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:Analysis of protein processing ... (S01.010)	18836177,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)