P51532: Transcription activator BRG1
Protein names | - Transcription activator BRG1 - 3.6.4.- - ATP-dependent helicase SMARCA4 - BRG1-associated factor 190A - BAF190A - Mitotic growth and transcription activator - Protein BRG-1 - Protein brahma homolog 1 - SNF2-beta - SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4 |
---|---|
Gene names | SMARCA4 |
Organism | Homo sapiens |
Protease Family | |
Protease ID | |
Chromosome location | |
UniProt ID | P51532 |
15
N-termini
4
C-termini
3
Cleavages
0
Substrates
Sequence
10 20 30 40 50 60
MSTPDPPLGG TPRPGPSPGP GPSPGAMLGP SPGPSPGSAH SMMGPSPGPP SAGHPIPTQG
70 80 90 100 110 120
PGGYPQDNMH QMHKPMESMH EKGMSDDPRY NQMKGMGMRS GGHAGMGPPP SPMDQHSQGY
130 140 150 160 170 180
PSPLGGSEHA SSPVPASGPS SGPQMSSGPG GAPLDGADPQ ALGQQNRGPT PFNQNQLHQL
190 200 210 220 230 240
RAQIMAYKML ARGQPLPDHL QMAVQGKRPM PGMQQQMPTL PPPSVSATGP GPGPGPGPGP
250 260 270 280 290 300
GPGPAPPNYS RPHGMGGPNM PPPGPSGVPP GMPGQPPGGP PKPWPEGPMA NAAAPTSTPQ
310 320 330 340 350 360
KLIPPQPTGR PSPAPPAVPP AASPVMPPQT QSPGQPAQPA PMVPLHQKQS RITPIQKPRG
370 380 390 400 410 420
LDPVEILQER EYRLQARIAH RIQELENLPG SLAGDLRTKA TIELKALRLL NFQRQLRQEV
430 440 450 460 470 480
VVCMRRDTAL ETALNAKAYK RSKRQSLREA RITEKLEKQQ KIEQERKRRQ KHQEYLNSIL
490 500 510 520 530 540
QHAKDFKEYH RSVTGKIQKL TKAVATYHAN TEREQKKENE RIEKERMRRL MAEDEEGYRK
550 560 570 580 590 600
LIDQKKDKRL AYLLQQTDEY VANLTELVRQ HKAAQVAKEK KKKKKKKKAE NAEGQTPAIG
610 620 630 640 650 660
PDGEPLDETS QMSDLPVKVI HVESGKILTG TDAPKAGQLE AWLEMNPGYE VAPRSDSEES
670 680 690 700 710 720
GSEEEEEEEE EEQPQAAQPP TLPVEEKKKI PDPDSDDVSE VDARHIIENA KQDVDDEYGV
730 740 750 760 770 780
SQALARGLQS YYAVAHAVTE RVDKQSALMV NGVLKQYQIK GLEWLVSLYN NNLNGILADE
790 800 810 820 830 840
MGLGKTIQTI ALITYLMEHK RINGPFLIIV PLSTLSNWAY EFDKWAPSVV KVSYKGSPAA
850 860 870 880 890 900
RRAFVPQLRS GKFNVLLTTY EYIIKDKHIL AKIRWKYMIV DEGHRMKNHH CKLTQVLNTH
910 920 930 940 950 960
YVAPRRLLLT GTPLQNKLPE LWALLNFLLP TIFKSCSTFE QWFNAPFAMT GEKVDLNEEE
970 980 990 1000 1010 1020
TILIIRRLHK VLRPFLLRRL KKEVEAQLPE KVEYVIKCDM SALQRVLYRH MQAKGVLLTD
1030 1040 1050 1060 1070 1080
GSEKDKKGKG GTKTLMNTIM QLRKICNHPY MFQHIEESFS EHLGFTGGIV QGLDLYRASG
1090 1100 1110 1120 1130 1140
KFELLDRILP KLRATNHKVL LFCQMTSLMT IMEDYFAYRG FKYLRLDGTT KAEDRGMLLK
1150 1160 1170 1180 1190 1200
TFNEPGSEYF IFLLSTRAGG LGLNLQSADT VIIFDSDWNP HQDLQAQDRA HRIGQQNEVR
1210 1220 1230 1240 1250 1260
VLRLCTVNSV EEKILAAAKY KLNVDQKVIQ AGMFDQKSSS HERRAFLQAI LEHEEQDESR
1270 1280 1290 1300 1310 1320
HCSTGSGSAS FAHTAPPPAG VNPDLEEPPL KEEDEVPDDE TVNQMIARHE EEFDLFMRMD
1330 1340 1350 1360 1370 1380
LDRRREEARN PKRKPRLMEE DELPSWIIKD DAEVERLTCE EEEEKMFGRG SRHRKEVDYS
1390 1400 1410 1420 1430 1440
