TopFIND 4.0

Q9NRY4: Rho GTPase-activating protein 35 {ECO:0000312|HGNC:HGNC:4591}

General Information

Protein names
- Rho GTPase-activating protein 35 {ECO:0000312|HGNC:HGNC:4591}
- Glucocorticoid receptor DNA-binding factor 1
- Glucocorticoid receptor repression factor 1
- GRF-1
- Rho GAP p190A
- p190-A {ECO:0000303|PubMed:11054565}
Gene names ARHGAP35
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID Q9NRY4

2

N-termini

2

C-termini

1

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MMMARKQDVR IPTYNISVVG LSGTEKEKGQ CGIGKSCLCN RFVRPSADEF HLDHTSVLST 
        70         80         90        100        110        120 
SDFGGRVVNN DHFLYWGEVS RSLEDCVECK MHIVEQTEFI DDQTFQPHRS TALQPYIKRA 
       130        140        150        160        170        180 
AATKLASAEK LMYFCTDQLG LEQDFEQKQM PDGKLLVDGF LLGIDVSRGM NRNFDDQLKF 
       190        200        210        220        230        240 
VSNLYNQLAK TKKPIVVVLT KCDEGVERYI RDAHTFALSK KNLQVVETSA RSNVNVDLAF 
       250        260        270        280        290        300 
STLVQLIDKS RGKTKIIPYF EALKQQSQQI ATAKDKYEWL VSRIVKNHNE NWLSVSRKMQ 
       310        320        330        340        350        360 
ASPEYQDYVY LEGTQKAKKL FLQHIHRLKH EHIERRRKLY LAALPLAFEA LIPNLDEIDH 
       370        380        390        400        410        420 
LSCIKAKKLL ETKPEFLKWF VVLEETPWDA TSHIDNMENE RIPFDLMDTV PAEQLYEAHL 
       430        440        450        460        470        480 
EKLRNERKRV EMRRAFKENL ETSPFITPGK PWEEARSFIM NEDFYQWLEE SVYMDIYGKH 
       490        500        510        520        530        540 
QKQIIDKAKE EFQELLLEYS ELFYELELDA KPSKEKMGVI QDVLGEEQRF KALQKLQAER 
       550        560        570        580        590        600 
DALILKHIHF VYHPTKETCP SCPACVDAKI EHLISSRFIR PSDRNQKNSL SDPNIDRINL 
       610        620        630        640        650        660 
VILGKDGLAR ELANEIRALC TNDDKYVIDG KMYELSLRPI EGNVRLPVNS FQTPTFQPHG 
       670        680        690        700        710        720 
CLCLYNSKES LSYVVESIEK SRESTLGRRD NHLVHLPLTL ILVNKRGDTS GETLHSLIQQ 
       730        740        750        760        770        780 
GQQIASKLQC VFLDPASAGI GYGRNINEKQ ISQVLKGLLD SKRNLNLVSS TASIKDLADV 
       790        800        810        820        830        840 
DLRIVMCLMC GDPFSADDIL FPVLQSQTCK SSHCGSNNSV LLELPIGLHK KRIELSVLSY 
       850        860        870        880        890        900 
HSSFSIRKSR LVHGYIVFYS AKRKASLAML RAFLCEVQDI IPIQLVALTD GAVDVLDNDL 
       910        920        930        940        950        960 
SREQLTEGEE IAQEIDGRFT SIPCSQPQHK LEIFHPFFKD VVEKKNIIEA THMYDNAAEA 
       970        980        990       1000       1010       1020 
CSTTEEVFNS PRAGSPLCNS NLQDSEEDIE PSYSLFREDT SLPSLSKDHS KLSMELEGND 
      1030       1040       1050       1060       1070       1080 
GLSFIMSNFE SKLNNKVPPP VKPKPPVHFE ITKGDLSYLD QGHRDGQRKS VSSSPWLPQD 
      1090       1100       1110       1120       1130       1140 
GFDPSDYAEP MDAVVKPRNE EENIYSVPHD STQGKIITIR NINKAQSNGS GNGSDSEMDT 
      1150       1160       1170       1180       1190       1200 
SSLERGRKVS IVSKPVLYRT RCTRLGRFAS YRTSFSVGSD DELGPIRKKE EDQASQGYKG 
      1210       1220       1230       1240       1250       1260 
DNAVIPYETD EDPRRRNILR SLRRNTKKPK PKPRPSITKA TWESNYFGVP LTTVVTPEKP 
      1270       1280       1290       1300       1310       1320 
IPIFIERCIE YIEATGLSTE GIYRVSGNKS EMESLQRQFD QDHNLDLAEK DFTVNTVAGA 
      1330       1340       1350       1360       1370       1380 
MKSFFSELPD PLVPYNMQID LVEAHKINDR EQKLHALKEV LKKFPKENHE VFKYVISHLN 
      1390       1400       1410       1420       1430       1440 
KVSHNNKVNL MTSENLSICF WPTLMRPDFS TMDALTATRT YQTIIELFIQ QCPFFFYNRP 
      1450       1460       1470       1480       1490    
ITEPPGARPS SPSAVASTVP FLTSTPVTSQ PSPPQSPPPT PQSPMQPLLP SQLQAEHTL

Isoforms



Sequence View



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Protein Neighborhood

Domains & Features

2 N-termini - 2 C-termini - 1 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q9NRY4-1-unknown MMMARK... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    Q9NRY4-446-unknown ITPGKP... 446 inferred from cleavage unknown TopFIND Inferred from cleavage TC13400

C-termini

Cleavages

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)