O95684: FGFR1 oncogene partner

General Information

Protein names	- FGFR1 oncogene partner
Gene names	FGFR1OP
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	O95684

5 N-termini

3 C-termini

2 Cleavages

0 Substrates

Sequence

Isoforms

- Isoform 2 of FGFR1 oncogene partner - Isoform 3 of FGFR1 oncogene partner

Sequence View

        10         20         30         40         50         60
MAATAAAVVA EEDTELRDLL VQTLENSGVL NRIKAELRAA VFLALEEQEK VENKTPLVNE
        70         80         90        100        110        120
SLKKFLNTKD GRLVASLVAE FLQFFNLDFT LAVFQPETST LQGLEGRENL ARDLGIIEAE
       130        140        150        160        170        180
GTVGGPLLLE VIRRCQQKEK GPTTGEGALD LSDVHSPPKS PEGKTSAQTT PSKIPRYKGQ
       190        200        210        220        230        240
GKKKTSGQKA GDKKANDEAN QSDTSVSLSE PKSKSSLHLL SHETKIGSFL SNRTLDGKDK
       250        260        270        280        290        300
AGLCPDEDDM EGDSFFDDPI PKPEKTYGLR KEPRKQAGSL ASLSDAPPLK SGLSSLAGAP
       310        320        330        340        350        360
SLKDSESKRG NTVLKDLKLI SDKIGSLGLG TGEDDDYVDD FNSTSHRSEK SEISIGEEIE
       370        380        390
EDLSVEIDDI NTSDKLDDLT QDLTVSQLSD VADYLEDVA         10         20         30         40         50         60
MAATAAAVVA EEDTELRDLL VQTLENSGVL NRIKAELRAA VFLALEEQEK VENKTPLVNE
        70         80         90        100        110        120
SLKKFLNTKD GRLVASLVAE FLQFFNLDFT LAVFQPETST LQGLEGRENL ARDLGIIEAE
       130        140        150        160        170        180
GTVGGPLLLE VIRRCQQKEK GPTTGEGALD LSDVHSPPKS PEGKTSAQTT PSKIPRYKGQ
       190        200        210        220        230        240
GKKKTSGQKA GDKKANDEAN QSDTSVSLSE PKSKSSLHLL SHETKIGSFL SNRTLDGKDK
       250        260        270        280        290        300
AGLCPDEDDM EGDSFFDDPI PKPEKTYGLR KEPRKQAGSL ASLSDAPPLK SGLSSLAGAP
       310        320        330        340        350        360
SLKDSESKRG NTVLKDLKLI SDKIGSLGLG TGEDDDYVDD FNSTSHRSEK SEISIGEEIE
       370        380        390
EDLSVEIDDI NTSDKLDDLT QDLTVSQLSD VADYLEDVA

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

5 N-termini - 3 C-termini - 2 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
O95684-1-unknown	MAATAA...	1		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
O95684-1-unknown	MAATAA...	1		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt75440
O95684-2-acetylation	AATAAA...	2	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345
O95684-2-acetylation	AATAAA...	2	acetylation-	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt162596
O95684-250-unknown	MEGDSF...	250		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt75441
O95684-250-unknown	MEGDSF...	250		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt105766
O95684-254-unknown	SFFDDP...	254		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC11029
O95684-254-unknown	SFFDDP...	254		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt147863
O95684-254-unknown	SFFDDP...	254		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt198344
O95684-294-unknown	SSLAGA...	294		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC13878
O95684-294-unknown	SSLAGA...	294		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt138716
O95684-294-unknown	SSLAGA...	294		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt149208

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...DMEGDS	253	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC11029
...DMEGDS	253	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt131218
...LKSGLS	293	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC13878
...LKSGLS	293	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt121770
...LKSGLS	293	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt132593
...LEDVA	399	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...LEDVA	399	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt71058

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
GRAB_HUMAN	253	EGDS.\|.SFFD	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:Analysis of protein processing ... (S01.010)	18836177,
GRAM_HUMAN	293	SGLS.\|.SSLA	inferred from experiment	unknown	MEROPS	Bovenschen N	de Poot SA et al.:Human and mouse granzyme M disp... (S01.139)	21564021,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)