DSLTEKQWLK AIEEGTLEEI EEEVRQKKSS RKRKRDSDAG SSTPTTSTRS RDKDDESKKQ
1450 1460 1470 1480 1490 1500
KKRGRPPAEK LSPNPPNLTK KMKKIVDAVI KYKDSSSGRQ LSEVFIQLPS RKELPEYYEL
1510 1520 1530 1540 1550 1560
IRKPVDFKKI KERIRNHKYR SLNDLEKDVM LLCQNAQTFN LEGSLIYEDS IVLQSVFTSV
1570 1580 1590 1600 1610 1620
RQKIEKEDDS EGEESEEEEE GEEEGSESES RSVKVKIKLG RKEKAQDRLK GGRRRPSRGS
1630 1640
RAKPVVSDDD SEEEQEEDRS GSGSEED
Isoforms
- Isoform 2 of Transcription activator BRG1 - Isoform 3 of Transcription activator BRG1 - Isoform 4 of Transcription activator BRG1 - Isoform 5 of Transcription activator BRG1Sequence View
10 20 30 40 50 60
MSTPDPPLGG TPRPGPSPGP GPSPGAMLGP SPGPSPGSAH SMMGPSPGPP SAGHPIPTQG
70 80 90 100 110 120
PGGYPQDNMH QMHKPMESMH EKGMSDDPRY NQMKGMGMRS GGHAGMGPPP SPMDQHSQGY
130 140 150 160 170 180
PSPLGGSEHA SSPVPASGPS SGPQMSSGPG GAPLDGADPQ ALGQQNRGPT PFNQNQLHQL
190 200 210 220 230 240
RAQIMAYKML ARGQPLPDHL QMAVQGKRPM PGMQQQMPTL PPPSVSATGP GPGPGPGPGP
250 260 270 280 290 300
GPGPAPPNYS RPHGMGGPNM PPPGPSGVPP GMPGQPPGGP PKPWPEGPMA NAAAPTSTPQ
310 320 330 340 350 360
KLIPPQPTGR PSPAPPAVPP AASPVMPPQT QSPGQPAQPA PMVPLHQKQS RITPIQKPRG
370 380 390 400 410 420
LDPVEILQER EYRLQARIAH RIQELENLPG SLAGDLRTKA TIELKALRLL NFQRQLRQEV
430 440 450 460 470 480
VVCMRRDTAL ETALNAKAYK RSKRQSLREA RITEKLEKQQ KIEQERKRRQ KHQEYLNSIL
490 500 510 520 530 540
QHAKDFKEYH RSVTGKIQKL TKAVATYHAN TEREQKKENE RIEKERMRRL MAEDEEGYRK
550 560 570 580 590 600
LIDQKKDKRL AYLLQQTDEY VANLTELVRQ HKAAQVAKEK KKKKKKKKAE NAEGQTPAIG
610 620 630 640 650 660
PDGEPLDETS QMSDLPVKVI HVESGKILTG TDAPKAGQLE AWLEMNPGYE VAPRSDSEES
670 680 690 700 710 720
GSEEEEEEEE EEQPQAAQPP TLPVEEKKKI PDPDSDDVSE VDARHIIENA KQDVDDEYGV
730 740 750 760 770 780
SQALARGLQS YYAVAHAVTE RVDKQSALMV NGVLKQYQIK GLEWLVSLYN NNLNGILADE
790 800 810 820 830 840
MGLGKTIQTI ALITYLMEHK RINGPFLIIV PLSTLSNWAY EFDKWAPSVV KVSYKGSPAA
850 860 870 880 890 900
RRAFVPQLRS GKFNVLLTTY EYIIKDKHIL AKIRWKYMIV DEGHRMKNHH CKLTQVLNTH
910 920 930 940 950 960
YVAPRRLLLT GTPLQNKLPE LWALLNFLLP TIFKSCSTFE QWFNAPFAMT GEKVDLNEEE
970 980 990 1000 1010 1020
TILIIRRLHK VLRPFLLRRL KKEVEAQLPE KVEYVIKCDM SALQRVLYRH MQAKGVLLTD
1030 1040 1050 1060 1070 1080
GSEKDKKGKG GTKTLMNTIM QLRKICNHPY MFQHIEESFS EHLGFTGGIV QGLDLYRASG
1090 1100 1110 1120 1130 1140
KFELLDRILP KLRATNHKVL LFCQMTSLMT IMEDYFAYRG FKYLRLDGTT KAEDRGMLLK
1150 1160 1170 1180 1190 1200
TFNEPGSEYF IFLLSTRAGG LGLNLQSADT VIIFDSDWNP HQDLQAQDRA HRIGQQNEVR
1210 1220 1230 1240 1250 1260
VLRLCTVNSV EEKILAAAKY KLNVDQKVIQ AGMFDQKSSS HERRAFLQAI LEHEEQDESR
1270 1280 1290 1300 1310 1320
HCSTGSGSAS FAHTAPPPAG VNPDLEEPPL KEEDEVPDDE TVNQMIARHE EEFDLFMRMD
1330 1340 1350 1360 1370 1380
LDRRREEARN PKRKPRLMEE DELPSWIIKD DAEVERLTCE EEEEKMFGRG SRHRKEVDYS
1390 1400 1410 1420 1430 1440
DSLTEKQWLK AIEEGTLEEI EEEVRQKKSS RKRKRDSDAG SSTPTTSTRS RDKDDESKKQ
1450 1460 1470 1480 1490 1500
KKRGRPPAEK LSPNPPNLTK KMKKIVDAVI KYKDSSSGRQ LSEVFIQLPS RKELPEYYEL
1510 1520 1530 1540 1550 1560
IRKPVDFKKI KERIRNHKYR SLNDLEKDVM LLCQNAQTFN LEGSLIYEDS IVLQSVFTSV
1570 1580 1590 1600 1610 1620
RQKIEKEDDS EGEESEEEEE GEEEGSESES RSVKVKIKLG RKEKAQDRLK GGRRRPSRGS
1630 1640
RAKPVVSDDD SEEEQEEDRS GSGSEED
10 20 30 40 50 60
MSTPDPPLGG TPRPGPSPGP GPSPGAMLGP SPGPSPGSAH SMMGPSPGPP SAGHPIPTQG
70 80 90 100 110 120
PGGYPQDNMH QMHKPMESMH EKGMSDDPRY NQMKGMGMRS GGHAGMGPPP SPMDQHSQGY
130 140 150 160 170 180
PSPLGGSEHA SSPVPASGPS SGPQMSSGPG GAPLDGADPQ ALGQQNRGPT PFNQNQLHQL
190 200 210 220 230 240
RAQIMAYKML ARGQPLPDHL QMAVQGKRPM PGMQQQMPTL PPPSVSATGP GPGPGPGPGP
250 260 270 280 290 300
GPGPAPPNYS RPHGMGGPNM PPPGPSGVPP GMPGQPPGGP PKPWPEGPMA NAAAPTSTPQ
310 320 330 340 350 360
KLIPPQPTGR PSPAPPAVPP AASPVMPPQT QSPGQPAQPA PMVPLHQKQS RITPIQKPRG
370 380 390 400 410 420
LDPVEILQER EYRLQARIAH RIQELENLPG SLAGDLRTKA TIELKALRLL NFQRQLRQEV
430 440 450 460 470 480
VVCMRRDTAL ETALNAKAYK RSKRQSLREA RITEKLEKQQ KIEQERKRRQ KHQEYLNSIL
490 500 510 520 530 540
QHAKDFKEYH RSVTGKIQKL TKAVATYHAN TEREQKKENE RIEKERMRRL MAEDEEGYRK
550 560 570 580 590 600
LIDQKKDKRL AYLLQQTDEY VANLTELVRQ HKAAQVAKEK KKKKKKKKAE NAEGQTPAIG
610 620 630 640 650 660
PDGEPLDETS QMSDLPVKVI HVESGKILTG TDAPKAGQLE AWLEMNPGYE VAPRSDSEES
670 680 690 700 710 720
GSEEEEEEEE EEQPQAAQPP TLPVEEKKKI PDPDSDDVSE VDARHIIENA KQDVDDEYGV
730 740 750 760 770 780
SQALARGLQS YYAVAHAVTE RVDKQSALMV NGVLKQYQIK GLEWLVSLYN NNLNGILADE
790 800 810 820 830 840
MGLGKTIQTI ALITYLMEHK RINGPFLIIV PLSTLSNWAY EFDKWAPSVV KVSYKGSPAA
850 860 870 880 890 900
RRAFVPQLRS GKFNVLLTTY EYIIKDKHIL AKIRWKYMIV DEGHRMKNHH CKLTQVLNTH
910 920 930 940 950 960
YVAPRRLLLT GTPLQNKLPE LWALLNFLLP TIFKSCSTFE QWFNAPFAMT GEKVDLNEEE
970 980 990 1000 1010 1020
TILIIRRLHK VLRPFLLRRL KKEVEAQLPE KVEYVIKCDM SALQRVLYRH MQAKGVLLTD
1030 1040 1050 1060 1070 1080
GSEKDKKGKG GTKTLMNTIM QLRKICNHPY MFQHIEESFS EHLGFTGGIV QGLDLYRASG
1090 1100 1110 1120 1130 1140
KFELLDRILP KLRATNHKVL LFCQMTSLMT IMEDYFAYRG FKYLRLDGTT KAEDRGMLLK
1150 1160 1170 1180 1190 1200
TFNEPGSEYF IFLLSTRAGG LGLNLQSADT VIIFDSDWNP HQDLQAQDRA HRIGQQNEVR
1210 1220 1230 1240 1250 1260
VLRLCTVNSV EEKILAAAKY KLNVDQKVIQ AGMFDQKSSS HERRAFLQAI LEHEEQDESR
1270 1280 1290 1300 1310 1320
HCSTGSGSAS FAHTAPPPAG VNPDLEEPPL KEEDEVPDDE TVNQMIARHE EEFDLFMRMD
1330 1340 1350 1360 1370 1380
LDRRREEARN PKRKPRLMEE DELPSWIIKD DAEVERLTCE EEEEKMFGRG SRHRKEVDYS
1390 1400 1410 1420 1430 1440
DSLTEKQWLK AIEEGTLEEI EEEVRQKKSS RKRKRDSDAG SSTPTTSTRS RDKDDESKKQ
1450 1460 1470 1480 1490 1500
KKRGRPPAEK LSPNPPNLTK KMKKIVDAVI KYKDSSSGRQ LSEVFIQLPS RKELPEYYEL
1510 1520 1530 1540 1550 1560
IRKPVDFKKI KERIRNHKYR SLNDLEKDVM LLCQNAQTFN LEGSLIYEDS IVLQSVFTSV
1570 1580 1590 1600 1610 1620
RQKIEKEDDS EGEESEEEEE GEEEGSESES RSVKVKIKLG RKEKAQDRLK GGRRRPSRGS
1630 1640
RAKPVVSDDD SEEEQEEDRS GSGSEED
10 20 30 40 50 60
MSTPDPPLGG TPRPGPSPGP GPSPGAMLGP SPGPSPGSAH SMMGPSPGPP SAGHPIPTQG
70 80 90 100 110 120
PGGYPQDNMH QMHKPMESMH EKGMSDDPRY NQMKGMGMRS GGHAGMGPPP SPMDQHSQGY
130 140 150 160 170 180
PSPLGGSEHA SSPVPASGPS SGPQMSSGPG GAPLDGADPQ ALGQQNRGPT PFNQNQLHQL
190 200 210 220 230 240
RAQIMAYKML ARGQPLPDHL QMAVQGKRPM PGMQQQMPTL PPPSVSATGP GPGPGPGPGP
250 260 270 280 290 300
GPGPAPPNYS RPHGMGGPNM PPPGPSGVPP GMPGQPPGGP PKPWPEGPMA NAAAPTSTPQ
310 320 330 340 350 360
KLIPPQPTGR PSPAPPAVPP AASPVMPPQT QSPGQPAQPA PMVPLHQKQS RITPIQKPRG
370 380 390 400 410 420
LDPVEILQER EYRLQARIAH RIQELENLPG SLAGDLRTKA TIELKALRLL NFQRQLRQEV
430 440 450 460 470 480
VVCMRRDTAL ETALNAKAYK RSKRQSLREA RITEKLEKQQ KIEQERKRRQ KHQEYLNSIL
490 500 510 520 530 540
QHAKDFKEYH RSVTGKIQKL TKAVATYHAN TEREQKKENE RIEKERMRRL MAEDEEGYRK
550 560 570 580 590 600
LIDQKKDKRL AYLLQQTDEY VANLTELVRQ HKAAQVAKEK KKKKKKKKAE NAEGQTPAIG
610 620 630 640 650 660
PDGEPLDETS QMSDLPVKVI HVESGKILTG TDAPKAGQLE AWLEMNPGYE VAPRSDSEES
670 680 690 700 710 720
GSEEEEEEEE EEQPQAAQPP TLPVEEKKKI PDPDSDDVSE VDARHIIENA KQDVDDEYGV
730 740 750 760 770 780
SQALARGLQS YYAVAHAVTE RVDKQSALMV NGVLKQYQIK GLEWLVSLYN NNLNGILADE
790 800 810 820 830 840
MGLGKTIQTI ALITYLMEHK RINGPFLIIV PLSTLSNWAY EFDKWAPSVV KVSYKGSPAA
850 860 870 880 890 900
RRAFVPQLRS GKFNVLLTTY EYIIKDKHIL AKIRWKYMIV DEGHRMKNHH CKLTQVLNTH
910 920 930 940 950 960
YVAPRRLLLT GTPLQNKLPE LWALLNFLLP TIFKSCSTFE QWFNAPFAMT GEKVDLNEEE
970 980 990 1000 1010 1020
TILIIRRLHK VLRPFLLRRL KKEVEAQLPE KVEYVIKCDM SALQRVLYRH MQAKGVLLTD
1030 1040 1050 1060 1070 1080
GSEKDKKGKG GTKTLMNTIM QLRKICNHPY MFQHIEESFS EHLGFTGGIV QGLDLYRASG
1090 1100 1110 1120 1130 1140
KFELLDRILP KLRATNHKVL LFCQMTSLMT IMEDYFAYRG FKYLRLDGTT KAEDRGMLLK
1150 1160 1170 1180 1190 1200
TFNEPGSEYF IFLLSTRAGG LGLNLQSADT VIIFDSDWNP HQDLQAQDRA HRIGQQNEVR
1210 1220 1230 1240 1250 1260
VLRLCTVNSV EEKILAAAKY KLNVDQKVIQ AGMFDQKSSS HERRAFLQAI LEHEEQDESR
1270 1280 1290 1300 1310 1320
HCSTGSGSAS FAHTAPPPAG VNPDLEEPPL KEEDEVPDDE TVNQMIARHE EEFDLFMRMD
1330 1340 1350 1360 1370 1380
LDRRREEARN PKRKPRLMEE DELPSWIIKD DAEVERLTCE EEEEKMFGRG SRHRKEVDYS
1390 1400 1410 1420 1430 1440
DSLTEKQWLK AIEEGTLEEI EEEVRQKKSS RKRKRDSDAG SSTPTTSTRS RDKDDESKKQ
1450 1460 1470 1480 1490 1500
KKRGRPPAEK LSPNPPNLTK KMKKIVDAVI KYKDSSSGRQ LSEVFIQLPS RKELPEYYEL
1510 1520 1530 1540 1550 1560
IRKPVDFKKI KERIRNHKYR SLNDLEKDVM LLCQNAQTFN LEGSLIYEDS IVLQSVFTSV
1570 1580 1590 1600 1610 1620
RQKIEKEDDS EGEESEEEEE GEEEGSESES RSVKVKIKLG RKEKAQDRLK GGRRRPSRGS
1630 1640
RAKPVVSDDD SEEEQEEDRS GSGSEED
10 20 30 40 50 60
MSTPDPPLGG TPRPGPSPGP GPSPGAMLGP SPGPSPGSAH SMMGPSPGPP SAGHPIPTQG
70 80 90 100 110 120
PGGYPQDNMH QMHKPMESMH EKGMSDDPRY NQMKGMGMRS GGHAGMGPPP SPMDQHSQGY
130 140 150 160 170 180
PSPLGGSEHA SSPVPASGPS SGPQMSSGPG GAPLDGADPQ ALGQQNRGPT PFNQNQLHQL
190 200 210 220 230 240
RAQIMAYKML ARGQPLPDHL QMAVQGKRPM PGMQQQMPTL PPPSVSATGP GPGPGPGPGP
250 260 270 280 290 300
GPGPAPPNYS RPHGMGGPNM PPPGPSGVPP GMPGQPPGGP PKPWPEGPMA NAAAPTSTPQ
310 320 330 340 350 360
KLIPPQPTGR PSPAPPAVPP AASPVMPPQT QSPGQPAQPA PMVPLHQKQS RITPIQKPRG
370 380 390 400 410 420
LDPVEILQER EYRLQARIAH RIQELENLPG SLAGDLRTKA TIELKALRLL NFQRQLRQEV
430 440 450 460 470 480
VVCMRRDTAL ETALNAKAYK RSKRQSLREA RITEKLEKQQ KIEQERKRRQ KHQEYLNSIL
490 500 510 520 530 540
QHAKDFKEYH RSVTGKIQKL TKAVATYHAN TEREQKKENE RIEKERMRRL MAEDEEGYRK
550 560 570 580 590 600
LIDQKKDKRL AYLLQQTDEY VANLTELVRQ HKAAQVAKEK KKKKKKKKAE NAEGQTPAIG
610 620 630 640 650 660
PDGEPLDETS QMSDLPVKVI HVESGKILTG TDAPKAGQLE AWLEMNPGYE VAPRSDSEES
670 680 690 700 710 720
GSEEEEEEEE EEQPQAAQPP TLPVEEKKKI PDPDSDDVSE VDARHIIENA KQDVDDEYGV
730 740 750 760 770 780
SQALARGLQS YYAVAHAVTE RVDKQSALMV NGVLKQYQIK GLEWLVSLYN NNLNGILADE
790 800 810 820 830 840
MGLGKTIQTI ALITYLMEHK RINGPFLIIV PLSTLSNWAY EFDKWAPSVV KVSYKGSPAA
850 860 870 880 890 900
RRAFVPQLRS GKFNVLLTTY EYIIKDKHIL AKIRWKYMIV DEGHRMKNHH CKLTQVLNTH
910 920 930 940 950 960
YVAPRRLLLT GTPLQNKLPE LWALLNFLLP TIFKSCSTFE QWFNAPFAMT GEKVDLNEEE
970 980 990 1000 1010 1020
TILIIRRLHK VLRPFLLRRL KKEVEAQLPE KVEYVIKCDM SALQRVLYRH MQAKGVLLTD
1030 1040 1050 1060 1070 1080
GSEKDKKGKG GTKTLMNTIM QLRKICNHPY MFQHIEESFS EHLGFTGGIV QGLDLYRASG
1090 1100 1110 1120 1130 1140
KFELLDRILP KLRATNHKVL LFCQMTSLMT IMEDYFAYRG FKYLRLDGTT KAEDRGMLLK
1150 1160 1170 1180 1190 1200
TFNEPGSEYF IFLLSTRAGG LGLNLQSADT VIIFDSDWNP HQDLQAQDRA HRIGQQNEVR
1210 1220 1230 1240 1250 1260
VLRLCTVNSV EEKILAAAKY KLNVDQKVIQ AGMFDQKSSS HERRAFLQAI LEHEEQDESR
1270 1280 1290 1300 1310 1320
HCSTGSGSAS FAHTAPPPAG VNPDLEEPPL KEEDEVPDDE TVNQMIARHE EEFDLFMRMD
1330 1340 1350 1360 1370 1380
LDRRREEARN PKRKPRLMEE DELPSWIIKD DAEVERLTCE EEEEKMFGRG SRHRKEVDYS
1390 1400 1410 1420 1430 1440
DSLTEKQWLK AIEEGTLEEI EEEVRQKKSS RKRKRDSDAG SSTPTTSTRS RDKDDESKKQ
1450 1460 1470 1480 1490 1500
KKRGRPPAEK LSPNPPNLTK KMKKIVDAVI KYKDSSSGRQ LSEVFIQLPS RKELPEYYEL
1510 1520 1530 1540 1550 1560
IRKPVDFKKI KERIRNHKYR SLNDLEKDVM LLCQNAQTFN LEGSLIYEDS IVLQSVFTSV
1570 1580 1590 1600 1610 1620
RQKIEKEDDS EGEESEEEEE GEEEGSESES RSVKVKIKLG RKEKAQDRLK GGRRRPSRGS
1630 1640
RAKPVVSDDD SEEEQEEDRS GSGSEED
Protein Neighborhood
Domains & Features
15 N-termini - 4 C-termini - 3 Cleavages - 0 Substrates
N-termini
Name | Sequence | Position | Modification | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMID) |
---|---|---|---|---|---|---|---|---|---|
P51532-1-unknown | MSTPDP... | 1 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
P51532-1-unknown | MSTPDP... | 1 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt90012 | |||
P51532-1-unknown | MSTPDP... | 1 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt90013 | |||
P51532-1-unknown | MSTPDP... | 1 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt90014 | |||
P51532-1-unknown | MSTPDP... | 1 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt90015 | |||
P51532-2-acetylation | STPDPP... | 2 | acetylation- | COFRADIC | Gevaert K. | Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates... | 20526345 | ||
P51532-2-acetylation | STPDPP... | 2 | acetylation- | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt178948 | ||
P51532-2-acetylation | STPDPP... | 2 | acetylation- | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt178949 | ||
P51532-2-acetylation | STPDPP... | 2 | acetylation- | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt178950 | ||
P51532-2-acetylation | STPDPP... | 2 | acetylation- | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt178951 | ||
P51532-156-unknown | GADPQA... | 156 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt171617 | |||
P51532-156-unknown | GADPQA... | 156 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt171618 | |||
P51532-156-unknown | GADPQA... | 156 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt171619 | |||
P51532-156-unknown | GADPQA... | 156 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt171620 | |||
P51532-156- | GADPQA... | 156 | Subtiligase Based Positive Selection | Wells | apoptotic_Jurkat_staurotrail | 23264352 | |||
P51532-293- | AAPTST... | 293 | Subtiligase Based Positive Selection | Wells | apoptotic_Jurkat_staurotrail | 23264352 | |||
P51532-293-unknown | AAPTST... | 293 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt173629 | |||
P51532-293-unknown | AAPTST... | 293 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt173630 | |||
P51532-293-unknown | AAPTST... | 293 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt173631 | |||
P51532-293-unknown | AAPTST... | 293 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt173632 | |||
P51532-603- | GEPLDE... | 603 | Subtiligase Based Positive Selection | Wells | apoptotic_MM1s_bort | 23264352 | |||
P51532-603-unknown | GEPLDE... | 603 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt175390 | |||
P51532-603-unknown | GEPLDE... | 603 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt175391 | |||
P51532-603-unknown | GEPLDE... | 603 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt175392 | |||
P51532-603-unknown | GEPLDE... | 603 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt175393 | |||
P51532-641- | AWLEMN... | 641 | Subtiligase Based Positive Selection | Wells | apoptotic_MM1s_bort | 23264352 | |||
P51532-641- | AWLEMN... | 641 | Subtiligase Based Positive Selection | Wells | apoptotic_MM1SDBJurkat_Mix | 23264352 | |||
P51532-641-unknown | AWLEMN... | 641 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt175395 | |||
P51532-641-unknown | AWLEMN... | 641 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt175396 | |||
P51532-641-unknown | AWLEMN... | 641 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt175397 | |||
P51532-641-unknown | AWLEMN... | 641 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt175398 | |||
P51532-695-unknown | SDDVSE... | 695 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC11633 | |||
P51532-695-unknown | SDDVSE... | 695 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt155814 | |||
P51532-695-unknown | SDDVSE... | 695 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt155815 | |||
P51532-695-unknown | SDDVSE... | 695 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt155816 | |||
P51532-695-unknown | SDDVSE... | 695 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt155817 | |||
P51532-1352-unknown | AEVERL... | 1352 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC11638 | |||
P51532-1352-unknown | AEVERL... | 1352 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt157926 | |||
P51532-1352-unknown | AEVERL... | 1352 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt157927 | |||
P51532-1352-unknown | AEVERL... | 1352 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt157928 | |||
P51532-1352-unknown | AEVERL... | 1352 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt157929 | |||
P51532-1390-unknown | KAIEEG... | 1390 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC14184 | |||
P51532-1390-unknown | KAIEEG... | 1390 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt157969 | |||
P51532-1390-unknown | KAIEEG... | 1390 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt157970 | |||
P51532-1390-unknown | KAIEEG... | 1390 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt200666 | |||
P51532-1390-unknown | KAIEEG... | 1390 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt200667 | |||
P51532-1391-unknown | AIEEGT... | 1391 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt176865 | |||
P51532-1391-unknown | AIEEGT... | 1391 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt176868 | |||
P51532-1391-unknown | AIEEGT... | 1391 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt176866 | |||
P51532-1391-unknown | AIEEGT... | 1391 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt176867 | |||
P51532-1391- | AIEEGT... | 1391 | Subtiligase Based Positive Selection | Wells | apoptotic_MM1SDBJurkat_Mix | 23264352 |
C-termini
Name | Sequence | Position | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
---|---|---|---|---|---|---|---|---|
...IPDPDS | 694 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC11633 | |||
...IPDPDS | 694 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt139266 | |||
...IPDPDS | 694 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt139267 | |||
...IPDPDS | 694 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt139268 | |||
...IPDPDS | 694 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt139269 | |||
...IIKDDA | 1351 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC11638 | |||
...IIKDDA | 1351 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt141421 | |||
...IIKDDA | 1351 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt141422 | |||
...IIKDDA | 1351 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt141423 | |||
...IIKDDA | 1351 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt141424 | |||
...EKQWLK | 1389 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC14184 | |||
...EKQWLK | 1389 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt141464 | |||
...EKQWLK | 1389 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt141465 | |||
...GSEED | 1647 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
...GSEED | 1647 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt85633 | |||
...GSEED | 1647 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt85630 | |||
...GSEED | 1647 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt85631 | |||
...GSEED | 1647 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt85632 |
Cleavages
Protease | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
---|---|---|---|---|---|---|---|---|
GRAB_HUMAN | 694 | DPDS.|.SDDV | inferred from experiment | unknown | MEROPS | Gevaert K | Van Damme P et al.:Complementary positional proteo... (M14.017) | 20526345, |
GRAB_HUMAN | 1351 | KDDA.|.AEVE | inferred from experiment | unknown | MEROPS | Gevaert K | Van Damme P et al.:Analysis of protein processing ... (S01.010) | 18836177, |
GRAM_HUMAN | 1389 | QWLK.|.KAIE | inferred from experiment | unknown | MEROPS | Bovenschen N | de Poot SA et al.:Human and mouse granzyme M disp... (S01.139) | 21564021, |
Substrates
Substrate | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
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